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Results for “PD-L1 Negative”

140 trials

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Showing 20 of 140 results

Testing effectiveness (Phase 2)UnknownNCT03961698
What this trial is testing

Evaluation of IPI-549 Combined With Front-line Treatments in Pts. With Triple-Negative Breast Cancer or Renal Cell Carcinoma

Who this might be right for
Breast CancerRenal Cell Carcinoma
Infinity Pharmaceuticals, Inc. 91
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07244874
What this trial is testing

Sac-TMT Combined With Toripalimab for First-line Treatment of PD-L1 Positive a/mTNBC

Who this might be right for
TNBC - Triple-Negative Breast CancerPD-L1 Positive
Tianjin Medical University Cancer Institute and Hospital 41
Testing effectiveness (Phase 2)Study completedNCT02404441
What this trial is testing

Phase I/II Study of PDR001 in Patients With Advanced Malignancies

Who this might be right for
MelanomaNon-small Sell Lung Cancer (NSCLC)Triple Negative Breast Cancer+2 more
Novartis Pharmaceuticals 319
Testing effectiveness (Phase 2)Looking for participantsNCT06963905
What this trial is testing

Saci Nivo Rela for TNBC

Who this might be right for
Metastatic Triple-negative Breast Cancer
Yale University 60
Testing effectiveness (Phase 2)Temporarily pausedNCT05642195
What this trial is testing

Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung CancerNon-Small Cell Lung CarcinomaCarcinoma, Non-Small-Cell Lung+1 more
National Cancer Institute (NCI) 30
Large-scale testing (Phase 3)Active Not RecruitingNCT05382286
What this trial is testing

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

Who this might be right for
Triple Negative Breast CancerPD-L1 Positive
Gilead Sciences 443
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07134556
What this trial is testing

Phase II Trial Evaluating the Safety and Efficacy of the Combination of Zimberelimab, Domvanalimab and Sacituzumab Govitecan as 1L Therapy for PD-L1 Positive Advanced TNBC

Who this might be right for
Triple Negative Breast CancerPDL-1 Positive
MedSIR 25
Large-scale testing (Phase 3)Study completedNCT03675737
What this trial is testing

Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Participants Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-859/KEYNOTE-859)

Who this might be right for
Stomach Neoplasms
Merck Sharp & Dohme LLC 1,579
Testing effectiveness (Phase 2)Active Not RecruitingNCT04837209
What this trial is testing

Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer

Who this might be right for
Breast CancerTriple Negative Breast Cancer
Massachusetts General Hospital 32
Testing effectiveness (Phase 2)Looking for participantsNCT06793553
What this trial is testing

Induction Therapy of PTX+BV Followed by Atezolizumab+Nab-PTX for PD-L1+ TNBC

Who this might be right for
Metastatic Breast Cancer
Japan Breast Cancer Research Group 106
Testing effectiveness (Phase 2)Looking for participantsNCT07195734
What this trial is testing

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Recurrent Head and Neck Squamous Cell Carcinoma+15 more
National Cancer Institute (NCI)
Large-scale testing (Phase 3)Looking for participantsNCT07173751
What this trial is testing

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

Who this might be right for
Breast Neoplasms
BioNTech SE 558
Testing effectiveness (Phase 2)Study completedNCT03988036
What this trial is testing

A Study With Pembrolizumab in Combination With Dual Anti-HER2 Blockade With Trastuzumab and Pertuzumab in Early Breast Cancer Patients With Molecular HER2-enriched Intrinsic Subtype (Keyriched-1)

Who this might be right for
Breast Cancer
West German Study Group 46
Large-scale testing (Phase 3)Study completedNCT03125902
What this trial is testing

Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC)

Who this might be right for
Triple-Negative Breast Cancer
Hoffmann-La Roche 653
Testing effectiveness (Phase 2)WithdrawnNCT05233696
What this trial is testing

Radiotherapy in Combo With Chemo and Immunotherapy in Patients With PD-L1 Positive Metastatic TNBC

Who this might be right for
Triple Negative Breast CancerLocally Advanced Breast CancerUnresectable Breast Carcinoma+2 more
University of Colorado, Denver
Large-scale testing (Phase 3)Active Not RecruitingNCT03281954
What this trial is testing

Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo

Who this might be right for
Triple Negative Breast Cancer
NSABP Foundation Inc 1,550
Very early researchStudy completedNCT03132467
What this trial is testing

Durvalumab and Tremelimumab Before Surgery in Treating Patients With Hormone Receptor Positive, HER2 Negative Stage II-III Breast Cancer

Who this might be right for
Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIA Breast Cancer AJCC v8Anatomic Stage IIB Breast Cancer AJCC v8+14 more
M.D. Anderson Cancer Center 16
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05566223
What this trial is testing

CISH Inactivated TILs in the Treatment of NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell LungMetastatic Non Small Cell Lung CancerStage IV Non-small Cell Lung Cancer+3 more
Intima Bioscience, Inc. 70
Early research (Phase 1)Ended earlyNCT05069935
What this trial is testing

FT538 in Combination With Monoclonal Antibodies in Advanced Solid Tumors

Who this might be right for
Solid Tumor, Adult
Fate Therapeutics 16
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