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Results for “PD-L1 Positive”

189 trials

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Showing 20 of 189 results

Testing effectiveness (Phase 2)Looking for participantsNCT06579196
What this trial is testing

Trabedersen (OT-101) With Pembrolizumab for Newly Diagnosed Advanced NSCLC and Positive PD-L1

Who this might be right for
Non-small Cell Lung Cancer
University of Nebraska 45
Testing effectiveness (Phase 2)Study completedNCT02129556
What this trial is testing

Anti-PD-1 Monoclonal Antibody in Advanced, Trastuzumab-resistant, HER2-positive Breast Cancer

Who this might be right for
Metastatic Breast Cancer
ETOP IBCSG Partners Foundation 58
Testing effectiveness (Phase 2)UnknownNCT05115500
What this trial is testing

ADC Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of HER-2 Positive Advanced Solid Tumors(PRaG3.0)

Who this might be right for
CarcinomaSolid Tumor
Second Affiliated Hospital of Soochow University 55
Early research (Phase 1)Study completedNCT03812549
What this trial is testing

Safety and Tolerability Evaluation of Sintilimab in Combination With Radiation in Stage IV NSCLC Patients

Who this might be right for
Stage IV NSCLC
Sichuan University 29
Large-scale testing (Phase 3)Study completedNCT04148911
What this trial is testing

Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative Breast Cancer

Who this might be right for
Triple-Negative Breast Cancer
Hoffmann-La Roche 184
Testing effectiveness (Phase 2)UnknownNCT03994744
What this trial is testing

Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC

Who this might be right for
Small-cell Lung CancerSmall Cell Lung CarcinomaSmall Cell Lung Cancer Recurrent+1 more
Hunan Cancer Hospital 68
Testing effectiveness (Phase 2)Looking for participantsNCT06869473
What this trial is testing

Cetuximab Plus Platinum and Taxane-based Chemotherapy, Followed by Avelumab and Cetuximab, as First-line Treatment for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) Patients With a PD-L1 Combined Positive Score (CPS)≥1≤19.

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)Recurrent Head and Neck CancerMetastatic Head and Neck Cancer
Gruppo Oncologico del Nord-Ovest 67
Testing effectiveness (Phase 2)Active Not RecruitingNCT03260023
What this trial is testing

Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers

Who this might be right for
HPV-Related CarcinomaHPV-Related Cervical CarcinomaHPV-Related Anal Squamous Cell Carcinoma+2 more
Transgene 143
Testing effectiveness (Phase 2)Active Not RecruitingNCT05879822
What this trial is testing

Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

Who this might be right for
Advanced Solid Tumor
Incyte Corporation 73
Early research (Phase 1)Active Not RecruitingNCT04958239
What this trial is testing

Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

Who this might be right for
Neoplasms
Boehringer Ingelheim 151
Large-scale testing (Phase 3)Looking for participantsNCT06103864
What this trial is testing

A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer

Who this might be right for
Breast Cancer
AstraZeneca 625
Large-scale testing (Phase 3)Study completedNCT02369874
What this trial is testing

Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer

Who this might be right for
Recurrent or Metastatic PD-L1-positive or -Negative Squamous Cell Carcinoma of the Head and Neck SCCHN
AstraZeneca 736
Not applicableNot Yet RecruitingNCT07191405
What this trial is testing

Clinical Study of Chemotherapy and Immunotherapy Combined With Lactobacillus Johnsonii in Patients With Multiple Irresectable Solid Tumors

Who this might be right for
ImmunotherapyChemotherapy
Second Affiliated Hospital, School of Medicine, Zhejiang University 156
Testing effectiveness (Phase 2)Looking for participantsNCT05718323
What this trial is testing

Niraparib Added to Anti-PD-L1 Antibody Maintenance in SLFN11-positive, Extensive-disease SCLC

Who this might be right for
SCLC,Extensive StageSLFN11-positive
ETOP IBCSG Partners Foundation 44
Not applicableLooking for participantsNCT07038928
What this trial is testing

TReatment Approaches and bIomarkers preValence in bladdEr Cancer in RuSsian Federation

Who this might be right for
Bladder Cancer
AstraZeneca 600
Testing effectiveness (Phase 2)UnknownNCT03808857
What this trial is testing

A Study in Recurrent or Metastatic Cervical Cancer Patients With PD-L1 Positive

Who this might be right for
Cervical Cancer
Genor Biopharma Co., Ltd. 80
Testing effectiveness (Phase 2)WithdrawnNCT05566223
What this trial is testing

CISH Inactivated TILs in the Treatment of NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell LungMetastatic Non Small Cell Lung CancerStage IV Non-small Cell Lung Cancer+3 more
Intima Bioscience, Inc.
Testing effectiveness (Phase 2)UnknownNCT04940637
What this trial is testing

UNITO-001- Study in HRR/PDL1 Positive MPM/NSCLC

Who this might be right for
Lung CancerMesothelioma
University of Turin, Italy 70
Testing effectiveness (Phase 2)Study completedNCT04262856
What this trial is testing

Study to Evaluate Monotherapy and Combination Immunotherapies in Participants With PD-L1 Positive Non-small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung CancerNonsquamous Non Small Cell Lung CancerSquamous Non Small Cell Lung Cancer+1 more
Arcus Biosciences, Inc. 151
Testing effectiveness (Phase 2)Study completedNCT04300647
What this trial is testing

Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer

Who this might be right for
Cervical Cancer
Hoffmann-La Roche 172
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