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Results for “PDL-1”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06502977
What this trial is testing

Study Evaluating Tarlatamab in Chinese Participants With Advanced Small Cell Lung Cancer After Two or More Prior Lines of Treatment

Who this might be right for
Extensive Stage Small Cell Lung Cancer
Amgen 32
Early research (Phase 1)Study completedNCT03908814
What this trial is testing

Phase I Clinical Trial of Human Anti-PD-L1 Antibody Injection (LDP) in Patients With Advanced Malignant Tumors

Who this might be right for
Advanced Tumors
Dragonboat Biopharmaceutical Company Limited 66
Testing effectiveness (Phase 2)Active Not RecruitingNCT06483334
What this trial is testing

Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab in Advanced Urothelial Carcinoma (MK-3475-04C/KEYMAKER-U04)

Who this might be right for
Metastatic Urothelial CarcinomaLocally Advanced Urothelial Carcinoma
Merck Sharp & Dohme LLC 38
Not applicableActive Not RecruitingNCT07448493
What this trial is testing

Local Treatment Strategies for Brain Metastases of Gastric and Esophageal Cancer

Who this might be right for
Gastric CancerEsophageal CancerBrain Metastases
Blokhin's Russian Cancer Research Center 230
Early research (Phase 1)Ended earlyNCT03948763
What this trial is testing

MRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001)

Who this might be right for
NeoplasmsCarcinoma, Non-Small-Cell LungPancreatic Neoplasms+1 more
Merck Sharp & Dohme LLC 70
Testing effectiveness (Phase 2)Study completedNCT05535569
What this trial is testing

Phase Ib/II Study to Evaluate the Safety and Efficacy of Nivolumab in Combination With Paclitaxel in Epstein-Barr Virus(EBV)-Related, or Microsatellite Instability-High (MSI-H), or Programmed Cell Death Ligand 1 (PD-L1) Positive Advanced Gastric Cancer

Who this might be right for
Recurrent/Metastatic Gastric Cancer
Yonsei University 50
Large-scale testing (Phase 3)Looking for participantsNCT06345729
What this trial is testing

Calderasib (MK-1084) Plus Pembrolizumab (MK-3475) in Participants With KRAS G12C Mutant Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-1084-004/KANDLELIT-004)

Who this might be right for
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 600
Large-scale testing (Phase 3)Not Yet RecruitingNCT07818070
What this trial is testing

A Trial of ONO-4578 Versus Placebo in Combination With Nivolumab and Chemotherapy in Participants With Gastric Cancer, Esophagogastric Junction Cancer, or Esophageal Adenocarcinoma

Who this might be right for
Gastric CancerEsophagogastric Junction CancerEsophageal Adenocarcinoma
Ono Pharmaceutical Co., Ltd. 600
Early research (Phase 1)Study completedNCT02350673
What this trial is testing

Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT06504394
What this trial is testing

Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Coformulated With Berahyaluronidase Alfa (MK-3475A) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL)(MK-3475A-F65)

Who this might be right for
Classical Hodgkin Lymphoma RecurrentClassical Hodgkin Lymphoma RefractoryPrimary Mediastinal Large B-cell Lymphoma Recurrent+1 more
Merck Sharp & Dohme LLC
Testing effectiveness (Phase 2)UnknownNCT04777162
What this trial is testing

Tislelizumab Plus Anlotinib for Immunotherapy Resistant Gastrointestinal Cancer

Who this might be right for
Gastric CancerColo-rectal Cancer
Peking University 40
Large-scale testing (Phase 3)Active Not RecruitingNCT04700124
What this trial is testing

Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-Eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

Who this might be right for
Bladder Cancer
Merck Sharp & Dohme LLC 808
Testing effectiveness (Phase 2)Active Not RecruitingNCT06041802
What this trial is testing

Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) (Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180)) in Japanese Participants With Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC) or Locally Advanced (LA) Unresectable cSCC (MK-3475A-E39)

Who this might be right for
Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 19
Testing effectiveness (Phase 2)Active Not RecruitingNCT06305767
What this trial is testing

A Clinical Study of Intismeran Autogene (V940) Treatment and Pembrolizumab in People With Bladder Cancer (V940-005/INTerpath-005)

Who this might be right for
Bladder Cancer
Merck Sharp & Dohme LLC 230
Testing effectiveness (Phase 2)Study completedNCT03829007
What this trial is testing

PD-L1 ImagiNg to prediCt Durvalumab Treatment Response in HNSCC

Who this might be right for
Head and Neck Cancer
Radboud University Medical Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT07367516
What this trial is testing

Clinical Trial Evaluating TQB6411 Injection in Participant s With Esophageal Cancer

Who this might be right for
Esophageal Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 105
Early research (Phase 1)Ended earlyNCT07159828
What this trial is testing

Assess AXN-2510 Treatment in Adult Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor, Adult
Axion Bio, Inc 3
Large-scale testing (Phase 3)Study completedNCT02926196
What this trial is testing

Adjuvant Treatment for High-risk Triple Negative Breast Cancer Patients With the Anti-PD-l1 Antibody Avelumab

Who this might be right for
Triple Negative Breast Neoplasms
Istituto Oncologico Veneto IRCCS 474
Testing effectiveness (Phase 2)WithdrawnNCT05561491
What this trial is testing

ONCOS-102 in Combination With Other Novel Immune-therapies in Advanced Treatment-resistant Melanoma Patients

Who this might be right for
Melanoma
Targovax Oy
Testing effectiveness (Phase 2)Active Not RecruitingNCT03474497
What this trial is testing

UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint Blockade

Who this might be right for
Non Small Cell Lung CancerMetastatic MelanomaMetastatic Renal Cell Carcinoma+1 more
Megan Daly, MD 18
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