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Results for “PD-L1-selected Solid Tumors”

28 trials

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Showing 20 of 28 results

Testing effectiveness (Phase 2)Study completedNCT05661578
What this trial is testing

Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors

Who this might be right for
PD-L1-selected Solid Tumors
Hoffmann-La Roche 64
Early research (Phase 1)Ended earlyNCT03665129
What this trial is testing

IPH5401 (Anti-C5aR) in Combination With Durvalumab in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Innate Pharma 73
Early research (Phase 1)Study completedNCT04242199
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099280 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+9 more
Incyte Corporation 182
Testing effectiveness (Phase 2)Looking for participantsNCT07523529
What this trial is testing

Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors

Who this might be right for
Advanced UnresectableMetastatic
Beijing Biotech 72
Testing effectiveness (Phase 2)Active Not RecruitingNCT05879822
What this trial is testing

Evaluate INCB099280 in Participants With Select Solid Tumors Who Are Immune Checkpoint Inhibitor Naive

Who this might be right for
Advanced Solid Tumor
Incyte Corporation 73
Testing effectiveness (Phase 2)Ended earlyNCT04629339
What this trial is testing

Study of INCB086550 in Select Solid Tumors

Who this might be right for
Non Small Cell Lung CancerUrothelial CancerRenal Cell Carcinoma+2 more
Incyte Corporation 16
Testing effectiveness (Phase 2)Ended earlyNCT04902040
What this trial is testing

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Who this might be right for
Advanced Bladder CarcinomaAdvanced Lung Non-Small Cell CarcinomaAdvanced Malignant Solid Neoplasm+32 more
M.D. Anderson Cancer Center 19
Early research (Phase 1)Looking for participantsNCT06487624
What this trial is testing

An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors

Who this might be right for
Advanced Solid TumorRefractory Hodgkin Lymphoma
FBD Biologics Limited 50
Testing effectiveness (Phase 2)Study completedNCT03861793
What this trial is testing

A Dose Escalation and Cohort Expansion Study of Subcutaneously-Administered Cytokine ALKS 4230 (Nemvaleukin Alfa) as a Single Agent and in Combination With Anti-PD-1 Antibody (Pembrolizumab) in Subjects With Select Advanced or Metastatic Solid Tumors (ARTISTRY-2)

Who this might be right for
Advanced Solid Tumors
Mural Oncology, Inc 116
Early research (Phase 1)Ended earlyNCT04272034
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+15 more
Incyte Corporation 105
Testing effectiveness (Phase 2)WithdrawnNCT05234606
What this trial is testing

A Safety and Preliminary Efficacy Study of SBT6290 Alone and in Combination With PD-(L)1 Inhibitors in Select Advanced Solid Tumors

Who this might be right for
Urothelial CarcinomaTriple Negative Breast CancerNon-small Cell Lung Cancer+2 more
Silverback Therapeutics
Large-scale testing (Phase 3)Looking for participantsNCT07044336
What this trial is testing

Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

Who this might be right for
Endometrial CancerMalignant Solid Tumour
AstraZeneca 800
Early research (Phase 1)Ended earlyNCT04458259
What this trial is testing

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Who this might be right for
Neoplasm Metastasis
Pfizer 88
Testing effectiveness (Phase 2)WithdrawnNCT04809012
What this trial is testing

Study of STI-3031 in Patients With Selected Relapsed or Refractory Solid Tumors

Who this might be right for
Solid TumorRefractory TumorRelapsed Solid Tumor
Sorrento Therapeutics, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT05877430
What this trial is testing

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

Who this might be right for
NSCLCHNSCCMelanoma+3 more
CJ Bioscience, Inc. 160
Early research (Phase 1)Study completedNCT02705482
What this trial is testing

Evaluate MEDI0562 in Combination With Immune Therapeutic Agents in Adult Subjects With Advanced Solid Tumors

Who this might be right for
Select Advanced Solid Tumors
MedImmune LLC 58
Early research (Phase 1)Study completedNCT03517488
What this trial is testing

XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Who this might be right for
MelanomaBreast CarcinomaHepatocellular Carcinoma+25 more
Xencor, Inc. 150
Early research (Phase 1)Study completedNCT03525795
What this trial is testing

ORIOn-E: A Study Evaluating CPI-1205 in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Constellation Pharmaceuticals 24
Testing effectiveness (Phase 2)Study completedNCT05383482
What this trial is testing

Afuresertib +Sintilimab+Chemotherapy in Patients With Selected Solid Tumors That Resistance to Prior Anti-PD-1/PD-L1

Who this might be right for
Solid TumorNSCLCCervical Cancer+3 more
Laekna Limited 22
Testing effectiveness (Phase 2)Study completedNCT05007106
What this trial is testing

MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)

Who this might be right for
Uterine Cervical NeoplasmsEndometrial NeoplasmsSquamous Cell Carcinoma of Head and Neck+8 more
Merck Sharp & Dohme LLC 613
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