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Results for “PDAC”

318 trials

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Showing 20 of 318 results

Testing effectiveness (Phase 2)Looking for participantsNCT05851924
What this trial is testing

NALIRIFOX in Combination With Radiation Therapy in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Who this might be right for
Pancreatic Ductal Adenocarcinoma
Memorial Sloan Kettering Cancer Center 60
Early research (Phase 1)Looking for participantsNCT05005403
What this trial is testing

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

Who this might be right for
Non-Small Cell Lung CancerHead and Neck Squamous Cell CarcinomaMicro Satellite Stable Colorectal Cancer+4 more
AbbVie
Not applicableStudy completedNCT06630481
What this trial is testing

Long-term Survival Outcomes According to the Pathologic Response After Neoadjuvant Treatment in PDAC and the Fate of the Patients with Good CAP Grade

Who this might be right for
Pancreatic CancerNeoadjuvant TherapyPathological Complete Response
Seoul National University Hospital 462
Large-scale testing (Phase 3)Looking for participantsNCT05314998
What this trial is testing

Adjuvant Trial in Patients With Resected PDAC Randomized to Allocation of Oxaliplatin- or Gemcitabine-based Chemotherapy by Standard Clinical Criteria or by a Transcriptomic Treatment Specific Stratification Signature

Who this might be right for
Pancreatic Ductal Adenocarcinoma
John Neoptolemos 394
Testing effectiveness (Phase 2)Looking for participantsNCT06937177
What this trial is testing

Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy

Who this might be right for
Cancer Weight Loss
Endevica Bio 120
Testing effectiveness (Phase 2)Looking for participantsNCT06128551
What this trial is testing

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal CancerPancreatic Ductal Adenocarcinoma
Revolution Medicines, Inc. 534
Early research (Phase 1)Active Not RecruitingNCT06147037
What this trial is testing

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Who this might be right for
Advanced Solid TumorMetastatic Colorectal CarcinomaHead and Neck Squamous Cell Carcinoma+4 more
AstraZeneca 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT04348045
What this trial is testing

Maintenance With Olaparib or Selumetinib + Durvaluma for m-PDAC Guided by BRCAness and KRAS Status.

Who this might be right for
Metastatic Pancreatic Adenocarcinoma
GERCOR - Multidisciplinary Oncology Cooperative Group 307
Not applicableLooking for participantsNCT07117045
What this trial is testing

Artificial Intelligence-powered Low-Dose Computed Tomography for Screening of Pancreatic Cancer

Who this might be right for
Pancreatic CancerIntraductal Papillary Mucinous NeoplasmHigh-grade Pancreatic Intraepithelial Neoplasia+2 more
Changhai Hospital 400,000
Post-approval studies (Phase 4)Looking for participantsNCT07262957
What this trial is testing

Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA)

Who this might be right for
Pancreas Head CancerPancreas AdenocarcinomaIPMN, Pancreatic+7 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 400
Testing effectiveness (Phase 2)Study completedNCT05222204
What this trial is testing

DDP ip Combined With AG in PDAC With Peritoneal Metastasis

Who this might be right for
Pancreatic Neoplasm
Fudan University 91
Testing effectiveness (Phase 2)UnknownNCT03487016
What this trial is testing

First-line Therapy in Metastatic PDAC

Who this might be right for
Metastatic Pancreatic Cancer
Ludwig-Maximilians - University of Munich 270
Testing effectiveness (Phase 2)Looking for participantsNCT07627711
What this trial is testing

Dual-Target CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma

Who this might be right for
Pancreatic Ductal Adenocarcinoma (PDAC)Unresectable Locally AdvancedMetastatic Disease
Beijing Biotech 42
Large-scale testing (Phase 3)Looking for participantsNCT07409272
What this trial is testing

Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Who this might be right for
Pancreatic CancerMetastatic Pancreatic CancerMetastatic Pancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc. 614
Very early researchStudy completedNCT02550327
What this trial is testing

Gemcitabine, Nab-Paclitaxel, Cisplatin and Anakinra Treatment on Patients With Pancreatic Cancer

Who this might be right for
Pancreatic Adenocarcinoma
Baylor Research Institute 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07685470
What this trial is testing

MRG003 With Gemcitabine for Second-line Advanced PDAC

Who this might be right for
Pancreatic Ductal Adenocarcinoma (PDAC)Second Line Treatment
Peking Union Medical College Hospital 30
Testing effectiveness (Phase 2)Ended earlyNCT06069778
What this trial is testing

Safety, Tolerability, and Efficacy of mFOLFIRINOX ± BNT321 as Adjuvant Therapy Following Curative Resection in Patients With Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic Cancer
BioNTech SE 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT04083599
What this trial is testing

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

Who this might be right for
Malignant Solid TumorNon-Small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)+3 more
Genmab 350
Testing effectiveness (Phase 2)Ended earlyNCT03637491
What this trial is testing

Avelumab, Binimetinib and Talazoparib in Patients With Locally Advanced or Metastatic RAS-mutant Solid Tumors

Who this might be right for
Pancreatic Cancer
Pfizer 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT05968326
What this trial is testing

The Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

Who this might be right for
Adenocarcinoma, Pancreatic Ductal
Genentech, Inc. 260
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