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Results for “POMC Deficiency Obesity”

8 trials

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Showing 8 of 8 results

Large-scale testing (Phase 3)Study completedNCT05194124
What this trial is testing

Phase 3 Crossover Trial of Two Formulations of Setmelanotide in Participants With Specific Gene Defects in the MC4R Pathway

Who this might be right for
Bardet-Biedl SyndromePOMC Deficiency
Rhythm Pharmaceuticals, Inc. 19
Not applicableActive Not RecruitingNCT06239064
What this trial is testing

Early Genetic Identification of Obesity

Who this might be right for
Obesity, ChildhoodHyperphagiaRetinopathy+5 more
Rolfs Consulting und Verwaltungs-GmbH (RCV) 1,000
Testing effectiveness (Phase 2)Study completedNCT03013543
What this trial is testing

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

Who this might be right for
Genetic ObesityObesityObesity Due to Melanocortin 4 Receptor Deficiency
Rhythm Pharmaceuticals, Inc. 213
Large-scale testing (Phase 3)Study completedNCT04966741
What this trial is testing

Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity

Who this might be right for
Bardet-Biedl SyndromePOMC Deficiency ObesityPCSK1 Deficiency Obesity+1 more
Rhythm Pharmaceuticals, Inc. 12
Large-scale testing (Phase 3)Study completedNCT02896192
What this trial is testing

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

Who this might be right for
Pro-opiomelanocortin (POMC) Deficiency Obesity
Rhythm Pharmaceuticals, Inc. 15
Not applicableStudy completedNCT03621007
What this trial is testing

An Observational,Prospective Natural History Study of Early-Onset Extreme Obesity Due to Bi-Allelic Loss-of-Function Mutations in the POMC, PCSK1 or LEPR Genes

Who this might be right for
POMC Deficiency ObesityPCSK1 Deficiency ObesityLEPR Deficiency Obesity
Rhythm Pharmaceuticals, Inc. 8
Not applicableActive Not RecruitingNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Testing effectiveness (Phase 2)UnknownNCT06041841
What this trial is testing

Assess Efficacy and Safety of LB54640 in Patients With Genetic Obesity

Who this might be right for
POMC Deficiency ObesityPCSK1 Deficiency ObesityLEPR Deficiency Obesity
LG Chem 4