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Results for “PFIC1”

32 trials

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Showing 20 of 32 results

Not applicableLooking for participantsNCT06777914
What this trial is testing

Familial Intrahepatic Cholestasis-related Genes Associated with Disease Susceptibility in Hepato-biliary Cancers

Who this might be right for
Hepatobiliary CancersProgressive Familial Intrahepatic Cholestasis (PFIC)Cholestatic Liver Disease
IRCCS Azienda Ospedaliero-Universitaria di Bologna 600
Not applicableLooking for participantsNCT07317193
What this trial is testing

DEFINING THE GENETIC DRIVERS OF ADULT-ONSET CHOLESTATIC LIVER DISEASE

Who this might be right for
Cholestatic Liver DiseaseProgressive Familial Intrahepatic Cholestasis
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 60
Large-scale testing (Phase 3)Study completedNCT04185363
What this trial is testing

An Extension Study of Maralixibat in Patients With Progressive Familial Intrahepatic Cholestasis (PFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Mirum Pharmaceuticals, Inc. 90
Not applicableUnknownNCT05704517
What this trial is testing

Progressive Familial Intrahepatic Cholestasis in Indian Children - Establishing an Indian PFIC Registry

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
Institute of Liver and Biliary Sciences, India 200
Not applicableLooking for participantsNCT06778174
What this trial is testing

Prospective Analysis of the Treatment of Progressive Familial Intrahepatic Cholestasis (TreatFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
University Medical Center Groningen 200
Not applicableStudy completedNCT02131623
What this trial is testing

Validation of the Itch Reported Outcome (ItchRO) Diaries in Pediatric Cholestatic Liver Disease

Who this might be right for
Alagille SyndromeProgressive Familial Intrahepatic Cholestasis
Mirum Pharmaceuticals, Inc. 23
Large-scale testing (Phase 3)WithdrawnNCT03353454
What this trial is testing

A Placebo-controlled Study of Maralixibat (SHP625) in Pediatric Subjects With Progressive Familial Intrahepatic Cholestasis (PFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Mirum Pharmaceuticals, Inc.
Not applicableLooking for participantsNCT07185919
What this trial is testing

The Effectiveness, Safety and the Long-term Outcomes of Participants With Progressive Familial Intrahepatic Cholestasis (PFIC) Who Take Odevixibat (Bylvay) in South Korea

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
Ipsen 10
Not applicableNo Longer AvailableNCT02094222
What this trial is testing

Expanded Access Protocol for an Intermediate Size Population - RAVICTI for Byler Disease

Who this might be right for
Byler Disease
Robert Squires, Jr.
Testing effectiveness (Phase 2)Study completedNCT04729751
What this trial is testing

Evaluate the Safety and Tolerability of Maralixibat in Infant Participants With Cholestatic Liver Diseases Including Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille Syndrome (ALGS).

Who this might be right for
Progressive Familial Intrahepatic CholestasisAlagille SyndromeCholestatic Liver Disease
Mirum Pharmaceuticals, Inc. 27
Large-scale testing (Phase 3)Study completedNCT03566238
What this trial is testing

This Study Will Investigate the Efficacy and Safety of A4250 in Children With PFIC Types 1 or 2

Who this might be right for
PFIC1PFIC2
Albireo 62
Not applicableStudy completedNCT05687474
What this trial is testing

Baby Detect : Genomic Newborn Screening

Who this might be right for
Congenital Adrenal HyperplasiaFamilial Hyperinsulinemic Hypoglycemia 1Phosphoglucomutase 1 Deficiency+121 more
Centre Hospitalier Universitaire de Liege 6,824
Not applicableLooking for participantsNCT06781242
What this trial is testing

Genotype-phenotype Relationship Between Cryptogenic Cholestasis and Familial Intrahepatic Cholestasis

Who this might be right for
Cholestatic Liver DiseaseIntrahepatic CholestasisProgressive Familial Intrahepatic Cholestasis+1 more
IRCCS Azienda Ospedaliero-Universitaria di Bologna 300
Large-scale testing (Phase 3)Study completedNCT05543187
What this trial is testing

TAK-625 for the Treatment of Progressive Familial Intrahepatic Cholestasis (PFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Takeda 5
Not applicableApproved For MarketingNCT04483531
What this trial is testing

Odevixibat for the Treatment of Progressive Familial Intrahepatic Cholestasis

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
Albireo
Early research (Phase 1)Study completedNCT02963077
What this trial is testing

A Safety and Pharmakokinetic Study of A4250 Alone or in Combination With A3384

Who this might be right for
Orphan Cholestatic Liver DiseasesPrimary Biliary CirrhosisProgressive Familial Intrahepatic Cholestasis+1 more
Albireo 94
Large-scale testing (Phase 3)Study completedNCT03905330
What this trial is testing

Evaluate the Efficacy and Safety of Maralixibat in Subjects With Progressive Familial Intrahepatic Cholestasis (MARCH-PFIC)

Who this might be right for
Progressive Familial Intrahepatic Cholestasis (PFIC)
Mirum Pharmaceuticals, Inc. 93
Early research (Phase 1)Study completedNCT03082937
What this trial is testing

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Who this might be right for
Orphan Cholestatic Liver DiseasesProgressive Familial Intrahepatic CholestasisAlagille Syndrome+1 more
Albireo 6
Not applicableNot Yet RecruitingNCT07411716
What this trial is testing

Pediatric Evaluation and Registry for Liver Cholestasis in Canada

Who this might be right for
PFIC - Progressive Familial Intrahepatic CholestasisAlagille Syndrome (ALGS)Cholestasis, Intrahepatic
Children's Hospital of Eastern Ontario 220
Large-scale testing (Phase 3)Study completedNCT03659916
What this trial is testing

Long Term Safety & Efficacy Study Evaluating The Effect of A4250 in Children With PFIC

Who this might be right for
Progressive Familial Intrahepatic Cholestasis
Albireo, an Ipsen Company 116
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