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Results for “PDL-1”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT03382899
What this trial is testing

Study of Pegilodecakin (LY3500518) With Pembrolizumab Compared to Pembrolizumab Alone First-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung Cancer
Eli Lilly and Company 101
Early research (Phase 1)Study completedNCT04272944
What this trial is testing

MSB2311 in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Transcenta Therapeutics (Hangzhou) Co., Ltd. 42
Early research (Phase 1)WithdrawnNCT03982134
What this trial is testing

PDR001 + Panobinostat for Melanoma and NSCLC

Who this might be right for
MelanomaNon Small Cell Lung Cancer
Muhammad Furqan
Early research (Phase 1)WithdrawnNCT02868632
What this trial is testing

Study of Immune Checkpoint Inhibition With Radiation Therapy in Unresectable, Non-metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
NYU Langone Health
Not applicableNot Yet RecruitingNCT07051928
What this trial is testing

Study of Atezolizumab in Advanced Non-oncogene-addicted NSCLC With PD-L1 ≥50%, Including Longitudinal c-FLIP Assessment in Monocytic MDSCs.

Who this might be right for
Non Small Cell Lung Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 107
Large-scale testing (Phase 3)Active Not RecruitingNCT04956692
What this trial is testing

Study of Pembrolizumab (MK-3475) Subcutaneous (SC) Versus Pembrolizumab Intravenous (IV) Administered With Platinum Doublet Chemotherapy in Participants With Metastatic Squamous or Nonsquamous Non-Small Cell Lung Cancer (NSCLC) (MK-3475-A86)

Who this might be right for
Non-Small Cell Lung Cancer
Merck Sharp & Dohme LLC 531
Testing effectiveness (Phase 2)Active Not RecruitingNCT05180799
What this trial is testing

BA3071 in Patients With Solid Tumors

Who this might be right for
NSCLCMelanoma
BioAtla, Inc. 320
Large-scale testing (Phase 3)Active Not RecruitingNCT04380636
What this trial is testing

Study of Pembrolizumab With Concurrent Chemoradiation Therapy Followed by Pembrolizumab With or Without Olaparib in Stage III Non-Small Cell Lung Cancer (NSCLC) (MK-7339-012/KEYLYNK-012)

Who this might be right for
Lung NeoplasmsCarcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC 870
Testing effectiveness (Phase 2)Study completedNCT03707587
What this trial is testing

M7824 in People With Recurrent Respiratory Papillomatosis

Who this might be right for
Recurrent Respiratory PapillomatosisRespiratory PapillomatosisLaryngeal Papilloma, Recurrent+1 more
National Cancer Institute (NCI) 9
Early research (Phase 1)Study completedNCT05960240
What this trial is testing

Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.

Who this might be right for
Chronic Hepatitis b
Arbutus Biopharma Corporation 128
Testing effectiveness (Phase 2)Study completedNCT03797326
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

Who this might be right for
Advanced Solid TumorsTriple Negative Breast CancerOvarian Cancer+5 more
Merck Sharp & Dohme LLC 611
Post-approval studies (Phase 4)Study completedNCT04489888
What this trial is testing

Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
Merck Sharp & Dohme LLC 101
Large-scale testing (Phase 3)Looking for participantsNCT03486873
What this trial is testing

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Who this might be right for
Solid TumorsHematologic Malignancies
Merck Sharp & Dohme LLC 3,500
Early research (Phase 1)Looking for participantsNCT06084286
What this trial is testing

Dual-targeting CLDN18.2 and PD-L1 CAR-T for Patients with CLDN18.2-positive Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Sichuan University 29
Early research (Phase 1)WithdrawnNCT04955262
What this trial is testing

A CD8 Positron Emission Tomography With Computed Tomography (PET/CT) Study Using ⁸⁹Zr Df-IAB22M2C in Patients With Metastatic Melanoma Receiving Bempegaldesleukin (NKTR-214) and Nivolumab

Who this might be right for
Metastatic Melanoma
Nektar Therapeutics
Early research (Phase 1)Study completedNCT02791334
What this trial is testing

Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors

Who this might be right for
Solid TumorMicrosatellite Instability-High (MSI-H) Solid TumorsCutaneous Melanoma+2 more
Eli Lilly and Company 164
Testing effectiveness (Phase 2)Active Not RecruitingNCT05078931
What this trial is testing

Evaluate Pembrolizumab Plus Lenvatinib in PD-L1 Positive TKI Resistant NSCLC Patients

Who this might be right for
NSCLC
Shanghai Chest Hospital 35
Not applicableStudy completedNCT05387512
What this trial is testing

Real-world Association Between Concomitant Beta-blocker Exposure and Anti-PD-1/PD-L1 Treatment Outcomes in Advanced Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
Affiliated Hospital of Nantong University 60
Large-scale testing (Phase 3)Study completedNCT03833167
What this trial is testing

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

Who this might be right for
Carcinoma, Squamous Cell
Merck Sharp & Dohme LLC 450
Early research (Phase 1)Ended earlyNCT03746704
What this trial is testing

Study of ImmunoPet Imaging of PD-L1 in Tumors Using 89Zr-DFO-REGN3504 in Adult Participants With Advanced PD-L1 Positive Malignancies

Who this might be right for
Advanced PD-L1 Positive Malignancies
Regeneron Pharmaceuticals 2
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