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Results for “PDL-1 Positive”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT04515979
What this trial is testing

Vactosertib in Combination with Pembrolizumab for PD-L1 Positive Non-small Cell Lung Cancer (NSCLC) Subjects

Who this might be right for
Carcinoma, Non-Small-Cell Lung
MedPacto, Inc. 11
Large-scale testing (Phase 3)Ended earlyNCT04738487
What this trial is testing

Coformulation of Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab (MK-3475) Monotherapy for Programmed Cell Death 1 Ligand 1 (PD-L1) Positive Metastatic Non-Small Cell Lung Cancer (MK-7684A-003, KEYVIBE-003)

Who this might be right for
Lung NeoplasmsNon-Small-Cell Lung Carcinoma
Merck Sharp & Dohme LLC 1,264
Testing effectiveness (Phase 2)Looking for participantsNCT06016920
What this trial is testing

Safety and Efficacy of VB10.16 and Pembrolizumab in Patients With Head-Neck Squamous Cell Carcinoma

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell CarcinomaHNSCC
Nykode Therapeutics ASA 110
Large-scale testing (Phase 3)Not Yet RecruitingNCT07763171
What this trial is testing

Paclitaxel, Ramucirumab and Tislelizumab Switch Maintenance in Advanced HER2-negative and PD-L1 TAP Score of 5 or More Advanced Gastroesophageal Adenocarcinoma

Who this might be right for
Gastroesophageal Adenocarcinoma
Gruppo Oncologico del Nord-Ovest 244
Testing effectiveness (Phase 2)Study completedNCT01846416
What this trial is testing

Atezolizumab in Participants With Programmed Death-Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [FIR]

Who this might be right for
Non-Small Cell Lung Cancer
Genentech, Inc. 138
Testing effectiveness (Phase 2)Study completedNCT03891238
What this trial is testing

Avelumab as Single Agent in Metastatic or Locally Advanced Urothelial Cancer in Patients Unfit for Cisplatin. The ARIES Study

Who this might be right for
Metastatic or Locally Advanced PD-L1 Positive Urothelial Cancer
Consorzio Oncotech 67
Early research (Phase 1)Study completedNCT02605915
What this trial is testing

Safety and Pharmacokinetics of Atezolizumab Combination Treatments in Participants With HER2-Positive and HER2-Negative Breast Cancer

Who this might be right for
HER2-Positive Metastatic Breast CancerHER2-Negative Metastatic Breast CancerLocally Advanced or Early Breast Cancer
Hoffmann-La Roche 98
Testing effectiveness (Phase 2)UnknownNCT05115500
What this trial is testing

ADC Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of HER-2 Positive Advanced Solid Tumors(PRaG3.0)

Who this might be right for
CarcinomaSolid Tumor
Second Affiliated Hospital of Soochow University 55
Testing effectiveness (Phase 2)UnknownNCT06361927
What this trial is testing

A Phase II Study of SSGJ-707 Monotherapy in First-line PD-L1 Positive Advanced NSCLC Patients

Who this might be right for
NSCLC
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07662720
What this trial is testing

A Phase II Trial for MOR Antagonism With Axelopran to Enhance Immunotherapy in Head and Neck Cancer

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)
Glycyx Therapeutics 18
Testing effectiveness (Phase 2)Looking for participantsNCT07400302
What this trial is testing

Sintilimab Combined With Chemotherapy for Adjuvant Treatment of Mucosal Melanoma After Surgery

Who this might be right for
Mucosal MelanomaPD-L1 Positive
The First Hospital of Jilin University 220
Testing effectiveness (Phase 2)Looking for participantsNCT04198766
What this trial is testing

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Who this might be right for
Solid TumorNon-Small Cell Lung CancerHead and Neck Cancer+5 more
Inhibrx Biosciences, Inc 340
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06881017
What this trial is testing

Establishment of Precision Targeted Therapy Strategies for Advanced Gastric Cancer Based on Novel Molecular Subtyping

Who this might be right for
Gastric CancerHER2 + Gastric CancerCLDN18.2-positive Adenocarcinoma of the Gastroesophageal Junction+1 more
China Medical University, China 140
Large-scale testing (Phase 3)Study completedNCT03615326
What this trial is testing

Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811)

Who this might be right for
Gastric NeoplasmsGastroesophageal Junction Adenocarcinoma
Merck Sharp & Dohme LLC 738
Large-scale testing (Phase 3)Active Not RecruitingNCT04660344
What this trial is testing

Atezolizumab Versus Placebo as Adjuvant Therapy in Participants With High-risk Muscle-invasive Bladder Cancer (MIBC) Who Are ctDNA Positive Following Cystectomy

Who this might be right for
Muscle-invasive Bladder Cancer
Hoffmann-La Roche 761
Not applicableStudy completedNCT03732560
What this trial is testing

A Comparison of Nivolumab-based Treatments in a Real-world PD-L1 Positive Metastatic Melanoma Population in the US

Who this might be right for
Melanoma
Bristol-Myers Squibb 600
Testing effectiveness (Phase 2)UnknownNCT04940637
What this trial is testing

UNITO-001- Study in HRR/PDL1 Positive MPM/NSCLC

Who this might be right for
Lung CancerMesothelioma
University of Turin, Italy 70
Large-scale testing (Phase 3)Active Not RecruitingNCT03725059
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

Who this might be right for
Breast Cancer
Merck Sharp & Dohme LLC 1,240
Not applicableUnknownNCT05527808
What this trial is testing

A Single-arm Exploratory Study of Neoadjuvant Therapy

Who this might be right for
Lung Adenocarcinoma
Jun Liu 28
Large-scale testing (Phase 3)Active Not RecruitingNCT04534205
What this trial is testing

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

Who this might be right for
Unresectable Head and Neck Squamous Cell CarcinomaMetastatic Head and Neck CancerRecurrent Head and Neck Cancer
BioNTech SE 358
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