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Results for “PDL-1”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT04334759
What this trial is testing

DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesothelioma

Who this might be right for
MesotheliomaPleural MesotheliomaMalignant Pleural Mesothelioma
PrECOG, LLC. 214
Testing effectiveness (Phase 2)Study completedNCT03833661
What this trial is testing

M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)

Who this might be right for
Biliary Tract CancerCholangiocarcinomaGallbladder Cancer
EMD Serono Research & Development Institute, Inc. 159
Testing effectiveness (Phase 2)Active Not RecruitingNCT05994001
What this trial is testing

Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standard of Chemotherapy and PD1/PD-L1 Antibody

Who this might be right for
Biliary Tract CancerCandonilimabClaudin 18.2
Shanghai Zhongshan Hospital 78
Early research (Phase 1)Study completedNCT02812875
What this trial is testing

CA-170 (Oral PD-L1, PD-L2 and VISTA Checkpoint Antagonist) in Patients With Advanced Tumors and Lymphomas

Who this might be right for
Advanced Solid Tumors or Lymphomas
Curis, Inc. 71
Testing effectiveness (Phase 2)UnknownNCT05862831
What this trial is testing

Clinical Study of PM1003 in Phase I/IIa Treatment of Advanced Malignant Solid Tumors

Who this might be right for
Advanced Solid Tumors
Biotheus Inc. 285
Very early researchLooking for participantsNCT06305962
What this trial is testing

177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors

Who this might be right for
PDL1 Gene MutationNon Small Cell Lung CancerSmall Cell Lung Cancer ( SCLC )+6 more
Radiopharm Theranostics, Ltd 30
Early research (Phase 1)Looking for participantsNCT05338658
What this trial is testing

Study of PAT in Patients With Solid Tumor Cancers

Who this might be right for
MetastasisSolid Tumor
Masonic Cancer Center, University of Minnesota 21
Early research (Phase 1)Study completedNCT03010176
What this trial is testing

Study of Ulevostinag (MK-1454) Alone or in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors or Lymphomas (MK-1454-001)

Who this might be right for
Solid TumorsLymphoma
Merck Sharp & Dohme LLC 156
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07416058
What this trial is testing

PHOENIX: QL1706 Plus Chemotherapy and Bevacizumab in AGA-Resistant, PD-L1 ≥50% Non-Squamous NSCLC

Who this might be right for
Lung Adenocarcinoma
Guangdong Association of Clinical Trials 61
Testing effectiveness (Phase 2)Study completedNCT05661578
What this trial is testing

Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors

Who this might be right for
PD-L1-selected Solid Tumors
Hoffmann-La Roche 64
Testing effectiveness (Phase 2)Study completedNCT04665843
What this trial is testing

Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
Hoffmann-La Roche 123
Testing effectiveness (Phase 2)Active Not RecruitingNCT05565378
What this trial is testing

A Platform Study of Novel Immunotherapy Combinations in Participants With Previously Untreated, Advanced/Metastatic Non-Small-Cell Lung Cancer

Who this might be right for
Lung Cancer, Non-Small Cell
GlaxoSmithKline 351
Testing effectiveness (Phase 2)UnknownNCT04164745
What this trial is testing

Efficacy and Safety Study of Anlotinib With Pembrolizumab in Adults With Programmed Cell Death-Ligand 1 (PD-L1)-Positive Treatment-naïve Non-small Cell Lung Cancer

Who this might be right for
NSCLC
Peking Union Medical College Hospital 49
Large-scale testing (Phase 3)Not Yet RecruitingNCT07633873
What this trial is testing

SYS6010 Combined With Enlonstobart Versus Immunotherapy+ Platinum-based Chemotherapy for Patients With PD-L1-Positive Locally Advanced or Metastatic NSCLC（SYNSTAR 04）

Who this might be right for
Non-Small Cell Lung Cancer
CSPC Megalith Biopharmaceutical Co.,Ltd. 500
Early research (Phase 1)Active Not RecruitingNCT05334329
What this trial is testing

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

Who this might be right for
Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell Carcinoma+8 more
University of California, Irvine 6
Not applicableLooking for participantsNCT05878977
What this trial is testing

Biomarkers in Immunotherapy of Melanoma

Who this might be right for
Metastatic MelanomaImmune Checkpoints InhibitorsGastrointestinal Microbiome (Bacterial and Viral)+1 more
Institute of Oncology Ljubljana 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT03600701
What this trial is testing

Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaRefractory Lung Non-Small Cell Carcinoma+1 more
National Cancer Institute (NCI) 53
Testing effectiveness (Phase 2)Study completedNCT04428151
What this trial is testing

Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) vs. Standard Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed After Platinum Therapy and Immunotherapy (MK-7902-009/E7080-G000-228/LEAP-009)

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
Merck Sharp & Dohme LLC 408
Testing effectiveness (Phase 2)UnknownNCT04980690
What this trial is testing

Clinical Trial of IBC0966 in Patients With Advanced Malignant Tumors

Who this might be right for
Advanced Malignant Tumors
SUNHO（China）BioPharmaceutical CO., Ltd. 228
Testing effectiveness (Phase 2)Active Not RecruitingNCT02849496
What this trial is testing

Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Locally Advanced Unresectable Breast Carcinoma+1 more
National Cancer Institute (NCI) 89
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