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Results for “PD-1/L1 Inhibitor”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT03616834
What this trial is testing

Tomivosertib (eFT-508) in Combination With PD-1/PD-L1 Inhibitor Therapy

Who this might be right for
Solid Tumors
Effector Therapeutics 39
Not applicableUnknownNCT03683407
What this trial is testing

Effect of Chemotherapy on TMB in NSCLC

Who this might be right for
Chemotherapy EffectImmunotherapyTumor Mutation Burden+1 more
Baodong Qin 30
Testing effectiveness (Phase 2)UnknownNCT03994744
What this trial is testing

Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC

Who this might be right for
Small-cell Lung CancerSmall Cell Lung CarcinomaSmall Cell Lung Cancer Recurrent+1 more
Hunan Cancer Hospital 68
Testing effectiveness (Phase 2)Study completedNCT02798406
What this trial is testing

Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects

Who this might be right for
Brain CancerBrain NeoplasmGlioma+8 more
DNAtrix, Inc. 49
Testing effectiveness (Phase 2)Study completedNCT03680521
What this trial is testing

Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma

Who this might be right for
Clear Cell Renal Cell Carcinoma
Mirati Therapeutics Inc. 25
Large-scale testing (Phase 3)Not Yet RecruitingNCT07790380
What this trial is testing

FH-006 Versus Investigator's Choice of Chemotherapy in Patients With Locally Advanced, Recurrent, or Metastatic Esophageal Squamous Cell Carcinoma Who Have Failed Prior PD-1/PD-L1 Inhibitor Combined With Platinum-Based Chemotherapy.

Who this might be right for
Locally Advanced, Recurrent or Metastatic ESCC Patients Who Have Failed Prior PD-1/PD-L1 Inhibitors Combined With Platinum-based Chemotherapy
Jiangsu HengRui Medicine Co., Ltd. 480
Post-approval studies (Phase 4)Looking for participantsNCT07744698
What this trial is testing

Metronomic Oral Paclitaxel Plus PD-1/ PD-L1 Inhibitor Maintenance in Advanced Lung Cancer (PULSE Study)

Who this might be right for
Squamous Non-Small Cell Lung Cancer sqNSCLCExtensive-stage Small Cell Lung Cancer (ES-SCLC)
Anhui Provincial Cancer Hospital 107
Testing effectiveness (Phase 2)Looking for participantsNCT05431270
What this trial is testing

Dose Escalation/Expansion Study of Mavrostobart (PT199), an Anti-CD73 mAb, Administered Alone and in Combination With a PD-1 Inhibitor or Chemotherapy (the MORNINGSTAR Study)

Who this might be right for
Non Small Cell Lung CancerPancreatic Ductal Adenocarcinoma
Phanes Therapeutics 40
Not applicableUnknownNCT04203095
What this trial is testing

Chromosomal Instability as a Surrogate Biomarker of Drug Resistance in Immunotherapy for Lung Cancer Patients

Who this might be right for
Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China 40
Early research (Phase 1)Ended earlyNCT03549000
What this trial is testing

A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies.

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)Triple Negative Breast Cancer (TNBC)Pancreatic Ductal Adenocarcinoma (PDAC)+4 more
Novartis Pharmaceuticals 127
Early research (Phase 1)Looking for participantsNCT06411691
What this trial is testing

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Who this might be right for
Colorectal CancerPancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 54
Testing effectiveness (Phase 2)Study completedNCT03085914
What this trial is testing

Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

Who this might be right for
Solid Tumor
Incyte Corporation 70
Testing effectiveness (Phase 2)WithdrawnNCT02535078
What this trial is testing

Phase 1b/2 Study of the Combination of IMCgp100 With Durvalumab and/or Tremelimumab in Advanced Cutaneous Melanoma

Who this might be right for
Malignant Melanoma
Immunocore Ltd
Large-scale testing (Phase 3)Looking for participantsNCT04966481
What this trial is testing

Palbociclib and Cetuximab Versus Cetuximab Monotherapy for Patients With CDKN2A-altered, HPV-unrelated Head and Neck Squamous Cell Carcinoma Who Experienced Disease Progression on a PD-1/L1 Inhibitor

Who this might be right for
HPV-unrelated Head and Neck Squamous Cell Carcinoma
Washington University School of Medicine 81
Not applicableStudy completedNCT04609930
What this trial is testing

Impact of Immune Checkpoint Inhibitor Therapy on Type 2 Inflammation

Who this might be right for
Patients Recieving Anti-PD-1 or Anti-PD-L1 Immunotherapies
University Hospital, Montpellier 143
Not applicableLooking for participantsNCT06635954
What this trial is testing

A Prospective Real World Evidence Study (PROWES) for Concordance Rate of Blood-based 3D Genome Conformation Mapping (Episwitch CiRT®) to Identify Likelihood of Response and Actual Response Rates to PD-(L)-1 Checkpoint Inhibitors Across Multiple Oncological Indications.

Who this might be right for
CancerImmunotherapyPD-1+2 more
Oxford Biodynamics Inc. 2,000
Testing effectiveness (Phase 2)UnknownNCT04239443
What this trial is testing

Clinical Study of PD-1 Monoclonal Antibody SHR-1210 and Apatinib in Advanced NSCLC, Soft Tissue Sarcoma, and Uterine Cancer

Who this might be right for
Advanced Non Small Cell Lung CancerUterine CancerSoft Tissue Sarcoma
Hunan Cancer Hospital 120
Early research (Phase 1)Active Not RecruitingNCT05878691
What this trial is testing

GRC 54276 in Participants With Advanced Solid Tumors and Lymphomas.

Who this might be right for
Advanced Solid TumorLymphoma
Glenmark Specialty S.A. 320
Testing effectiveness (Phase 2)Ended earlyNCT03116529
What this trial is testing

Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma
University of Maryland, Baltimore 22
Testing effectiveness (Phase 2)Study completedNCT04796194
What this trial is testing

Intratumoral Injection of LTX-315 in Combination With Pembrolizumab in Advanced Melanoma

Who this might be right for
Advanced Melanoma
Lytix Biopharma AS 23
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