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Results for “PMBCL”

46 trials

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Showing 20 of 46 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03625037
What this trial is testing

First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma

Who this might be right for
DLBCLHigh-grade B-cell Lymphoma (HGBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+6 more
Genmab 666
Testing effectiveness (Phase 2)UnknownNCT04705129
What this trial is testing

Zanubrutinib Combined With Tislelizumab in the Treatment of r/r PMBCL and EBV+ DLBCL

Who this might be right for
Primary Mediastinal Large B Cell LymphomaEBV-Positive DLBCL, Nos
Ruijin Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT04186520
What this trial is testing

CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies

Who this might be right for
Non Hodgkin Lymphoma (NHL)Mantle Cell Lymphoma (MCL)Chronic Lymphocytic Leukemia (CLL)+5 more
Medical College of Wisconsin 100
Testing effectiveness (Phase 2)Looking for participantsNCT06533579
What this trial is testing

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaLarge B-cell LymphomaChronic Lymphocytic Leukemia+10 more
Vironexis Biotherapeutics Inc. 32
Early research (Phase 1)Active Not RecruitingNCT06014762
What this trial is testing

P-CD19CD20-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With B Cell Malignancies

Who this might be right for
Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedHigh-grade B-cell LymphomaPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+7 more
Poseida Therapeutics, Inc. 120
Testing effectiveness (Phase 2)Looking for participantsNCT06486051
What this trial is testing

Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphoma

Who this might be right for
Large B-cell LymphomaDiffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedPrimary Mediastinal Large B-cell Lymphoma (PMBCL)+1 more
Malaghan Institute of Medical Research 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT05583149
What this trial is testing

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Who this might be right for
Refractory Aggressive B-cell LymphomasRefractory B-Cell Non-Hodgkin LymphomaAggressive B-cell NHL+10 more
Patrick C. Johnson, MD 28
Not applicableActive Not RecruitingNCT06024694
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma With CNS Involvement

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
IRCCS San Raffaele 45
Testing effectiveness (Phase 2)Study completedNCT01665768
What this trial is testing

Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma

Who this might be right for
CD20+, B-cell LymphomasMantle Cell LymphomaNon-Mantle Cell Low Grade B Cell Lymphomas (SLL/CLL)+3 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 56
Testing effectiveness (Phase 2)UnknownNCT06412068
What this trial is testing

A Prospective Study: Sintilimab and R-CHOP in PMBCL Treatment

Who this might be right for
Primary Mediastinal Large B Cell Lymphoma
Sun Yat-sen University 32
Testing effectiveness (Phase 2)Looking for participantsNCT07788118
What this trial is testing

A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7×19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma

Who this might be right for
Relapsed/Refractory Large B-cell Lymphoma (LBCL)Diffuse Large B-Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)+2 more
Second Affiliated Hospital, Zhejiang University, School of Medicine 70
Early research (Phase 1)Ended earlyNCT03893682
What this trial is testing

CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaNon-Hodgkin's Lymphoma
Aptose Biosciences Inc. 36
Early research (Phase 1)Looking for participantsNCT06544265
What this trial is testing

SynKIR-310 for Relapsed/Refractory B-NHL

Who this might be right for
B Cell LymphomaNHL, AdultMantle Cell Lymphoma+23 more
Verismo Therapeutics 36
Testing effectiveness (Phase 2)Ended earlyNCT03743246
What this trial is testing

Evaluate the Safety and Efficacy of JCAR017 in Pediatric Subjects With Relapsed/Refractory (r/r) B-cell Acute Lymphoblastic Leukemia (B-ALL) and B-cell Non-Hodgkin Lymphoma (B-NHL)

Who this might be right for
Precursor Cell Lymphoblastic Leukemia-LymphomaLymphoma, Non-Hodgkin
Celgene 21
Testing effectiveness (Phase 2)Looking for participantsNCT07249905
What this trial is testing

Dose Escalation and Dose Expansion Study of MDX2003 in Patients With Different Types of Lymphoma

Who this might be right for
LymphomaWaldenström Macroglobulinemia (WM)DLBCL - Diffuse Large B Cell Lymphoma+5 more
ModeX Therapeutics, An OPKO Health Company 180
Testing effectiveness (Phase 2)Looking for participantsNCT05934448
What this trial is testing

Pembro Plus CAR T-cell Therapy in R/R in PMBCL

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)Primary Mediastinal Large B Cell LymphomaPrimary Mediastinal Large B-Cell Lymphoma Refractory+3 more
Jennifer Crombie, MD 35
Not applicableLooking for participantsNCT05934084
What this trial is testing

Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors

Who this might be right for
Classical Hodgkin LymphomaDiffuse Large B Cell Lymphoma (DLBCL)Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 552
Testing effectiveness (Phase 2)Study completedNCT03610724
What this trial is testing

Phase II Open Label Trial to Determine Safety & Efficacy of Tisagenlecleucel in Pediatric Non-Hodgkin Lymphoma Patients

Who this might be right for
Non-Hodgkin Lymphoma
Novartis Pharmaceuticals 34
Not applicableNot Yet RecruitingNCT07463781
What this trial is testing

Neurocognitive Assessment in Adults Undergoing CD19 Targeted CAR-T Cell Therapy

Who this might be right for
Diffuse Large B Cell Lymphoma (DLBCL)High Grade B Cell LymphomaPrimary Mediastinal B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 100
Not applicableStudy completedNCT05162170
What this trial is testing

Primary Mediastinal Large B-cell Lymphoma (PMBCL): Multicenter Retrospective Study

Who this might be right for
Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Fondazione Italiana Linfomi - ETS 633
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