Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “PK, PD, and Safety”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT06750276
What this trial is testing

Evaluate the Safety, Tolerability, PK, and PD Effects of AZD2389 in Participants With Liver Fibrosis and Compensated Cirrhosis.

Who this might be right for
Liver FibrosisHepatic Cirrhosis
AstraZeneca 40
Testing effectiveness (Phase 2)Study completedNCT05284617
What this trial is testing

Exploratory Ph 2A, Double-Blind, Placebo-Controlled Dose Escalation Study of Safety, Tolerability, PD, & PK of HU6 for Subjects With Obese HFpEF

Who this might be right for
Heart Failure With Preserved Ejection Fraction
Rivus Pharmaceuticals, Inc. 67
Early research (Phase 1)Looking for participantsNCT07462780
What this trial is testing

A Phase I Clinical Trial to Evaluate CMS-D017 Following Single and Multiple Doses in Healthy Participants

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria, PNHComplement-mediated Kidney Disease
Shenzhen Kangzhe Biotechnology Co., Ltd. 88
Early research (Phase 1)Study completedNCT03781947
What this trial is testing

Parenterally-administered Teverelix TFA in Healthy Male Volunteers

Who this might be right for
Healthy
Antev Ltd. 48
Early research (Phase 1)Study completedNCT00905138
What this trial is testing

First-in-Human Single Ascending and Multiple Dose of GLPG0259

Who this might be right for
Healthy
Lakefront Biotherapeutics NV 32
Testing effectiveness (Phase 2)Study completedNCT01498185
What this trial is testing

BMS - Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Dapagliflozin in Type 1 Diabetes

Who this might be right for
Type 1 Diabetes Mellitus
AstraZeneca 171
Large-scale testing (Phase 3)Study completedNCT00600808
What this trial is testing

Sustained Release Formulation of Somatropin (rDNA Origin)for Injection

Who this might be right for
Growth Hormone Deficiency
BioPartners GmbH 51
Testing effectiveness (Phase 2)Looking for participantsNCT07161258
What this trial is testing

A Pharmacokinetics (PK), Pharmacodynamics (PD), Safety and Tolerability Study of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (RMS)

Who this might be right for
Relapsing Multiple Sclerosis
Hoffmann-La Roche 12
Early research (Phase 1)Study completedNCT05594043
What this trial is testing

MK-6598 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-6598-001)

Who this might be right for
Advanced or Metastatic Solid Tumors
Merck Sharp & Dohme LLC 39
Large-scale testing (Phase 3)Active Not RecruitingNCT05196035
What this trial is testing

Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

Who this might be right for
Chronic Kidney DiseaseProteinuria
Bayer 219
Testing effectiveness (Phase 2)Ended earlyNCT01033019
What this trial is testing

To Evaluate the Safety, Local Tolerability, PK and PD of LDE225 on Sporadic Superficial and Nodular Skin Basal Cell Carcinomas (sBCC)

Who this might be right for
Sporadic Superficial and Nodular Skin Basal Cell Carcinomas
Novartis Pharmaceuticals 25
Early research (Phase 1)Study completedNCT03693950
What this trial is testing

The Study of PK, PD, Safety of Multiple Intravenous Injections of BCD-066 and Aranesp in Healthy Volunteers

Who this might be right for
Healthy
Biocad 57
Early research (Phase 1)Study completedNCT05433844
What this trial is testing

To Evaluate the PK, PD, Safety and Drug Tolerance in Healthy Volunteers

Who this might be right for
Healthy
JW Pharmaceutical 44
Early research (Phase 1)Study completedNCT01313065
What this trial is testing

Evaluation of Safety, Tolerability, PK & PD of Intravenous VX15/2503 in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumors
Vaccinex Inc. 42
Early research (Phase 1)UnknownNCT04727164
What this trial is testing

Study Investigating Safety,Tolerability,Pharmacokinetics and Antitumor Activities of HBM4003 Combine With Toripalimab

Who this might be right for
Solid Tumors
Harbour BioMed (Guangzhou) Co. Ltd. 61
Early research (Phase 1)Study completedNCT03646721
What this trial is testing

Evaluate the Safety, Tolerability, PK and PD of DA-1241 in Healthy Male Subjects and Subjects With T2DM

Who this might be right for
Diabetes Mellitus, Type 2
Dong-A ST Co., Ltd. 108
Early research (Phase 1)UnknownNCT05024305
What this trial is testing

Safety, Tolerability, PK, PD, Immunogenicity and Efficacy of TWP-102 in Patients With Advanced Malignancies.

Who this might be right for
Advanced Malignancies
Shandong TheraWisdom Biopharma Co., Ltd. 81
Early research (Phase 1)Study completedNCT02616861
What this trial is testing

Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers

Who this might be right for
Healthy
Cyclerion Therapeutics 54
Early research (Phase 1)Study completedNCT06435442
What this trial is testing

PK,PD and DDI of Epaminurad and Naproxen in Healthy Volunteers

Who this might be right for
Healthy
JW Pharmaceutical 57
Early research (Phase 1)Study completedNCT03855696
What this trial is testing

Investigate the Safety, Tolerability, PK and PD of MG1113 in Healthy Subjects and Hemophilia Patients

Who this might be right for
Hemophilia
Green Cross Corporation 41
Next Page