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Results for “PD-1/L1 Inhibitor”

138 trials

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Showing 20 of 138 results

Testing effectiveness (Phase 2)Looking for participantsNCT07130032
What this trial is testing

Efficacy And Safety Of Anti-PD-1/PD-L1 Antibodies In Combination With Bevacizumab And Metronomic Cyclophosphamide In Patients With Non-Small Cell Lung Cancer And Cutaneous Melanoma Previously Treated With Immune Checkpoint Blockade

Who this might be right for
Metastatic Non-small Cell Lung Cancer (NSCLC)Metastatic Cutaneous Melanoma
EuroCityClinic LLC 90
Not applicableNot Yet RecruitingNCT06708650
What this trial is testing

Combination of SFRT, PD-L1 Inhibitor, and Anti-VEGF in Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaRadiotherapyPD-1 Inhibitors
Guiping People's Hospital 50
Testing effectiveness (Phase 2)Study completedNCT04740307
What this trial is testing

Safety and Efficacy of Coformulated Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib (E7080/MK-7902) in Advanced Hepatocellular Carcinoma (MK-1308A-004)

Who this might be right for
Advanced Hepatocellular Carcinoma
Merck Sharp & Dohme LLC 116
Large-scale testing (Phase 3)Study completedNCT05809336
What this trial is testing

Gut Microbial Metabolites Inosine Combined With PD-1/PD-L1 Inhibitor for Patients With Malignant Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Beijing Friendship Hospital 172
Large-scale testing (Phase 3)Active Not RecruitingNCT05374512
What this trial is testing

Dato-DXd Versus Investigator's Choice Chemotherapy in Patients With Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer, Who Are Not Candidates for PD-1/PD-L1 Inhibitor Therapy (TROPION-Breast02)

Who this might be right for
Breast Cancer
AstraZeneca 644
Large-scale testing (Phase 3)Study completedNCT03515837
What this trial is testing

Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 492
Early research (Phase 1)Looking for participantsNCT05338658
What this trial is testing

Study of PAT in Patients With Solid Tumor Cancers

Who this might be right for
MetastasisSolid Tumor
Masonic Cancer Center, University of Minnesota 21
Testing effectiveness (Phase 2)Active Not RecruitingNCT03600701
What this trial is testing

Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaRefractory Lung Non-Small Cell Carcinoma+1 more
National Cancer Institute (NCI) 53
Testing effectiveness (Phase 2)Active Not RecruitingNCT05604560
What this trial is testing

A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer

Who this might be right for
Pancreatic Cancer
Lei Zheng 25
Testing effectiveness (Phase 2)Study completedNCT04995419
What this trial is testing

Evaluate Enfortumab Vedotin (ASG-22CE) in Chinese Participants With Locally Advanced or Metastatic Urothelial Cancer Who Previously Received Platinum-containing Chemotherapy and Programmed Cell Death Protein-1 ( PD 1) / (Programmed Death Ligand-1 (PD-L1) Inhibitor Therapy

Who this might be right for
Metastatic Urothelial Cancer
Astellas Pharma China, Inc. 40
Early research (Phase 1)Ended earlyNCT04458259
What this trial is testing

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Who this might be right for
Neoplasm Metastasis
Pfizer 88
Testing effectiveness (Phase 2)Looking for participantsNCT07367516
What this trial is testing

Clinical Trial Evaluating TQB6411 Injection in Participant s With Esophageal Cancer

Who this might be right for
Esophageal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 105
Testing effectiveness (Phase 2)WithdrawnNCT05561491
What this trial is testing

ONCOS-102 in Combination With Other Novel Immune-therapies in Advanced Treatment-resistant Melanoma Patients

Who this might be right for
Melanoma
Targovax Oy
Testing effectiveness (Phase 2)Study completedNCT04681131
What this trial is testing

CAB-AXL-ADC Safety and Efficacy Study in Adults With NSCLC

Who this might be right for
Non-Small-Cell Lung Cancer
BioAtla, Inc. 85
Testing effectiveness (Phase 2)Looking for participantsNCT06698250
What this trial is testing

Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA)

Who this might be right for
Hepatocellular Carcinoma
Anwaar Saeed 40
Testing effectiveness (Phase 2)UnknownNCT05603013
What this trial is testing

Vinorelbine Metronomic Chemotherapy Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of Advanced Refractory Non-small Cell Lung Cancer and Breast Cancer(PRaG 6.0)

Who this might be right for
Carcinoma, Non-Small-Cell LungCarcinoma Breast
Second Affiliated Hospital of Soochow University 45
Large-scale testing (Phase 3)Study completedNCT04799249
What this trial is testing

Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Gemcitabine and Carboplatin for Metastatic Triple-Negative Breast Cancer (TNBC)

Who this might be right for
TNBC - Triple-Negative Breast CancerBreast Cancer
G1 Therapeutics, Inc. 194
Post-approval studies (Phase 4)Temporarily pausedNCT04036721
What this trial is testing

Coorticosteroid Regimen in Patients With Anti-PD-1/PD-L1 Induced Pneumonitis

Who this might be right for
Lung Neoplasm MalignantInterstitial Lung Disease
National Institute for Tuberculosis and Lung Diseases, Poland 85
Testing effectiveness (Phase 2)Study completedNCT03322540
What this trial is testing

Pembrolizumab Plus Epacadostat vs Pembrolizumab Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-654-05/ECHO-305-05)

Who this might be right for
Lung Cancer
Incyte Corporation 154
Not applicableLooking for participantsNCT04615988
What this trial is testing

Correlation Vitamin D Level to Endocrine Autoimmune Toxicity Due to Immune Checkpoint Inhibitors

Who this might be right for
ThyroidPD-1Cancer
Icahn School of Medicine at Mount Sinai 17
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