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Results for “PCSK9 Inhibitor”

84 trials

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Showing 20 of 84 results

Post-approval studies (Phase 4)Not Yet RecruitingNCT07036991
What this trial is testing

Clinical Trial of PCSK9 Inhibitor and Statin Treatment for Carotid Artery Stenosis

Who this might be right for
Carotid Artery Stenosis
Changhai Hospital 406
Not applicableUnknownNCT03355027
What this trial is testing

Investigating the Lowest Threshold of Vascular Benefits From LDL Cholesterol Lowering in Patients With Stable CV Disease

Who this might be right for
AtherosclerosisCardiovascular Diseases
Cambridge University Hospitals NHS Foundation Trust 60
Large-scale testing (Phase 3)Study completedNCT01763905
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2

Who this might be right for
Hyperlipidemia
Amgen 307
Early research (Phase 1)Study completedNCT04169386
What this trial is testing

PCSK9 Inhibitor AK102 in Healthy Subjects

Who this might be right for
Hypercholesterolaemia
Akeso 32
Not applicableUnknownNCT06034691
What this trial is testing

Exploratory Research of PCSK9 Inhibitor on Patency of aAVF After PTA With PCB

Who this might be right for
Hemodialysis Access Failure
RenJi Hospital 40
Early research (Phase 1)Study completedNCT05070390
What this trial is testing

Enlicitide Chloride (MK-0616 Oral PCSK9 Inhibitor) in Participants With Moderate Renal Impairment (MK-0616-007)

Who this might be right for
Moderate Renal Impairment
Merck Sharp & Dohme LLC 18
Large-scale testing (Phase 3)UnknownNCT03634293
What this trial is testing

Treatment of Severe Infection With Antihyperlipidemia Drug

Who this might be right for
SepsisSeptic Shock
Wolfson Medical Center 712
Testing effectiveness (Phase 2)Active Not RecruitingNCT05553834
What this trial is testing

PCSK9 Inhibitor and PD-1 Inhibitor in Patients With Metastatic, Refractory To Prior Anti PD-1 Non-small Cell Lung

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Duke University 60
Not applicableNot Yet RecruitingNCT06730802
What this trial is testing

Protective Effect of PCSK9 Inhibitor Against Negative Inflammatory Response and Organ Dysfunction After Coronary Artery Bypass Grafting (PANDA VIII)

Who this might be right for
Myocardial Ischaemic SyndromeCoronary Heart Disease
Nanjing Medical University 400
Post-approval studies (Phase 4)Study completedNCT06431763
What this trial is testing

Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Who this might be right for
Hypercholesterolemia
Novartis Pharmaceuticals 402
Post-approval studies (Phase 4)Not Yet RecruitingNCT06083961
What this trial is testing

The Effect of Early Administration of PCSK9 Inhibitor to Acute Ischemic Stroke Patients Associated With Atherosclerosis on the Stroke Prognosis and Lipid Profile

Who this might be right for
Stroke, Acute IschemicPCSK9 Inhibitor
Sun U. Kwon 200
Post-approval studies (Phase 4)Looking for participantsNCT06696820
What this trial is testing

Efficacy and Safety of Early Combined Therapy with PCSK9 Inhibitors and Statins in Acute Ischemic Stroke

Who this might be right for
Acute Ischemic Stroke
Xiang Luo 416
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017) CORALreef HeFH

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Large-scale testing (Phase 3)Study completedNCT02634580
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4

Who this might be right for
Hypercholesterolemia
Amgen 61
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07014215
What this trial is testing

PD-1 Combined With Bevacizumab and PCSK-9 Inhibitor in Patients With Advanced NSCLC Who Have Progressed After Anti- PD- 1/L1 Therapy

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)Resistance to Immunotherapy
Anhui Provincial Cancer Hospital 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07061535
What this trial is testing

Sintilimab Combined With Tafolecimab and Chemotherapy as First-Line Treatment for Extensive-Stage Small Cell Lung Cancer

Who this might be right for
Extensive-stage Small Cell Lung Cancer (ES-SCLC)Extensive Stage Lung Small Cell CancerExtensive-Stage Small-Cell Lung Cancer+1 more
Second Affiliated Hospital, School of Medicine, Zhejiang University 40
Not applicableUnknownNCT06134635
What this trial is testing

Short-term Effect of PCSK9 Inhibitor in Patients With Acute Ischemic Stroke

Who this might be right for
Acute Ischemic Stroke
Xuanwu Hospital, Beijing 80
Large-scale testing (Phase 3)Study completedNCT05952856
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 2,912
Post-approval studies (Phase 4)Looking for participantsNCT07295366
What this trial is testing

Early Administration of PCSK9 Inhibitors After Thrombectomy for Atherosclerotic Acute Ischemic Stroke: A Randomized Controlled Trial

Who this might be right for
Acute Stroke
The Affiliated Hospital of Xuzhou Medical University 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06933251
What this trial is testing

PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Guangdong Provincial People's Hospital 30
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