Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “PLS”

23 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 23 results

Not applicableActive Not RecruitingNCT04875416
What this trial is testing

Phenotype, Genotype and Biomarkers 2

Who this might be right for
Amyotrophic Lateral SclerosisHereditary Spastic ParaplegiaPrimary Lateral Sclerosis+2 more
University of Miami 217
Testing effectiveness (Phase 2)Looking for participantsNCT07174115
What this trial is testing

Evaluate the Efficacy and Safety of HTMC0658 Tablets in the Treatment of Chronic Rhinosinusitis Without Nasal Polyps

Who this might be right for
Chronic Sinusitis Without Nasal Polyps
Shanghai Yidian Pharmaceutical Technology Development Co., Ltd. 30
Not applicableStudy completedNCT01116934
What this trial is testing

Cytokines in Papillon-Lefèvre Syndrome

Who this might be right for
Papillon-Lefevre Disease
Goethe University 17
Not applicableStudy completedNCT02795897
What this trial is testing

Genomic Translation for Amyotrophic Lateral Sclerosis Care

Who this might be right for
ALS
Columbia University 254
Not applicableWithdrawnNCT00887835
What this trial is testing

A Post-Market Study of Transfacet Lumbar Spine Fixation and Fusion Utilizing the PERPOS™ PLS System

Who this might be right for
Lumbar Facet Disease
Interventional Spine, Inc.
Not applicableStudy completedNCT02663011
What this trial is testing

Language Error Type Evaluation in Developmental Delay Preschool Children by PLS-C

Who this might be right for
Language Error Type
Taipei Medical University Hospital 54
Not applicableWithdrawnNCT04055532
What this trial is testing

Biomarkers in Neurodegenerative Diseases

Who this might be right for
Mild Cognitive Impairment (MCI)Alzheimer Disease (AD)Dementia With Lewy Bodies (DLB)+8 more
University of Minnesota
Not applicableActive Not RecruitingNCT05271435
What this trial is testing

Digital Tools for Assessment of Motor Functions and Falls in ALS

Who this might be right for
ALSPLSPMA
Milton S. Hershey Medical Center 20
Not applicableLooking for participantsNCT07224256
What this trial is testing

VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration

Who this might be right for
Tetraplegia/TetraparesisQuadriplegiaCervical Spinal Cord Injury+4 more
Neuralink Corp 6
Early research (Phase 1)Study completedNCT03929068
What this trial is testing

Sinemet for Spasticity and Function in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis

Who this might be right for
Amyotrophic Lateral SclerosisMotor Neuron Disease
Washington University School of Medicine 15
Not applicableStudy completedNCT00071435
What this trial is testing

Brain Function in Primary Lateral Sclerosis

Who this might be right for
Motor Neuron Disease
National Institute of Neurological Disorders and Stroke (NINDS) 36
Not applicableNo Longer AvailableNCT04825613
What this trial is testing

"Individual Patient Expanded Access IND to Treat Primary Lateral Sclerosis"

Who this might be right for
Primary Lateral Sclerosis, Adult, 1
Hope Biosciences Research Foundation
Testing effectiveness (Phase 2)Ended earlyNCT03196375
What this trial is testing

Assess FLX-787 in Subjects With Motor Neuron Disease Experiencing Muscle Cramps.

Who this might be right for
Motor Neuron Disease
Flex Pharma, Inc. 54
Not applicableWithdrawnNCT01459302
What this trial is testing

Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders

Who this might be right for
Amyotrophic Lateral SclerosisFrontotemporal DementiaPLS+7 more
University of Massachusetts, Worcester
Not applicableStudy completedNCT00821132
What this trial is testing

Genetics of Familial and Sporadic ALS

Who this might be right for
Amyotrophic Lateral Sclerosis (ALS)Familial Amyotrophic Lateral SclerosisALS With Frontotemporal Dementia (ALS/FTD)+4 more
Northwestern University 13,521
Not applicableStudy completedNCT01143428
What this trial is testing

Oxidative Stress in Motor Neuron Disease: COSMOS Add-On Study

Who this might be right for
Motor Neuron DiseasePrimary Lateral Sclerosis
National Institute of Neurological Disorders and Stroke (NINDS) 10
Not applicableLooking for participantsNCT07187388
What this trial is testing

Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease.

Who this might be right for
Amyotrophic Lateral Sclerosis (ALS)Primary Lateral Sclerosis (PLS)Motor Neuron Disease, Amyotrophic Lateral Sclerosis
Nova Southeastern University 10
Not applicableStudy completedNCT00334516
What this trial is testing

Brain Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis

Who this might be right for
Cerebral Cortex Dysfunction
National Institute of Neurological Disorders and Stroke (NINDS) 77
Not applicableUnknownNCT03849235
What this trial is testing

A Pathophysiological Study of the Postprandial Human Liver (PLS)

Who this might be right for
CirrhosisFatty Liver
Copenhagen University Hospital, Hvidovre 60
Not applicableStudy completedNCT00362362
What this trial is testing

Collection of Blood Samples for DNA in Motor Neuron Disease

Who this might be right for
Motor Neuron Diseases
National Institute of Neurological Disorders and Stroke (NINDS) 23
Load More Results