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Results for “PDL1- Colorectal Carcinoma”

69 trials

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Showing 20 of 69 results

Large-scale testing (Phase 3)Study completedNCT04157985
What this trial is testing

Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsNSCLCBladder Cancer+10 more
Dan Zandberg 161
Not applicableNot Yet RecruitingNCT06682247
What this trial is testing

A Real-world Study of Chidamide in Combination with PD-1/PD-L1 Antibodies and Anti-angiogenic Agents in Advanced MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Feng Wang 200
Testing effectiveness (Phase 2)Study completedNCT05061017
What this trial is testing

Pixatimod (PG545) Plus Nivolumab in PD-1 Relapsed/Refractory Metastatic Melanoma and NSCLC and With Nivolumab and Low-dose Cyclophosphamide in MSS Metastatic Colorectal Carcinoma (mCRC)

Who this might be right for
NSCLCMetastatic Colorectal CarcinomaRefractory Melanoma
Diwakar Davar 13
Not applicableStudy completedNCT02475889
What this trial is testing

Hepatic RFA Increases T Cell Infiltraion and PD-L1 Expression in Primary Colorecatl Cancer

Who this might be right for
Colorectal Cancer
The First People's Hospital of Changzhou 78
Testing effectiveness (Phase 2)Ended earlyNCT02982694
What this trial is testing

Study With Atezolizumab Plus Bevacizumab in Patients With Chemotherapy Resistant, MSI-like, Colorectal Cancer

Who this might be right for
MSIColoRectal CancerChemotherapy+1 more
Vall d'Hebron Institute of Oncology 46
Testing effectiveness (Phase 2)Looking for participantsNCT06948448
What this trial is testing

Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer
Ono Pharmaceutical Co., Ltd. 144
Early research (Phase 1)Active Not RecruitingNCT05787587
What this trial is testing

PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsBreast CancerOvarian Cancer+6 more
IDEAYA Biosciences 216
Early research (Phase 1)Ended earlyNCT04060342
What this trial is testing

GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic AdenocarcinomaEsophageal AdenocarcinomaEsophageal Squamous Cell Carcinoma+11 more
GB006, Inc., a wholly owned subsidiary of Gossamer Bio, Inc. 61
Early research (Phase 1)Ended earlyNCT04458259
What this trial is testing

Study of PF-07265807 in Participants With Metastatic Solid Tumors.

Who this might be right for
Neoplasm Metastasis
Pfizer 88
Early research (Phase 1)Looking for participantsNCT06012734
What this trial is testing

LB-100 (PP2A Inhibitor) and Atezolizumab (PD-L1 Inhibitor) in Metastatic Colorectal Cancer Patients

Who this might be right for
Metastatic Microsatellite-stable Colorectal Cancer
The Netherlands Cancer Institute 37
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Not applicableUnknownNCT05692895
What this trial is testing

PDL1 In Primary Colorectal Carcinoma and Its Prognostic Impact

Who this might be right for
PDL1- Colorectal Carcinoma
Sohag University 60
Testing effectiveness (Phase 2)Looking for participantsNCT05187338
What this trial is testing

Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors

Who this might be right for
Lung CancerLiver CancerColorectal Cancer+8 more
Second Affiliated Hospital of Guangzhou Medical University 100
Early research (Phase 1)Ended earlyNCT04108481
What this trial is testing

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticColon CancerMetastatic Colorectal Cancer+7 more
University of Iowa 5
Testing effectiveness (Phase 2)Looking for participantsNCT07106892
What this trial is testing

Phase II, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of HLX43 (an Anti-PD-L1 ADC) in Subjects With Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer (CRC)
Shanghai Henlius Biotech 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04895722
What this trial is testing

Evaluation of Co-formulated Pembrolizumab/Quavonlimab (MK-1308A) Versus Other Treatments in Participants With Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Stage IV Colorectal Cancer (CRC) (MK-1308A-008/KEYSTEP-008).

Who this might be right for
Colorectal Cancer
Merck Sharp & Dohme LLC 302
Testing effectiveness (Phase 2)Active Not RecruitingNCT04230759
What this trial is testing

Radiochemotherapy +/- Durvalumab for Locally-advanced Anal Carcinoma. A Multicenter, Randomized, Phase II Trial of the German Anal Cancer Study Group

Who this might be right for
Anal CancerAnal CarcinomaAnal Cancer Stage III+1 more
Goethe University 180
Large-scale testing (Phase 3)Study completedNCT05600309
What this trial is testing

Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)-China Extension Study

Who this might be right for
Colorectal Cancer
Merck Sharp & Dohme LLC 94
Testing effectiveness (Phase 2)Study completedNCT02460198
What this trial is testing

Study of Pembrolizumab (MK-3475) as Monotherapy in Participants With Previously-Treated Locally Advanced Unresectable or Metastatic Colorectal Cancer (MK-3475-164/KEYNOTE-164)

Who this might be right for
Colorectal Carcinoma
Merck Sharp & Dohme LLC 124
Testing effectiveness (Phase 2)Ended earlyNCT04442126
What this trial is testing

NM21-1480 in Adult Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorNon-small Cell Lung CancerColorectal Cancer+6 more
Numab Therapeutics AG 52
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