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Results for “PMBCL”

43 trials

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Showing 20 of 43 results

Early research (Phase 1)Active Not RecruitingNCT06014762
What this trial is testing

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Who this might be right for
Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedHigh-grade B-cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
Poseida Therapeutics, Inc. 120
Early research (Phase 1)Looking for participantsNCT05995015
What this trial is testing

4SCAR19U T Cells Targeting B Cell Malignancies

Who this might be right for
B Cell Malignancies
Shenzhen Geno-Immune Medical Institute 30
Testing effectiveness (Phase 2)Looking for participantsNCT07249905
What this trial is testing

Dose Escalation and Dose Expansion Study of MDX2003 in Patients With Different Types of Lymphoma

Who this might be right for
LymphomaWaldenström Macroglobulinemia (WM)DLBCL - Diffuse Large B Cell Lymphoma+5 more
ModeX Therapeutics, An OPKO Health Company 180
Testing effectiveness (Phase 2)Looking for participantsNCT05934448
What this trial is testing

Pembro Plus CAR T-cell Therapy in R/R in PMBCL

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)Primary Mediastinal Large B Cell LymphomaPrimary Mediastinal Large B-Cell Lymphoma Refractory+3 more
Jennifer Crombie, MD 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT03625037
What this trial is testing

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

Who this might be right for
DLBCLHigh-grade B-cell Lymphoma (HGBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+6 more
Genmab 666
Early research (Phase 1)Enrolling By InvitationNCT07168486
What this trial is testing

CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas

Who this might be right for
B-Cell LymphomaDiffuse Large B Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
University of Maryland, Baltimore 15
Early research (Phase 1)Active Not RecruitingNCT04526834
What this trial is testing

Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma

Who this might be right for
Anaplastic Large Cell LymphomaPeripheral T Cell LymphomaExtranodal NK/T-cell Lymphoma+2 more
Tessa Therapeutics 21
Early research (Phase 1)Ended earlyNCT03893682
What this trial is testing

CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaNon-Hodgkin's Lymphoma
Aptose Biosciences Inc. 36
Testing effectiveness (Phase 2)UnknownNCT06412068
What this trial is testing

A Prospective Study: Sintilimab and R-CHOP in PMBCL Treatment

Who this might be right for
Primary Mediastinal Large B Cell Lymphoma
Sun Yat-sen University 32
Testing effectiveness (Phase 2)Study completedNCT04875195
What this trial is testing

Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68)

Who this might be right for
Hodgkin's LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)
Merck Sharp & Dohme LLC 66
Not applicableNot Yet RecruitingNCT07463781
What this trial is testing

Neurocognitive Assessment in Adults Undergoing CD19 Targeted CAR-T Cell Therapy

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)High Grade B Cell LymphomaPrimary Mediastinal B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 100
Early research (Phase 1)Active Not RecruitingNCT04049513
What this trial is testing

ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)

Who this might be right for
Lymphomas Non-Hodgkin's B-CellDiffuse Large B-cell Lymphoma (DLBCL)Primary Mediastinal B-cell Lymphoma (PMBCL)+3 more
Malaghan Institute of Medical Research 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05583149
What this trial is testing

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Who this might be right for
Refractory Aggressive B-cell LymphomasRefractory B-Cell Non-Hodgkin LymphomaAggressive B-cell NHL+10 more
Patrick C. Johnson, MD 28
Not applicableStudy completedNCT05130489
What this trial is testing

CAR T Cell Therapy Related Cardiovascular Outcomes

Who this might be right for
Cardiovascular DiseasesB-cell Acute Lymphoblastic LeukemiaB-cell Lymphoma Refractory+5 more
University College London Hospitals 150
Not applicableStudy completedNCT05162170
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma (PMBCL): Multicenter Retrospective Study

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 633
Testing effectiveness (Phase 2)Looking for participantsNCT06486051
What this trial is testing

WZTL-002 CAR T-cells for Adults With Relapsed Large B-cell Lymphoma

Who this might be right for
Large B-cell LymphomaDiffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+1 more
Malaghan Institute of Medical Research 60
Testing effectiveness (Phase 2)Study completedNCT03610724
What this trial is testing

Phase II Open Label Trial to Determine Safety & Efficacy of Tisagenlecleucel in Pediatric Non-Hodgkin Lymphoma Patients

Who this might be right for
Non-Hodgkin Lymphoma
Novartis Pharmaceuticals 34
Testing effectiveness (Phase 2)Active Not RecruitingNCT04745559
What this trial is testing

Optimizing Cellular and Humoral Immunity by Vaccinating With PCV13 Before and After CAR-T Therapy

Who this might be right for
Diffuse Large-Cell LymphomaPrimary Mediastinal Large B-Cell Lymphoma (PMBCL)Transformed Follicular Lymphoma (TFL)+2 more
H. Lee Moffitt Cancer Center and Research Institute 26
Testing effectiveness (Phase 2)Looking for participantsNCT05826535
What this trial is testing

Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

Who this might be right for
Relapsed Non-Hodgkin LymphomaRefractory Non-Hodgkin LymphomaNon-Hodgkin Lymphoma+1 more
Lyell Immunopharma, Inc. 270
Early research (Phase 1)Looking for participantsNCT06208735
What this trial is testing

CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies

Who this might be right for
B-Cell LeukemiaNon-Hodgkin's LymphomaB-cell Acute Lymphoblastic Leukemia+5 more
British Columbia Cancer Agency 24
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