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Results for “PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)”

8 trials

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Showing 8 of 8 results

Early research (Phase 1)Looking for participantsNCT05885412
What this trial is testing

A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)

Who this might be right for
PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)
Rocket Pharmaceuticals Inc. 9
Testing effectiveness (Phase 2)Temporarily pausedNCT06275893
What this trial is testing

IC14 (Atibuclimab) in Arrhythmogenic Cardiomyopathy

Who this might be right for
Arrhythmogenic Right Ventricular DysplasiaArrhythmogenic Left Ventricular CardiomyopathyArrhythmogenic Right Ventricular Cardiomyopathy 1+4 more
Implicit Bioscience 5
Not applicableLooking for participantsNCT06976606
What this trial is testing

Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM

Who this might be right for
Arrhythmogenic CardiomyopathyPKP2-ACMPKP2-ARVC
Lexeo Therapeutics 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT06109181
What this trial is testing

Gene Therapy for ACM Due to a PKP2 Pathogenic Variant

Who this might be right for
Arrhythmogenic CardiomyopathyPKP2-ACMPKP2-ARVC
Lexeo Therapeutics 10
Not applicableLooking for participantsNCT06311708
What this trial is testing

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)

Who this might be right for
Arrhythmogenic Right Ventricular Cardiomyopathy
Tenaya Therapeutics 200
Not applicableEnrolling By InvitationNCT07050160
What this trial is testing

Long-term Follow-up Study of Gene Therapy for Arrhythmogenic Cardiomyopathy Due to a Plakophilin-2 Pathogenic Variant

Who this might be right for
Arrhythmogenic CardiomyopathyPKP2-ACMPKP2-ARVC
Lexeo Therapeutics 10
Early research (Phase 1)Looking for participantsNCT06228924
What this trial is testing

Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC

Who this might be right for
Arrhythmogenic Right Ventricular Cardiomyopathy
Tenaya Therapeutics 15
Not applicableLooking for participantsNCT06644742
What this trial is testing

PKP2-ACM Natural History Study

Who this might be right for
CardiomyopathiesHeart DiseasesCardiovascular Diseases+1 more
Rocket Pharmaceuticals Inc. 36