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Results for “PNH - Paroxysmal Nocturnal Hemoglobinuria”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT06799546
What this trial is testing

A Phase III Study to Evaluate the Efficacy and Safety of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria Who Are Naive to Complement Inhibitor Therapy

Who this might be right for
PNH
Haisco Pharmaceutical Group Co., Ltd. 73
Not applicableStudy completedNCT05842486
What this trial is testing

Hematological Response in Patients With Paroxysmal Nocturnal Hemoglobinuria Treated With Anti-C5 Antibody: an External Control Arm Study for Iptacopan Use in Anti-C5 naïve Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Assistance Publique - Hôpitaux de Paris 92
Not applicableActive Not RecruitingNCT06606314
What this trial is testing

Specified Drug-use Surveillance of Fabhalta Capsules

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals 132
Large-scale testing (Phase 3)Study completedNCT05886244
What this trial is testing

Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) in China

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 25
Testing effectiveness (Phase 2)Study completedNCT00731328
What this trial is testing

Donor Stem Cell Transplant After Busulfan, Fludarabine, Methylprednisolone, and Antithymocyte Globulin in Treating Patients With Bone Marrow Failure Syndrome

Who this might be right for
LeukemiaMyelodysplastic SyndromesNonmalignant Neoplasm+1 more
Asan Medical Center 15
Testing effectiveness (Phase 2)Looking for participantsNCT07187401
What this trial is testing

A First-in-Human Safety and Efficacy Study of ALN-CFB, a Small Interfering RNA (siRNA) Targeting Complement Factor B, in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria With Persistent Anemia on a C5 Inhibitor

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)Persistent Anemia
Regeneron Pharmaceuticals 24
Large-scale testing (Phase 3)Not Yet RecruitingNCT07747090
What this trial is testing

The Efficacy and Safety of FXS6837 Capsules Compared to Eculizumab for 24 Weeks in Patients With PNH.

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 90
Testing effectiveness (Phase 2)Study completedNCT03181633
What this trial is testing

A Long-Term Treatment Study of ACH-0144471 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 8
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06134414
What this trial is testing

Study of Safety and Efficacy of MY008211A in in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Wuhan Createrna Science and Technology Co., Ltd 40
Not applicableEnded earlyNCT07036718
What this trial is testing

NIS PDC the Efficacy and Safety of Iptacopan in Adults in Routine Clinical Practice

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals 6
Testing effectiveness (Phase 2)Looking for participantsNCT06412497
What this trial is testing

MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.

Who this might be right for
Severe Aplastic AnemiaAcquired Amegakaryocytic ThrombocytopeniaAcquired Pure Red Cell Aplasia+1 more
Masonic Cancer Center, University of Minnesota 60
Testing effectiveness (Phase 2)Study completedNCT01194804
What this trial is testing

E07-001: Safety and Efficacy Extension Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 27
Large-scale testing (Phase 3)Study completedNCT04060264
What this trial is testing

Clinical Trial of BCD-148 and Soliris® for the Treatment of Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Biocad 28
Large-scale testing (Phase 3)Study completedNCT07052838
What this trial is testing

Efficacy and Safety of HSK39297 in Anti-C5 Treated PNH Patients With Anemia

Who this might be right for
Paroxysmal Nocturnal Haemoglobinuria (PNH)
Haisco Pharmaceutical Group Co., Ltd. 36
Not applicableStudy completedNCT04079257
What this trial is testing

The Pharmacokinetics and Pharmacodynamics of Eculizumab in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaEculizumabPK-PD
Radboud University Medical Center 27
Testing effectiveness (Phase 2)Study completedNCT05972967
What this trial is testing

Safety and Efficacy of OMS906 in Paroxysmal Nocturnal Hemoglobinuria Patients With a Sub-optimal Response to Ravulizumab

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Omeros Corporation 12
Testing effectiveness (Phase 2)Looking for participantsNCT06745622
What this trial is testing

Long-term Safety and Tolerability of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Haisco Pharmaceutical Group Co., Ltd. 47
Testing effectiveness (Phase 2)Looking for participantsNCT05876312
What this trial is testing

Safety, Tolerability, PK and PD of ADX-038 in Healthy Participants and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
ADARx Pharmaceuticals, Inc. 50
Early research (Phase 1)Looking for participantsNCT07256301
What this trial is testing

A Phase Ib, Multicenter, Open-Label Study of Multiple-Dose EA5 in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
PNH - Paroxysmal Nocturnal Hemoglobinuria
Shanghai Lanyi Therapeutics Co., Ltd. 24
Not applicableLooking for participantsNCT07457151
What this trial is testing

Danicopan PMS in Korea

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
AstraZeneca 27
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