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Results for “PDL-1”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT02130466
What this trial is testing

The Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With Trametinib and Dabrafenib in Participants With Advanced Melanoma (MK-3475-022/KEYNOTE-022)

Who this might be right for
MelanomaSolid Tumors
Merck Sharp & Dohme LLC 184
Testing effectiveness (Phase 2)Looking for participantsNCT07111520
What this trial is testing

A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

Who this might be right for
Non-small Cell Lung Cancer
BioNTech SE 880
Testing effectiveness (Phase 2)Looking for participantsNCT06339424
What this trial is testing

Atezolizumab and Bevacizumab With Photon Radiotherapy for Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Chang Gung Memorial Hospital 45
Testing effectiveness (Phase 2)Study completedNCT05008224
What this trial is testing

Study of Safety and Efficacy of Pembrolizumab and Chemotherapy in Participants With Newly Diagnosed Classical Hodgkin Lymphoma (cHL) (MK-3475-C11/KEYNOTE-C11)

Who this might be right for
Classical Hodgkin Lymphoma
Merck Sharp & Dohme LLC 146
Large-scale testing (Phase 3)Ended earlyNCT04066491
What this trial is testing

Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC

Who this might be right for
Biliary Tract CancerCholangiocarcinomaGallbladder Cancer
EMD Serono Research & Development Institute, Inc. 309
Early research (Phase 1)Ended earlyNCT05393713
What this trial is testing

Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8MelanomaMetastatic Melanoma+1 more
Mayo Clinic 3
Not applicableNot Yet RecruitingNCT05661110
What this trial is testing

Biomarker Analysis of HIPEC Combined With PD1/PDL1 Inhibitor for Gastric Cancer With Peritoneal Metastasis

Who this might be right for
Gastric Cancer
Affiliated Cancer Hospital & Institute of Guangzhou Medical University 46
Early research (Phase 1)Looking for participantsNCT07096882
What this trial is testing

SDTM001 Injection as Adjuvant Therapy for NSCLC Patients After Radical Surgical Resection

Who this might be right for
Non-Small Cell Lung Cancer
Cytocraft Biopharmaceutical Co., Ltd. 22
Large-scale testing (Phase 3)Study completedNCT05523323
What this trial is testing

Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (MK-7902-010/LEAP-010)-China Extension

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Merck Sharp & Dohme LLC 112
Early research (Phase 1)Study completedNCT03495323
What this trial is testing

Prexasertib (LY2606368), CHK1 Inhibitor, and LY3300054, PD-L1 Inhibitor, in Patients With Advanced Solid Tumors

Who this might be right for
Cancer
Dana-Farber Cancer Institute 17
Not applicableActive Not RecruitingNCT05091190
What this trial is testing

Immunotherapy Clearance and Phenotype of Circulating Tumor Cells in Lung and Head and Neck Cancers

Who this might be right for
Metastatic NSCLCMetastatic Head and Neck Cancer
Hospices Civils de Lyon 75
Testing effectiveness (Phase 2)Study completedNCT03162224
What this trial is testing

Safety and Efficacy of MEDI0457 and Durvalumab in Participants With Human Papilloma Virus (HPV) Associated Recurrent/Metastatic Head and Neck Cancer

Who this might be right for
Head and Neck CancerHuman Papilloma Virus
MedImmune LLC 35
Early research (Phase 1)Active Not RecruitingNCT05382325
What this trial is testing

MK-1484 as Monotherapy and in Combination With Pembrolizumab (MK-3475) In Advanced or Metastatic Solid Tumors (MK-1484-001)

Who this might be right for
Advanced or Metastatic Solid Tumors
Merck Sharp & Dohme LLC 70
Testing effectiveness (Phase 2)Study completedNCT03083808
What this trial is testing

Phase II Trial of Continuation Therapy in Advanced NSCLC

Who this might be right for
Non-Small-Cell Lung Cancer
Greg Durm, MD 35
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06881017
What this trial is testing

Establishment of Precision Targeted Therapy Strategies for Advanced Gastric Cancer Based on Novel Molecular Subtyping

Who this might be right for
Gastric CancerHER2 + Gastric CancerCLDN18.2-positive Adenocarcinoma of the Gastroesophageal Junction+1 more
China Medical University, China 140
Early research (Phase 1)Study completedNCT02616640
What this trial is testing

Determine Dose and Regimen of Durvalumab as Monotherapy or in Combination With Pomalidomide With or Without Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma

Who this might be right for
Multiple Myeloma
Celgene 114
Large-scale testing (Phase 3)Study completedNCT02702401
What this trial is testing

Study of Pembrolizumab (MK-3475) vs. Best Supportive Care in Participants With Previously Systemically Treated Advanced Hepatocellular Carcinoma (MK-3475-240/KEYNOTE-240)

Who this might be right for
Hepatocellular Carcinoma
Merck Sharp & Dohme LLC 413
Not applicableStudy completedNCT03092739
What this trial is testing

Assess Programmed Death Ligand-1 (PD-L1) Expression in Cytological Versus Histological Lung Cancer Specimens

Who this might be right for
Carcinoma, Non-Small-Cell LungCarcinoma, Small Cell
Hoffmann-La Roche 184
Testing effectiveness (Phase 2)UnknownNCT03991975
What this trial is testing

Study of TQB2450 Combined With Anlotinib in Subjects With Advanced Acral Malignant Melanoma

Who this might be right for
Advanced Acral Malignant Melanoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 42
Testing effectiveness (Phase 2)Study completedNCT03179436
What this trial is testing

Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)

Who this might be right for
Advanced Solid Tumors
Merck Sharp & Dohme LLC 415
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