Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “PK, PD, and Safety”

Showing 20 of 0 results

Early research (Phase 1)Study completedNCT05232396
What this trial is testing

Clinical Study of Single Dose IL-6R mAb Injection in RA Patients

Who this might be right for
Rheumatoid Arthritis
Beijing VDJBio Co., LTD. 40
Early research (Phase 1)Study completedNCT03061981
What this trial is testing

Evaluate The Safety,Tolerability, PK and PD Of DA-1241 In Healthy Male Subjects

Who this might be right for
Diabetes Mellitus, Type 2
Dong-A ST Co., Ltd. 60
Early research (Phase 1)Study completedNCT01081158
What this trial is testing

Safety, Tolerability, PK and PD of SCH 900518 in Naive or Treatment-Experienced Subjects Infected With HCV Genotype 1 (Protocol No. P04695)

Who this might be right for
Hepatitis C, Chronic
Merck Sharp & Dohme LLC 41
Early research (Phase 1)Study completedNCT05351047
What this trial is testing

Assess Safety, Tolerability, PK and PD of AZD2373 in Healthy Male Participants of Sub-Saharan West African Ancestry

Who this might be right for
Healthy Volunteers
AstraZeneca 24
Testing effectiveness (Phase 2)Study completedNCT01597635
What this trial is testing

The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury

Who this might be right for
Lung Injury, Acute
GlaxoSmithKline 44
Testing effectiveness (Phase 2)Study completedNCT01236404
What this trial is testing

Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Study to Assess Safety, Tolerability, PK and PD Response of PB1023 Injection Following Single and Multiple SQ Doses in Adults With Type 2 Diabetes Mellitus

Who this might be right for
Diabetes Mellitus, Type 2
PhaseBio Pharmaceuticals Inc. 80
Early research (Phase 1)Study completedNCT06945458
What this trial is testing

Safety, PK, PD, and Clinical Activity of Orally Administered KT-621 in Adult Patients With Atopic Dermatitis (AD)

Who this might be right for
Atopic Dermatitis
Kymera Therapeutics, Inc. 22
Early research (Phase 1)Study completedNCT01760187
What this trial is testing

Phase I Study of the Safety, Tolerability, PK & PD of Lomitapide in Japanese and Caucasian Subjects With Elevated LDL-C

Who this might be right for
Healthy Volunteer
Aegerion Pharmaceuticals, Inc. 72
Testing effectiveness (Phase 2)Study completedNCT02130193
What this trial is testing

Investigation of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Efficacy of Oral Danirixin in Symptomatic COPD Subjects With Mild to Moderate Airflow Limitation at Risk for Exacerbations

Who this might be right for
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline 102
Testing effectiveness (Phase 2)Study completedNCT01943851
What this trial is testing

A Dose Escalation Study to Investigate the Safety, Pharmacokinetics (PK), Pharmacodynamics (PD) and Clinical Activity of GSK525762 in Subjects With Relapsed, Refractory Hematologic Malignancies

Who this might be right for
Neoplasms
GlaxoSmithKline 111
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06798675
What this trial is testing

Phase 2a Study for PK/PD of nC-001

Who this might be right for
CHRONIC HYPONATREMIA
nephCentric 24
Early research (Phase 1)Study completedNCT02742766
What this trial is testing

Safety, Tolerability and Preliminary Pharmacokinetics (PK) and Pharmacodynamics (PD) of Single and Repeat Oral Doses of GSK3008356 in Healthy and Obese Subjects

Who this might be right for
Healthy Volunteers
GlaxoSmithKline 104
Testing effectiveness (Phase 2)Study completedNCT01319019
What this trial is testing

A 4-week Dose-Ranging, Dose-Interval, Efficacy, Safety and Tolerability Study of GSK961081 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Who this might be right for
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline 437
Testing effectiveness (Phase 2)Looking for participantsNCT05876312
What this trial is testing

Safety, Tolerability, PK and PD of ADX-038 in Healthy Participants and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
ADARx Pharmaceuticals, Inc. 50
Testing effectiveness (Phase 2)Study completedNCT02581657
What this trial is testing

Study to Assess the Safety, Tolerability, PK and PD Response of PE0139 Injection in Adult Subjects With T2DM

Who this might be right for
Type 2 Diabetes Mellitus
PhaseBio Pharmaceuticals Inc. 37
Early research (Phase 1)Active Not RecruitingNCT06205628
What this trial is testing

Safety, Tolerability, PK and PD of ADX-850 in Participants With Hypertension

Who this might be right for
HypertensionHypertension,Essential
ADARx Pharmaceuticals, Inc. 28
Early research (Phase 1)Study completedNCT02036645
What this trial is testing

SAD/MAD Study to Assess Safety, Tolerability, PK & PD of MEDI1814 in Subjects With Mild-Moderate Alzheimer's Disease.

Who this might be right for
Mild-Moderate Alzheimer's DiseaseHealthy Elderly
AstraZeneca 77
Testing effectiveness (Phase 2)Ended earlyNCT03781414
What this trial is testing

Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Liver Transplant Recipients With Additional 12-month Follow-up and Long-term Extension

Who this might be right for
Liver Transplant Rejection
Novartis Pharmaceuticals 129
Early research (Phase 1)Study completedNCT00479349
What this trial is testing

Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531

Who this might be right for
Alzheimer Disease
Wyeth is now a wholly owned subsidiary of Pfizer 32
Testing effectiveness (Phase 2)Looking for participantsNCT06300307
What this trial is testing

Study of ATX-01 in Participants With DM1

Who this might be right for
Myotonic Dystrophy 1
ARTHEx Biotech S.L. 56
Next Page

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation