Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “PTEN”

98 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 98 results

Not applicableStudy completedNCT01451983
What this trial is testing

Genetics, Brain Structure and Thinking Skills in Autism

Who this might be right for
Autism Spectrum Disorders
The Cleveland Clinic 138
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05540275
What this trial is testing

Tislelizumab (One Anti-PD-1 Antibody) Plus Low-dose Bevacizumab for Bevacizumab Refractory Recurrent Glioblastoma

Who this might be right for
Recurrent Glioblastoma
Henan Provincial People's Hospital 30
Not applicableLooking for participantsNCT07297134
What this trial is testing

PTEN and Organ-Specific microRNAs in Metastatic Breast Cancer

Who this might be right for
Breast CancerMetastatic Breast CancermiRNAs+1 more
Atlas University 160
Early research (Phase 1)Ended earlyNCT04770246
What this trial is testing

TAS-117 in Patients With Advanced Solid Tumors Harboring Germline PTEN Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors Irrespective of Gene AlterationsAdvanced or Metastatic Solid Tumors With Germline PTEN Inactivating Mutations
Taiho Oncology, Inc. 17
Early research (Phase 1)Study completedNCT01430572
What this trial is testing

Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients

Who this might be right for
Advanced CancersSolid Tumors
M.D. Anderson Cancer Center 62
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439175
What this trial is testing

Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Study completedNCT00975819
What this trial is testing

Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies

Who this might be right for
Kaposiform HemangioendotheliomasTufted AngiomaCapillary Venous Lymphatic Malformation+6 more
Denise Martin Adams 61
Not applicableStudy completedNCT03680924
What this trial is testing

Access to Resources for Patients With PTEN Hamartoma Tumor Syndrome

Who this might be right for
PTEN Gene Mutation
University of South Florida 13
Not applicableLooking for participantsNCT02573636
What this trial is testing

The Predictive Value of Coexisting TMPRSS2-ERG Gene Fusion and PTEN Deletion in Prostate Cancer Patients with Biochemical Failure Status Post Salvage or Radical Radiation Therapy

Who this might be right for
Prostate Cancer
Sir Mortimer B. Davis - Jewish General Hospital 208
Not applicableLooking for participantsNCT05420064
What this trial is testing

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Who this might be right for
BRCA1 MutationPOLD1 Gene MutationCDKN2A Mutation+19 more
Memorial Sloan Kettering Cancer Center 1,000
Not applicableStudy completedNCT04873206
What this trial is testing

Diagnostic and Prognostic Value of PTEN Expression in Functional and Pathological Endometrial Biopsies

Who this might be right for
Endometrial HyperplasiaEndometrial Adenocarcinoma
Sohag University 80
Testing effectiveness (Phase 2)Study completedNCT04740190
What this trial is testing

Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd

Who this might be right for
Recurrent GliomaRecurrent GlioblastomaPoly ADP Ribose Polymerase (PARP) Inhibitor+2 more
The University of Hong Kong 33
Not applicableUnknownNCT03971318
What this trial is testing

A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With LBL

Who this might be right for
Lymphoma, Non-HodgkinLymphoblastic Lymphoma, ChildhoodPTEN Loss+2 more
Sun Yat-sen University 300
Not applicableStudy completedNCT02724501
What this trial is testing

Studies of the Tumour Suppressor Gene PTEN - Endometrial Cancer

Who this might be right for
Endometrial Neoplasms
University Health Network, Toronto 217
Not applicableWithdrawnNCT00173407
What this trial is testing

PTEN and IGFBP-3 Correlation in Ovarian Carcinoma Invasion

Who this might be right for
Ovarian Cancer
National Taiwan University Hospital
Early research (Phase 1)Ended earlyNCT04586270
What this trial is testing

TAS0612 in Participants With Advanced or Metastatic Solid Tumor Cancer

Who this might be right for
Advanced or Metastatic Solid Tumors
Taiho Oncology, Inc. 47
Not applicableUnknownNCT01987518
What this trial is testing

French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis

Who this might be right for
Quality of Life
Hôpital Edouard Herriot 350
Testing effectiveness (Phase 2)Study completedNCT00317720
What this trial is testing

Trastuzumab and RAD001 in Patients With Human Epidermal Growth Receptor 2 (HER-2) Overexpressing Breast Cancer

Who this might be right for
Breast CancerNeoplasm Metastasis
M.D. Anderson Cancer Center 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT04439149
What this trial is testing

Testing GSK2636771 as a Potential Targeted Treatment in Cancers With PTEN Genetic Changes (MATCH-Subprotocol N)

Who this might be right for
Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Looking for participantsNCT06029998
What this trial is testing

Bortezomib in Patients With Metastatic Castration-Resistant Prostate Cancer With PTEN Deletion

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
University of Utah 22
Load More Results