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Results for “PNH”

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Not applicableApproved For MarketingNCT00438789
What this trial is testing

The Paroxysmal Nocturnal Hemoglobinuria Early Access Treatment Protocol

Who this might be right for
Hemoglobinuria, Paroxysmal
Alexion Pharmaceuticals, Inc.
Testing effectiveness (Phase 2)Study completedNCT02598583
What this trial is testing

Dose-Escalation Study of ALXN1210 IV in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
PNH
Alexion Pharmaceuticals, Inc. 13
Early research (Phase 1)Looking for participantsNCT07152288
What this trial is testing

Investigation of Pharmacokinetics,Safety,and Pharmacodynamics of HSK39297 in Subjects With Hepatic Impairment

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Haisco Pharmaceutical Group Co., Ltd. 24
Not applicableStudy completedNCT05337683
What this trial is testing

A Retrospective Non-Interventional Study to Evaluate the Impact of Eculizumab in Korean PNH Patients

Who this might be right for
PNH
Handok Inc. 80
Not applicableEnded earlyNCT02179359
What this trial is testing

Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

Who this might be right for
Sickle Cell DiseaseTransfusion Dependent Alpha- or Beta- ThalassemiaDiamond Blackfan Anemia+5 more
Masonic Cancer Center, University of Minnesota 38
Large-scale testing (Phase 3)Active Not RecruitingNCT05133531
What this trial is testing

Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Regeneron Pharmaceuticals 202
Not applicableStudy completedNCT05274633
What this trial is testing

Real Life Use of Ravulizumab in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 120
Not applicableStudy completedNCT00039923
What this trial is testing

Transfer of GPI-Linked Proteins to Transfused Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Hemoglobinuria
National Heart, Lung, and Blood Institute (NHLBI) 7
Not applicableActive Not RecruitingNCT07413250
What this trial is testing

Assess Long-Term Safety of Danicopan Add-on Therapy in Participants With Paroxysmal Nocturnal Hemoglobinuria: Analysis of IPIG-Registry Data

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaPNH
Alexion Pharmaceuticals, Inc. 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06134414
What this trial is testing

Study of Safety and Efficacy of MY008211A in in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Wuhan Createrna Science and Technology Co., Ltd 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT06764303
What this trial is testing

NTQ5082 Capsules in the Treatment of Paroxysmal Nocturnal Hemoglobinuria Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Nanjing Chia-tai Tianqing Pharmaceutical 24
Testing effectiveness (Phase 2)Study completedNCT01529827
What this trial is testing

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in Remission+75 more
Roswell Park Cancer Institute 94
Large-scale testing (Phase 3)Looking for participantsNCT05795140
What this trial is testing

Evaluate Long-term Safety, Tolerability and Efficacy of Iptacopan in Study Participants With aHUS

Who this might be right for
Atypical Hemolytic Uremic Syndrome
Novartis Pharmaceuticals 65
Testing effectiveness (Phase 2)Looking for participantsNCT01174108
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

Who this might be right for
Severe Aplastic AnemiaMDS (Myelodysplastic Syndrome)
National Heart, Lung, and Blood Institute (NHLBI) 120
Large-scale testing (Phase 3)Study completedNCT07052838
What this trial is testing

Efficacy and Safety of HSK39297 in Anti-C5 Treated PNH Patients With Anemia

Who this might be right for
Paroxysmal Nocturnal Haemoglobinuria (PNH)
Haisco Pharmaceutical Group Co., Ltd. 36
Large-scale testing (Phase 3)Study completedNCT03500549
What this trial is testing

Study to Evaluate the Efficacy and Safety of APL-2 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Apellis Pharmaceuticals, Inc. 80
Testing effectiveness (Phase 2)Study completedNCT05972967
What this trial is testing

Safety and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria Patients With a Sub-optimal Response to Ravulizumab

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Omeros Corporation 12
Testing effectiveness (Phase 2)Study completedNCT01194804
What this trial is testing

E07-001: Safety and Efficacy Extension Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 27
Early research (Phase 1)Study completedNCT06294301
What this trial is testing

Single and Multiple Doses of LP-005 in Healthy Adult Participants

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Longbio Pharma 68
Early research (Phase 1)Study completedNCT02264639
What this trial is testing

A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Apellis Pharmaceuticals, Inc. 9
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