Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “PTSD and Substance Use Disorder”

180 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 180 results

Not applicableStudy completedNCT01274741
What this trial is testing

Present- Versus Past-focused Therapy for PTSD and Substance Use Disorder

Who this might be right for
Posttraumatic Stress DisorderSubstance Use DisorderAlcohol Use Disorder
VA Boston Healthcare System 52
Early research (Phase 1)Study completedNCT04827056
What this trial is testing

Effect of Sublingual Formulation of Dexmedetomidine HCl (BXCL501) - Alcohol Interaction Study

Who this might be right for
Alcohol Use Disorder (AUD)Post Traumatic Stress Disorder (PTSD)
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance 10
Post-approval studies (Phase 4)Study completedNCT02504931
What this trial is testing

Serotonin Selective Reuptake Inhibitor Treatment of Dual Diagnosis Post-traumatic Stress Disorder and Alcohol Problems

Who this might be right for
PTSDAlcohol Use Disorder
The University of Texas Health Science Center at San Antonio 49
Early research (Phase 1)Study completedNCT00946322
What this trial is testing

Couple-Based Treatment for Alcohol Use Disorders and Post-Traumatic Stress Disorder

Who this might be right for
Alcohol-related DisordersPost-traumatic Stress Disorder
VA Office of Research and Development 13
Not applicableEnded earlyNCT01408641
What this trial is testing

Topiramate for Alcohol Use in Posttraumatic Stress Disorder

Who this might be right for
Alcohol DependenceAlcoholismAlcohol Abuse+3 more
University of Maryland, Baltimore 4
Not applicableStudy completedNCT02461732
What this trial is testing

Trial of a Novel Cognitive-Behavioral Treatment for Posttraumatic Stress and Substance Dependence

Who this might be right for
Posttraumatic Stress DisorderSubstance Dependence
The University of Texas Health Science Center, Houston 60
Not applicableLooking for participantsNCT06367764
What this trial is testing

A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations

Who this might be right for
PTSD
Stanford University 400
Testing effectiveness (Phase 2)Study completedNCT04360681
What this trial is testing

Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans

Who this might be right for
Post Traumatic Stress DisorderOpioid-use Disorder
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance 84
Not applicableNot Yet RecruitingNCT07397507
What this trial is testing

Mechanisms of Written Exposure Therapy in Residential SUD Treatment

Who this might be right for
PTSD - Post Traumatic Stress DisorderSubstance Use Disorder (SUD)
Mclean Hospital 108
Large-scale testing (Phase 3)Study completedNCT03176953
What this trial is testing

Topiramate and Prolonged Exposure

Who this might be right for
PTSD and Alcohol Use Disorder
VA Office of Research and Development 100
Not applicableEnrolling By InvitationNCT05821634
What this trial is testing

Personalizing Treatment Delivery

Who this might be right for
Anxiety Disorders and SymptomsPTSD and Trauma-related SymptomsAlcohol; Use, Problem; Alcohol Use Disorder
Rutgers, The State University of New Jersey 81
Not applicableLooking for participantsNCT05327504
What this trial is testing

Written Exposure Therapy for Veterans With SUD and PTSD

Who this might be right for
Substance Use DisordersPosttraumatic Stress Disorder
VA Office of Research and Development 170
Testing effectiveness (Phase 2)Ended earlyNCT03852628
What this trial is testing

Kappa Opioid Receptor Antagonism for the Tx of AUD and Comorbid PTSD

Who this might be right for
Post Traumatic Stress DisorderAlcohol Abuse
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance 69
Not applicableLooking for participantsNCT06968832
What this trial is testing

Project COMET: Massed Prolonged Exposure for PTSD and SUD

Who this might be right for
Posttraumatic Stress Disorder (PTSD)Substance Use Disorders (SUD)Comorbidity+1 more
Rutgers, The State University of New Jersey 168
Testing effectiveness (Phase 2)UnknownNCT05692271
What this trial is testing

Testing a Novel Therapeutic Strategy for Comorbid Post-Traumatic Stress Disorder and Alcohol Use Disorder

Who this might be right for
Stress Disorders, Post-TraumaticAlcohol Use Disorder
Centre for Addiction and Mental Health 48
Not applicableStudy completedNCT04163341
What this trial is testing

Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States

Who this might be right for
HIV/AIDSDepressionAnxiety+2 more
Michael J Mugavero, MD 60
Not applicableStudy completedNCT04559893
What this trial is testing

Collaboration Leading to Addiction Treatment and Recovery From Other Stresses

Who this might be right for
Opioid-use DisorderAddictionDepression+1 more
RAND 729
Not applicableEnrolling By InvitationNCT04356274
What this trial is testing

Local Participatory Systems Dynamics to Increase Reach of Evidence Based Addiction and Mental Health Care

Who this might be right for
PTSDDepressionAlcohol Use Disorder+1 more
Palo Alto Veterans Institute for Research 720
Early research (Phase 1)WithdrawnNCT04464148
What this trial is testing

Feasibility Trial of Pregnenolone for Posttraumatic Stress Disorder and Alcohol Use Disorder

Who this might be right for
Post Traumatic Stress DisorderAlcohol Use Disorder
University of Texas Southwestern Medical Center
Not applicableLooking for participantsNCT06804525
What this trial is testing

LHC-CIDI-5 in Hong Kong

Who this might be right for
Major Depressive Episode (MDE)Major Depressive Disorder (MDD)Persistent Depressive Disorder (PDD)+20 more
The University of Hong Kong 2,500
Load More Results