Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “PK, PD, and Safety”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Early research (Phase 1)Study completedNCT02705469
What this trial is testing

ZEN003694 in Patients With Metastatic Castration-Resistant Prostate Cancer

Who this might be right for
Metastatic Castration-Resistant Prostate Cancer
Zenith Epigenetics 44
Early research (Phase 1)Study completedNCT06893796
What this trial is testing

Safety, Tolerability, and PK/PD of Telpegfilgrastim in Premenopausal Non-pregnant Females

Who this might be right for
Preeclampsia
Xiamen Amoytop Biotech Co., Ltd. 18
Testing effectiveness (Phase 2)Study completedNCT01018979
What this trial is testing

Safety and PK/PD of TG-0054 in Multiple Myeloma, Non-Hodgkin Lymphoma and Hodgkin Disease Patients

Who this might be right for
Multiple MyelomaNon-Hodgkin LymphomaHodgkin Disease
GPCR Therapeutics, Inc. 19
Early research (Phase 1)Ended earlyNCT03501069
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Single and Multiple Oral Dose of TAK-418 in Healthy Female Participants

Who this might be right for
Healthy Volunteers
Millennium Pharmaceuticals, Inc. 32
Testing effectiveness (Phase 2)WithdrawnNCT03266159
What this trial is testing

A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD), and Clinical Activity of GSK525762 Plus Trametinib in Subjects With Solid Tumors

Who this might be right for
Solid Tumours
GlaxoSmithKline
Testing effectiveness (Phase 2)UnknownNCT01364155
What this trial is testing

Safety, Tolerability, PK, and PD of LIM-0705 in Subjects With Impaired Glucose Tolerance or Abnormal HOMA-IR

Who this might be right for
Impaired Glucose ToleranceInsulin Resistance
Limerick BioPharma 50
Early research (Phase 1)Study completedNCT06361355
What this trial is testing

Study of CMAB807 Post-change in Manufacturing Site and Prolia in Healthy Volunteers

Who this might be right for
Healthy Volunteers
Taizhou Mabtech Pharmaceutical Co.,Ltd 128
Early research (Phase 1)Study completedNCT04229433
What this trial is testing

The Multiple Dose of PK/PD Study of SHR2285 Tablets in Healthy Subjects

Who this might be right for
Thrombus
Jiangsu HengRui Medicine Co., Ltd. 36
Not applicableNot Yet RecruitingNCT07476378
What this trial is testing

Evaluate MTM-H-001 Injection in Adult Participants With Relapsed or Refractory B-cell Malignancies

Who this might be right for
Lymphoma, Large B-Cell, Diffuse (DLBCL)Lymphoma, FollicularLymphoma, Mantle-Cell+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 69
Early research (Phase 1)Study completedNCT01940133
What this trial is testing

Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of PQR309

Who this might be right for
Advanced Solid Tumors
PIQUR Therapeutics AG 28
Testing effectiveness (Phase 2)Study completedNCT02455011
What this trial is testing

Dose Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of REMD-477 in Subjects With Type 2 Diabetes Mellitus

Who this might be right for
Type 2 Diabetes MellitusDiabetes
REMD Biotherapeutics, Inc. 75
Testing effectiveness (Phase 2)Ended earlyNCT05124210
What this trial is testing

Pharmacokinetics, Pharmacodynamics, and Safety of Single-dose Sotrovimab in High-risk Pediatric Participants With Mild to Moderate COVID-19

Who this might be right for
COVID-19
GlaxoSmithKline 8
Early research (Phase 1)Study completedNCT04389775
What this trial is testing

To Evaluate the Safety, Tolerability, PK, and PD of XW003 Injection in Healthy Adult Participants

Who this might be right for
Type 2 Diabetes MellitusObesityNonalcoholic Steatohepatitis
Sciwind Biosciences APAC CO Pty. Ltd. 64
Early research (Phase 1)Study completedNCT04415671
What this trial is testing

Phase 1 Safety, Tolerability, PK & PD Study of AD-214 Administered to Healthy Volunteers

Who this might be right for
Interstitial Lung Disease
AdAlta Limited 50
Not applicableStudy completedNCT06153498
What this trial is testing

PK/PD Properties and Safety of Remazolam Besylate for Injection in ICU Patients With Impaired Renal Function

Who this might be right for
Mechanically Ventilated Patients
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 36
Testing effectiveness (Phase 2)Study completedNCT01494610
What this trial is testing

Pharmacokinetic and Pharmacodynamic (PK and PD) Study of Fluticasone Propionate and Salmeterol Combination Product Delivered in a Capsule-based Inhaler and in a Multi-dose Dry Powder Inhaler in Moderate Asthma Patients and Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Patients.

Who this might be right for
Asthma
GlaxoSmithKline 60
Early research (Phase 1)UnknownNCT04703374
What this trial is testing

Compare PK, PD and Safety of CKD-382 in Healthy Subjects

Who this might be right for
GERD
Chong Kun Dang Pharmaceutical 48
Early research (Phase 1)Study completedNCT03431610
What this trial is testing

A Phase 1b Study Assessing the PK, PD, Safety & Tolerability of SB414 in Atopic Dermatitis

Who this might be right for
Atopic Dermatitis
Novan, Inc. 48
Early research (Phase 1)Study completedNCT05298787
What this trial is testing

SAD/MAD Study of RLS-0071 in Healthy Volunteers in Support of a COVID-19 Development Program

Who this might be right for
Healthy Volunteer
ReAlta Life Sciences, Inc. 56
Testing effectiveness (Phase 2)Looking for participantsNCT03878849
What this trial is testing

Investigation of the Anti-tumor Effect of 2X-121 in Patients With Recurrent, Advanced Ovarian Cancer

Who this might be right for
Advanced Ovarian Cancer
Allarity Therapeutics 40
Next Page