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Results for “Paroxysmal Nocturnal Haemoglobinuria (PNH)”

190 trials

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Showing 20 of 190 results

Not applicableActive Not RecruitingNCT03047746
What this trial is testing

Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF

Who this might be right for
Acquired Aplastic AnemiaParoxysmal Nocturnal HemoglobinuriaInherited Bone Marrow Failure Syndromes
Children's Hospital of Philadelphia 50
Large-scale testing (Phase 3)Study completedNCT00098280
What this trial is testing

Eculizumab to Treat Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Hemoglobinuria, Paroxysmal
National Heart, Lung, and Blood Institute (NHLBI) 75
Testing effectiveness (Phase 2)Study completedNCT03946748
What this trial is testing

Study to Evaluate the Efficacy and Safety of REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Regeneron Pharmaceuticals 24
Testing effectiveness (Phase 2)Ended earlyNCT04702568
What this trial is testing

A Long-Term Safety Study of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaPNH
BioCryst Pharmaceuticals 19
Large-scale testing (Phase 3)Study completedNCT03056040
What this trial is testing

ALXN1210 Versus Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Alexion Pharmaceuticals, Inc. 202
Large-scale testing (Phase 3)Study completedNCT04820530
What this trial is testing

Study of Efficacy and Safety of Twice Daily Oral Iptacopan (LNP023) in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Novartis Pharmaceuticals 40
Large-scale testing (Phase 3)Study completedNCT00122330
What this trial is testing

Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Who this might be right for
Hemoglobinuria, Paroxysmal
Alexion Pharmaceuticals, Inc. 75
Early research (Phase 1)Study completedNCT06100900
What this trial is testing

Dose Escalation of BCX10013 in Participants with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
BioCryst Pharmaceuticals 8
Large-scale testing (Phase 3)Looking for participantsNCT06933914
What this trial is testing

Long-term Safety and Tolerability of MY008211A Tablets in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Wuhan Createrna Science and Technology Co., Ltd 120
Testing effectiveness (Phase 2)Active Not RecruitingNCT07212426
What this trial is testing

Efficacy, Safety, and Pharmacokinetics of LP-005 Injection in PNH Patients.

Who this might be right for
PNH - Paroxysmal Nocturnal Hemoglobinuria
Longbio Pharma 30
Not applicableLooking for participantsNCT06524726
What this trial is testing

The International PNH Interest Group PNH Registry

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
International PNH Interest Group 2,000
Testing effectiveness (Phase 2)Looking for participantsNCT05876312
What this trial is testing

Safety, Tolerability, PK and PD of ADX-038 in Healthy Participants and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
ADARx Pharmaceuticals, Inc. 50
Large-scale testing (Phase 3)Study completedNCT04679103
What this trial is testing

A Safety and Immunogenicity Study in Long-term Treatment of Eculizumab (JSC "GENERIUM", Russian Federation)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
AO GENERIUM 50
Large-scale testing (Phase 3)Ended earlyNCT03829449
What this trial is testing

RVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
AKARI Therapeutics 15
Testing effectiveness (Phase 2)UnknownNCT01642979
What this trial is testing

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaHemoglobinuriaHemoglobinuria, Paroxysmal+6 more
Institute of Hematology & Blood Diseases Hospital, China 120
Testing effectiveness (Phase 2)Study completedNCT03078582
What this trial is testing

Phase 2 Safety and Efficacy Study of Zilucoplan (RA101495) to Treat PNH Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Ra Pharmaceuticals 26
Not applicableStudy completedNCT04128943
What this trial is testing

Electronic Patient-reported Outcome Monitoring in Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Aplastic AnemiaParoxysmal Nocturnal Hemoglobinuria
University Hospital, Basel, Switzerland 9
Testing effectiveness (Phase 2)Study completedNCT01192399
What this trial is testing

Safety and Efficacy Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Alexion Pharmaceuticals, Inc. 29
Testing effectiveness (Phase 2)Study completedNCT03896152
What this trial is testing

Efficacy, Safety, Pharmacokinetics and Pharmacodynamics Study, Assessing Multiple LNP023 Doses in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Novartis Pharmaceuticals 13
Large-scale testing (Phase 3)Study completedNCT00112983
What this trial is testing

Eculizumab in Treating Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Leukemia
Jonsson Comprehensive Cancer Center
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