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Results for “POLE/POLD1 Mutation Tumor”

6 trials

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Showing 6 of 6 results

Not applicableLooking for participantsNCT05420064
What this trial is testing

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Who this might be right for
BRCA1 MutationPOLD1 Gene MutationCDKN2A Mutation+19 more
Memorial Sloan Kettering Cancer Center 1,000
Not applicableLooking for participantsNCT05103969
What this trial is testing

Cohort of Tumors With POLE/D1 Mutation

Who this might be right for
TumorsPOLE Exonuclease Domain MutationPOLD1 Gene Mutation
Federation Francophone de Cancerologie Digestive 100
Testing effectiveness (Phase 2)UnknownNCT03810339
What this trial is testing

Toripalimab as Monotherapy in Participants With POLE or POLD-1 Mutated and Non-MSI-H Advanced Solid Tumors

Who this might be right for
Solid TumorAdvanced Cancer
Sun Yat-sen University 35
Testing effectiveness (Phase 2)Looking for participantsNCT03428802
What this trial is testing

Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene MutationLocally Advanced Solid Neoplasm+17 more
Rutgers, The State University of New Jersey 40
Testing effectiveness (Phase 2)UnknownNCT03491345
What this trial is testing

K-Basket, Avelumab, Biomarker-driven, Advanced Solid Tumor

Who this might be right for
PD-L1 Positive Mutation TumorEBV Positive Mutation TumorMSI-H Mutation Tumor+1 more
Yonsei University 60
Testing effectiveness (Phase 2)UnknownNCT04969029
What this trial is testing

Immunotherapy Versus Chemotherapy as Adjuvant Therapy for Colon Cancer With MSI-H or POLE/ POLD1 Mutations

Who this might be right for
ImmunotherapyAdjuvant TherapyColon Cancer+1 more
Tianjin Medical University Cancer Institute and Hospital 30