Not applicableStudy completedNCT03680924What this trial is testingAccess to Resources for Patients With PTEN Hamartoma Tumor SyndromeWho this might be right forPTEN Gene Mutation University of South Florida 13
Not applicableUnknownNCT01987518What this trial is testingFrench Digestive Polyposis Cohorte Family Adenomatous Polyposis With APC and MYH Gene Mutations , Cowden's Disease With PTEN Gene Mutation, Peutz Jeghers Disease With STK 11 Gene Mutation ,juvénil Polyposis With SMAD 4 Gene Mutation , Serrated and Hyperplastic PolyposisWho this might be right forQuality of Life Hôpital Edouard Herriot 350
Not applicableLooking for participantsNCT06805734What this trial is testingNatural History With Focus on Oncological Risk Evaluation in Pediatric Patients With PTEN Pathogenic VariantsWho this might be right forPTEN Hamartoma Syndrome Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 50
Not applicableUnknownNCT03630523What this trial is testingResponse of Immune System to Flu Vaccination in PHTSWho this might be right forPTEN Hamartoma Tumor Syndrome Radboud University Medical Center 30
Not applicableLooking for participantsNCT06888388What this trial is testingLong-term Safety of Nipple Sparing Mastectomy in Women With High Penetrance Breast Cancer Susceptibility Genes in Breast CancerWho this might be right forBreast Cancer Surgery Sir Mortimer B. Davis - Jewish General Hospital 4,700
Testing effectiveness (Phase 2)Study completedNCT00971789What this trial is testingSirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor SyndromesWho this might be right forCowden's DiseaseHamartoma Syndrome, Multiple National Cancer Institute (NCI) 18
Testing effectiveness (Phase 2)Study completedNCT04094675What this trial is testingSirolimus for Cowden Syndrome With Colon PolyposisWho this might be right forPTEN Gene MutationPTEN Hamartoma Tumor SyndromePTEN Hamartoma Syndrome+4 more Ohio State University 5
Not applicableStudy completedNCT00040222What this trial is testingClinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian CancerWho this might be right forFamilial Ovarian CancerFamilial Breast CancerBRCA1-associate Malignancies+1 more National Cancer Institute (NCI) 377
Not applicableUnknownNCT06163365What this trial is testingInherited Cancer Early Diagnosis (ICED) StudyWho this might be right forLi Fraumeni SyndromeLynch SyndromeHereditary Diffuse Gastric Cancer+5 more Royal Marsden NHS Foundation Trust 100
Testing effectiveness (Phase 2)Study completedNCT02991807What this trial is testingRAD001 and Neurocognition in PTEN Hamartoma Tumor SyndromeWho this might be right forPTEN Gene MutationPTEN Hamartoma Tumor Syndrome Boston Children's Hospital 46
Not applicableLooking for participantsNCT03702309What this trial is testingLiquid Biopsy Evaluation and Repository Development at Princess MargaretWho this might be right forCancerBreast CancerLung Cancer+15 more University Health Network, Toronto 2,500
Not applicableLooking for participantsNCT06523582What this trial is testingGenetic Bases of Neuroendocrine Neoplasms in Mexican PatientsWho this might be right forNeuroendocrine NeoplasmNeuroendocrine Neoplasm of Gastrointestinal TractNeuroendocrine Neoplasm of Lung+23 more Universidad Nacional Autonoma de Mexico 750
Testing effectiveness (Phase 2)Study completedNCT00600275What this trial is testingA Phase I/II Study of BGT226 in Adult Patients With Advanced Solid Malignancies Including Patients With Advanced Breast CancerWho this might be right forSolid TumorsBreast CancerCowden Syndrome Novartis Pharmaceuticals 57
Early research (Phase 1)Study completedNCT00620594What this trial is testingA Phase I/II Study of BEZ235 in Patients With Advanced Solid Malignancies Enriched by Patients With Advanced Breast CancerWho this might be right forBreast CancerAdvanced Solid TumorsCowden Syndrome Novartis Pharmaceuticals 183
Not applicableStudy completedNCT05671107What this trial is testingDevelopment and Validation of an Online Neurobehavioral Evaluation Tool for PTEN PatientsWho this might be right forPTEN Hamartoma Tumor Syndrome John Carroll University 300
Not applicableLooking for participantsNCT06712095What this trial is testingVideo Capsule Examination in Patients With Lynch SyndromeWho this might be right forLynch SyndromeLi Fraumeni SyndromePTEN Hamartoma Syndrome+7 more Royal Marsden NHS Foundation Trust 25
Not applicableLooking for participantsNCT02461446What this trial is testingNatural History Study of Individuals With Autism and Germline Heterozygous PTEN MutationsWho this might be right forPTENASDAutism+2 more Boston Children's Hospital 170
Not applicableLooking for participantsNCT03050268What this trial is testingFamilial Investigations of Childhood Cancer PredispositionWho this might be right forAcute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more St. Jude Children's Research Hospital 1,500
Large-scale testing (Phase 3)Not Yet RecruitingNCT07218575What this trial is testingDouble-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline MutationsWho this might be right forCowden's DiseaseCowden's SyndromeLhermitte-Duclos Disease+6 more Boston Children's Hospital 60
Not applicableLooking for participantsNCT06462430What this trial is testingPTEN Hamartoma Tumor Syndrome Pediatric Patient RegistryWho this might be right forPTEN Hamartoma Tumor SyndromeMacrocephaly Autism Syndrome Yale University 100