Not applicableLooking for participantsNCT02321423What this trial is testingInternational Pachyonychia Congenita Research RegistryWho this might be right forPachyonychia Congenita Pachyonychia Congenita Project 2,000
Early research (Phase 1)Study completedNCT02592954What this trial is testingEffect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal SkinWho this might be right forEpidermolysis Bullosa SimplexPachyonychia Congenita Johns Hopkins University 5
Early research (Phase 1)Study completedNCT00716014What this trial is testingStudy of TD101, a Small Interfering RNA (siRNA) Designed for Treatment of Pachyonychia CongenitaWho this might be right forPachyonychia Congenita Pachyonychia Congenita Project 1
Early research (Phase 1)Study completedNCT05435638What this trial is testingStudy Designed to Evaluate Safety and Efficacy of 1% Topical Formulation of KM-001 on Type 1 Punctate Palmoplantar Keratoderma or Pachyonychia Congenita DiseasesWho this might be right forPunctate Palmoplantar Keratoderma Type 1Pachyonychia Congenita Orvida Pharma (formerly Kamari Pharma) 14
Testing effectiveness (Phase 2)UnknownNCT00936533What this trial is testingBotulinumtoxin A Treatment in Epidermolysis Bullosa Simplex and Pachyonychia CongenitaWho this might be right forEpidermolysis Bullosa Simplex Uppsala University 40
Large-scale testing (Phase 3)Study completedNCT04520750What this trial is testingVALO-2: Study Evaluating the Safety and Efficacy of PTX022 in the Treatment of Adults With Pachyonychia CongenitaWho this might be right forPachyonychia Congenita Palvella Therapeutics, Inc. 36
Large-scale testing (Phase 3)Study completedNCT05180708What this trial is testingA Multicenter, Phase 3 Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Pachyonychia CongenitaWho this might be right forPachyonychia Congenita Palvella Therapeutics, Inc. 87
Large-scale testing (Phase 3)Looking for participantsNCT05643872What this trial is testingA Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia CongenitaWho this might be right forPachyonychia Congenita Palvella Therapeutics, Inc. 45
Early research (Phase 1)Study completedNCT05956314What this trial is testingAssessment of KM-001 - Safety, Tolerability, and Efficacy in Patients With PPPK1 or PCWho this might be right forPunctate Palmoplantar Keratoderma Type 1Pachyonychia Congenita Orvida Pharma (formerly Kamari Pharma) 18
Large-scale testing (Phase 3)Study completedNCT03920228What this trial is testingPhase 2/3 Study Evaluating the Safety and Efficacy of PTX-022 in Treatment of Adults With Pachyonychia CongenitaWho this might be right forPachyonychia Congenita Palvella Therapeutics, Inc. 73
Not applicableStudy completedNCT00074685What this trial is testingNational Registry for Ichthyosis and Related DisordersWho this might be right forDarier DiseaseHailey-Hailey DiseaseHyperkeratosis, Epidermolytic+4 more National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 610
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06545695What this trial is testingEpidermal Growth Factor Receptor Inhibition for KeratinopathiesWho this might be right forEpidermolytic IchthyosisPalmoplantar KeratodermaPachyonychia Congenita Northwestern University 44
Early research (Phase 1)Study completedNCT02152007What this trial is testingTopical Sirolimus for the Treatment of Pachyonychia Congenita (PC)Who this might be right forPachyonychia Congenita TransDerm, Inc. 15
Not applicableUnknownNCT01382511What this trial is testingSimvastatin Treatment of Pachyonychia CongenitaWho this might be right forPachyonychia Congenita Tel-Aviv Sourasky Medical Center 10