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Results for “PDL-1”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Looking for participantsNCT06841354
What this trial is testing

Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Who this might be right for
Triple Negative Breast Neoplasms
Merck Sharp & Dohme LLC 1,000
Testing effectiveness (Phase 2)Ended earlyNCT02546986
What this trial is testing

Safety and Efficacy Study of CC-486 With MK-3475 to Treat Locally Advanced or Metastatic Non-small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Celgene 100
Early research (Phase 1)Study completedNCT04881045
What this trial is testing

Study to Test the Safety and Tolerability of PF-07257876 in Participants With Selected Advanced Tumors.

Who this might be right for
Non-Small Cell Lung CancerSquamous Cell Carcinoma of the Head and NeckOvarian Cancer
Pfizer 29
Large-scale testing (Phase 3)Active Not RecruitingNCT04929041
What this trial is testing

Testing the Addition of Radiation Therapy to the Usual Treatment (Immunotherapy With or Without Chemotherapy) for Advanced Stage Non-small Cell Lung Cancer Patients Who Are PD-L1 Negative

Who this might be right for
Lung AdenocarcinomaLung Adenosquamous CarcinomaLung Non-Small Cell Carcinoma+3 more
National Cancer Institute (NCI) 427
Testing effectiveness (Phase 2)Looking for participantsNCT06839066
What this trial is testing

A Phase II Study to Evaluate HLX43 in Subjects With Recurrent/Metastatic Nasopharyngeal Carcinoma Failed or Intolerance to Second-line Therapy

Who this might be right for
Nasopharyngeal Carcinoma (NPC)
Shanghai Henlius Biotech 70
Not applicableLooking for participantsNCT04481256
What this trial is testing

TGF-β And PDL-1 Inhibition in Esophageal Squamous Cell Carcinoma Combined With Chemoradiation TheRapY

Who this might be right for
Carcinoma, Squamous CellOesophageal Cancer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 49
Testing effectiveness (Phase 2)Study completedNCT02453594
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (MK-3475-087/KEYNOTE-087)

Who this might be right for
Hodgkin Lymphoma
Merck Sharp & Dohme LLC 211
Not applicableLooking for participantsNCT06772454
What this trial is testing

To Evaluate the Efficacy and Safety of Inhaled Corticosteroids Combined With Bronchodilators and Programmed Death-ligand 1 (PD-L1) Inhibitor Plus Platinum-based Chemotherapy in Patients With Advanced Lung Squamous Cell Carcinoma Complicated With Chronic Obstructive Pulmonary Disease (COPD)

Who this might be right for
Lung Cancer Squamous CellCOPD
Guangzhou Institute of Respiratory Disease 60
Early research (Phase 1)Ended earlyNCT05408871
What this trial is testing

Non-invasive Measurement of PD-L1 Levels With Positron Emission Tomography (PET) in Head and Neck Malignancies and Intracranial Metastases

Who this might be right for
Cancer Head NeckMetastatic CancerMetastatic Lung Cancer
Yale University 7
Testing effectiveness (Phase 2)UnknownNCT05115500
What this trial is testing

ADC Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of HER-2 Positive Advanced Solid Tumors(PRaG3.0)

Who this might be right for
CarcinomaSolid Tumor
Second Affiliated Hospital of Soochow University 55
Early research (Phase 1)Looking for participantsNCT07404332
What this trial is testing

5-Azacitidine Plus PD-1/PD-L1 Inhibitor With PD-1/PD-L1 Refractory Tumors

Who this might be right for
Solid TumorLocally Advanced Solid TumorMetastatic Tumor
Mohammed Milhem 35
Testing effectiveness (Phase 2)Looking for participantsNCT07020065
What this trial is testing

Reduced-dose Carboplatin-doublet-chemotherapy + Cemiplimab vs Cemiplimab Monotherapy in Treatment Naive Older and Frail Patients With Metastatic NSCLC With PD-L1 <50%

Who this might be right for
Metastatic NSCLC - Non-Small Cell Lung Cancer
Swiss Cancer Institute 156
Testing effectiveness (Phase 2)Study completedNCT02460198
What this trial is testing

Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Previously-Treated Locally Advanced Unresectable or Metastatic Colorectal Cancer (MK-3475-164/KEYNOTE-164)

Who this might be right for
Colorectal Carcinoma
Merck Sharp & Dohme LLC 124
Early research (Phase 1)Active Not RecruitingNCT05853367
What this trial is testing

Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)

Who this might be right for
Metastatic Solid TumorsAdvanced Solid Tumors
Merck Sharp & Dohme LLC 95
Testing effectiveness (Phase 2)Looking for participantsNCT07105592
What this trial is testing

Nimotuzumab Plus Adebrelimab With Chemotherapy in Cisplatin-Ineligible Patients With Head And Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Fudan University 68
Testing effectiveness (Phase 2)Active Not RecruitingNCT04895722
What this trial is testing

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).

Who this might be right for
Colorectal Cancer
Merck Sharp & Dohme LLC 302
Testing effectiveness (Phase 2)Active Not RecruitingNCT05599789
What this trial is testing

Pembrolizumab in Combination With Plinabulin and Docetaxel For Metastatic NSCLC After ICIs (KeyPemls-004)

Who this might be right for
Non Small Cell Lung Cancer Metastatic
Peking Union Medical College Hospital 47
Testing effectiveness (Phase 2)UnknownNCT06361927
What this trial is testing

A Phase II Study of SSGJ-707 Monotherapy in First-line PD-L1 Positive Advanced NSCLC Patients

Who this might be right for
NSCLC
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. 120
Early research (Phase 1)Active Not RecruitingNCT05354323
What this trial is testing

NECVAX-NEO1 in Addition to Checkpoint Inhibitor in Patients With Solid Tumors

Who this might be right for
Solid Tumors, Adult
NEC OncoImmunity AS 6
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07662720
What this trial is testing

A Phase II Trial for MOR Antagonism With Axelopran to Enhance Immunotherapy in Head and Neck Cancer

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)
Glycyx Therapeutics 18
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