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Results for “PTEN Gene Mutation”

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Showing 14 of 0 results

Not applicableTemporarily pausedNCT05630105
What this trial is testing

Cancer Risk Assessment in Patients With a Constitutional Alteration of the PTEN Gene

Who this might be right for
PTEN Gene Mutation
Institut Bergonié 430
Testing effectiveness (Phase 2)Ended earlyNCT04108858
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8HER2-Positive Breast CarcinomaMetastatic Breast Carcinoma
National Cancer Institute (NCI) 2
Large-scale testing (Phase 3)Ended earlyNCT04251533
What this trial is testing

Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss

Who this might be right for
Triple Negative Breast Neoplasms
Novartis Pharmaceuticals 137
Testing effectiveness (Phase 2)Active Not RecruitingNCT04042831
What this trial is testing

Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations

Who this might be right for
Bile Duct AdenocarcinomaFanconi Anemia Complementation Group Gene MutationMetastatic Bile Duct Carcinoma+1 more
Academic and Community Cancer Research United 32
Early research (Phase 1)Study completedNCT03317119
What this trial is testing

Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery

Who this might be right for
Metastatic Colon CarcinomaMetastatic Colorectal CarcinomaMetastatic Rectal Carcinoma+22 more
City of Hope Medical Center 26
Not applicableUnknownNCT03971318
What this trial is testing

A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With LBL

Who this might be right for
Lymphoma, Non-HodgkinLymphoblastic Lymphoma, ChildhoodPTEN Loss+2 more
Sun Yat-sen University 300
Testing effectiveness (Phase 2)UnknownNCT03273595
What this trial is testing

Lapatinib Plus Chemotherapy Versus Trastuzumab Plus Chemotherapy in HER2-positive Breast Cancer

Who this might be right for
Neoplasms, Breast
Xijing Hospital 100
Not applicableStudy completedNCT03680924
What this trial is testing

Access to Resources for Patients With PTEN Hamartoma Tumor Syndrome

Who this might be right for
PTEN Gene Mutation
University of South Florida 13
Testing effectiveness (Phase 2)Ended earlyNCT02822482
What this trial is testing

Copanlisib in Association With Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinomas Harboring a PI3KCA Mutation/Amplification and/or a PTEN Loss

Who this might be right for
Carcinoma, Squamous Cell of Head and Neck
UNICANCER 11
Not applicableUnknownNCT01987518
What this trial is testing

French Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic Polyposis

Who this might be right for
Quality of Life
Hôpital Edouard Herriot 350
Early research (Phase 1)Looking for participantsNCT06944457
What this trial is testing

Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of MPD-1 in Patients With Advanced Solid Tumor

Who this might be right for
CancerSolid Tumor CancerBiomarkers
Pharosgen Co.,Ltd 24
Testing effectiveness (Phase 2)Study completedNCT01802320
What this trial is testing

Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery

Who this might be right for
Colon Mucinous AdenocarcinomaColon Signet Ring Cell AdenocarcinomaRectal Mucinous Adenocarcinoma+13 more
National Cancer Institute (NCI) 18
Testing effectiveness (Phase 2)Study completedNCT02991807
What this trial is testing

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

Who this might be right for
PTEN Gene MutationPTEN Hamartoma Tumor Syndrome
Boston Children's Hospital 46
Early research (Phase 1)Ended earlyNCT05300048
What this trial is testing

Combination of Serabelisib and Insulin Suppressing Diet With or Without Nab-paclitaxel in Subjects With Advanced Solid Tumors With PIK3CA Mutations

Who this might be right for
Advanced Solid TumorPIK3CA MutationPTEN Loss of Function Mutation
Faeth Therapeutics 34