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Results for “PRAME Positive”

10 trials

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Showing 10 of 10 results

Early research (Phase 1)Looking for participantsNCT07156136
What this trial is testing

Study of IMC-P115C in Advanced PRAME-Positive Cancers

Who this might be right for
PRAME PositiveCancerHLA-A*02:01-positive
Immunocore Ltd 140
Not applicableTemporarily pausedNCT07258446
What this trial is testing

PRAME Immunohistochemistry-Guided Slow Mohs Micrographic Surgery for the Treatment of Stage 0 to IIc Cutaneous Melanoma

Who this might be right for
Clinical Stage 0 Cutaneous Melanoma AJCC v8Clinical Stage I Cutaneous Melanoma AJCC v8Clinical Stage II Cutaneous Melanoma AJCC v8
University of California, Davis 36
Testing effectiveness (Phase 2)Study completedNCT03318900
What this trial is testing

T-Cell Infusion, Aldesleukin, and Utomilumab in Treating Patients With Recurrent Ovarian Cancer

Who this might be right for
COL6A3 PositiveHLA-A*0201 Positive Cells PresentPRAME Positive+1 more
M.D. Anderson Cancer Center 5
Not applicableActive Not RecruitingNCT05812027
What this trial is testing

A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerCervical CancerNon Small Cell Lung Cancer+4 more
TScan Therapeutics, Inc. 1,150
Early research (Phase 1)Not Yet RecruitingNCT07664735
What this trial is testing

Evaluate the Safety and Efficacy of OPB-201 in Recurrent Endometrial and Platinum-resistant Ovarian Cancer.

Who this might be right for
Endometrial Cancer RecurrentEndometrial CancerAdvanced Endometrial Cancer+4 more
Outpace Bio, Inc. 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04262466
What this trial is testing

Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors

Who this might be right for
Select Advanced Solid Tumors
Immunocore Ltd 410
Testing effectiveness (Phase 2)Study completedNCT01853878
What this trial is testing

Demonstrate the Benefit of a New Kind of Anti-cancer Treatment [PReferentially Expressed Antigen of MElanoma (PRAME) Immunotherapy] for Patients With Non-Small Cell Lung Cancer (NSCLC), After Removal of Their Tumor

Who this might be right for
Lung Cancer, Non-Small Cell
GlaxoSmithKline 137
Early research (Phase 1)Active Not RecruitingNCT05973487
What this trial is testing

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Who this might be right for
Head and Neck CancerCervical CancerNon-small Cell Carcinoma+18 more
TScan Therapeutics, Inc. 840
Early research (Phase 1)Not Yet RecruitingNCT07796061
What this trial is testing

Blood-Brain Barrier Disruption Using Exablate Magnetic Resonance-Guided Low Intensity Focused Ultrasound With Microbubbles in Combination With T-Cell Infusion in Patients With Newly Diagnosed Diffuse Midline Glioma (LIFT)

Who this might be right for
Pontine Diffuse Midline GliomaDiffuse Intrinsic Pontine GliomaThalamic Diffuse Midline Glioma
Children's National Research Institute 45
Early research (Phase 1)Ended earlyNCT01159964
What this trial is testing

Evaluation of a New Anti-cancer Vaccine for Patients With Non-small Cell Lung Cancer, After Tumor Removal by Surgery

Who this might be right for
Lung Cancer, Non-Small Cell
GlaxoSmithKline 60