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Results for “PNH - Paroxysmal Nocturnal Hemoglobinuria”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06764303
What this trial is testing

NTQ5082 Capsules in the Treatment of Paroxysmal Nocturnal Hemoglobinuria Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Nanjing Chia-tai Tianqing Pharmaceutical 24
Not applicableActive Not RecruitingNCT03047746
What this trial is testing

Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF

Who this might be right for
Acquired Aplastic AnemiaParoxysmal Nocturnal HemoglobinuriaInherited Bone Marrow Failure Syndromes
Children's Hospital of Philadelphia 50
Testing effectiveness (Phase 2)Study completedNCT00975975
What this trial is testing

Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer

Who this might be right for
Acute Myelogenous LeukemiaAcute Lymphocytic LeukemiaChronic Myelogenous Leukemia+8 more
Indiana University 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05646524
What this trial is testing

Study of Efficacy and Safety of NM8074 in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
NovelMed Therapeutics 12
Early research (Phase 1)Study completedNCT05642585
What this trial is testing

Single-dose MY008211A in Healthy Adults

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Wuhan Createrna Science and Technology Co., Ltd 63
Large-scale testing (Phase 3)Study completedNCT00122317
What this trial is testing

Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Hemoglobinuria, Nocturnal
Alexion Pharmaceuticals, Inc. 187
Not applicableEnrolling By InvitationNCT07102849
What this trial is testing

Molecular and Clinical Analysis of Bone Marrow Failure: A Secondary Research Study

Who this might be right for
Bone Marrow Failure DisordersVEXAS SyndromeHemoglobinurea, Paroxysmal+2 more
National Heart, Lung, and Blood Institute (NHLBI) 1,400
Testing effectiveness (Phase 2)Ended earlyNCT04170023
What this trial is testing

Study of the Oral Factor D (FD) Inhibitor ALXN2050 in PNH Patients as Monotherapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Alexion Pharmaceuticals, Inc. 29
Testing effectiveness (Phase 2)Ended earlyNCT05116774
What this trial is testing

BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
BioCryst Pharmaceuticals 12
Testing effectiveness (Phase 2)Study completedNCT06051357
What this trial is testing

Proof of Concept Study to Assess the Efficacy, Safety of HRS-5965 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Chengdu Suncadia Medicine Co., Ltd. 26
Testing effectiveness (Phase 2)Looking for participantsNCT03520647
What this trial is testing

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

Who this might be right for
Severe Aplastic Anemia (SAA)Hypo-Plastic Myelodysplastic Syndrome (MDS)Paroxysmal Nocturnal Hemoglobinuria (PNH)
National Heart, Lung, and Blood Institute (NHLBI) 56
Not applicableStudy completedNCT01192425
What this trial is testing

Paroxysmal Nocturnal Hemoglobinuria (PNH), Level of CD59 on Red and White Blood Cells in Bone Marrow Failure Syndromes

Who this might be right for
Hemoglobinuria
Alexion Pharmaceuticals, Inc. 5,580
Post-approval studies (Phase 4)Study completedNCT00867932
What this trial is testing

Eculizumab Pharmacokinetics/Pharmacodynamics Study in Pediatric/Adolescent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Hemoglobinuria, Paroxysmal
Alexion Pharmaceuticals, Inc. 7
Testing effectiveness (Phase 2)Study completedNCT04811716
What this trial is testing

Pozelimab and Cemdisiran Combination Treatment in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Who Have Received Pozelimab Monotherapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Regeneron Pharmaceuticals 24
Not applicableStudy completedNCT00039923
What this trial is testing

Transfer of GPI-Linked Proteins to Transfused Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Hemoglobinuria
National Heart, Lung, and Blood Institute (NHLBI) 7
Large-scale testing (Phase 3)Looking for participantsNCT06934967
What this trial is testing

Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Novartis Pharmaceuticals 12
Testing effectiveness (Phase 2)Study completedNCT04330534
What this trial is testing

First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
BioCryst Pharmaceuticals 168
Large-scale testing (Phase 3)Looking for participantsNCT05744921
What this trial is testing

A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Regeneron Pharmaceuticals 202
Large-scale testing (Phase 3)Ended earlyNCT04162470
What this trial is testing

REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate Its Long Term Safety, Efficacy and Tolerability.

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Regeneron Pharmaceuticals 24
Large-scale testing (Phase 3)Looking for participantsNCT06932744
What this trial is testing

Study of Safety and Efficacy of MY008211A in Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Who Are Naive to Complement Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Haemoglobinuria (PNH)
Wuhan Createrna Science and Technology Co., Ltd 66
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