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Results for “Parsaclisib”

33 trials

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Showing 20 of 33 results

Large-scale testing (Phase 3)Ended earlyNCT04551066
What this trial is testing

To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)

Who this might be right for
MyelofibrosisPrimary MyelofibrosisPost Essential Thrombocythemia Myelofibrosis+1 more
Incyte Corporation 252
Testing effectiveness (Phase 2)Study completedNCT03144674
What this trial is testing

INCB050465 in Subjects With Relapsed or Refractory Marginal Zone Lymphoma (CITADEL-204)

Who this might be right for
Lymphoma
Incyte Corporation 110
Testing effectiveness (Phase 2)UnknownNCT05238064
What this trial is testing

Parsaclisib in Combination With CHOP in Participants With Previously Untreated PTCL

Who this might be right for
PI3Kδ InhibitorParsaclisibCHOP+1 more
Fudan University 30
Early research (Phase 1)Study completedNCT04831944
What this trial is testing

To Evaluate the Safety, and Pharmacokinetics of Parscaclisib in Participants With Normal Hepatic Function and Hepatic Impairment.

Who this might be right for
Advanced Malignancies
Incyte Corporation 21
Early research (Phase 1)Ended earlyNCT02559492
What this trial is testing

Itacitinib Combined With INCB024360 and/or Itacitinib Combined With INCB050465 in Advanced Solid Tumors

Who this might be right for
Solid Tumors
Incyte Corporation 142
Testing effectiveness (Phase 2)Study completedNCT03538041
What this trial is testing

INCB050465 in Participants With Autoimmune Hemolytic Anemia

Who this might be right for
Autoimmune Hemolytic Anemia
Incyte Corporation 25
Testing effectiveness (Phase 2)Ended earlyNCT02718300
What this trial is testing

INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 74
Testing effectiveness (Phase 2)Study completedNCT04434937
What this trial is testing

Open-Label Study of Parsaclisib, in Japanese Participants With Relapsed or Refractory Follicular Lymphoma (CITADEL-213)

Who this might be right for
Lymphoma
Incyte Biosciences Japan GK 42
Early research (Phase 1)Active Not RecruitingNCT04323956
What this trial is testing

Parsaclisib Plus the Standard Drug Therapy in Patients With Newly Diagnosed, High Risk Diffuse Large B-cell Lymphoma

Who this might be right for
Ann Arbor Stage II Diffuse Large B-Cell LymphomaAnn Arbor Stage II Follicular LymphomaAnn Arbor Stage II Marginal Zone Lymphoma+11 more
Mayo Clinic 50
Testing effectiveness (Phase 2)Study completedNCT02018861
What this trial is testing

A Phase 1/2, Open-Label, Dose Escalation, Safety and Tolerability Study of INCB050465 and Itacitinib in Subjects With Previously Treated B-Cell Malignancies (CITADEL-101)

Who this might be right for
B-Cell Malignancies
Incyte Corporation 88
Testing effectiveness (Phase 2)Active Not RecruitingNCT04661007
What this trial is testing

To Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL)

Who this might be right for
Non Hodgkins LymphomaDiffuse Large B-cell Lymphoma
Incyte Biosciences Japan GK 72
Large-scale testing (Phase 3)Ended earlyNCT05073458
What this trial is testing

Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia

Who this might be right for
Warm Autoimmune Hemolytic Anemia (wAIHA)
Incyte Corporation 13
Early research (Phase 1)Study completedNCT04831996
What this trial is testing

To Evaluate the Safety, and Pharmacokinetics of Parscaclisib in Participants With Normal Renal Function and Renal Impairment.

Who this might be right for
Advanced Malignancies
Incyte Corporation 48
Early research (Phase 1)Study completedNCT02646748
What this trial is testing

Pembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid Tumors

Who this might be right for
Colorectal Cancer (CRC)Endometrial CancerMelanoma+8 more
Incyte Corporation 159
Large-scale testing (Phase 3)Ended earlyNCT04551053
What this trial is testing

To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304)

Who this might be right for
MyelofibrosisPrimary MyelofibrosisPost Essential Thrombocythemia Myelofibrosis+1 more
Incyte Corporation 177
Testing effectiveness (Phase 2)Active Not RecruitingNCT04509700
What this trial is testing

Rollover Study to Provide Continued Treatment for Participants With B-Cell Malignancies Previously Enrolled in Studies of Parsaclisib (INCB050465)

Who this might be right for
B-Cell Malignancies
Incyte Corporation 112
Testing effectiveness (Phase 2)Study completedNCT03126019
What this trial is testing

INCB050465 in Relapsed or Refractory Follicular Lymphoma

Who this might be right for
Lymphoma
Incyte Corporation 126
Early research (Phase 1)Study completedNCT03039114
What this trial is testing

Study Evaluating Safety and Efficacy of INCB050465 Combined With Bendamustine and Obinutuzumab in Relapsed or Refractory Follicular Lymphoma (CITADEL-102)

Who this might be right for
Lymphoma
Incyte Corporation 26
Early research (Phase 1)Study completedNCT03424122
What this trial is testing

INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)

Who this might be right for
B-cell Lymphoma
Incyte Corporation 50
Early research (Phase 1)Study completedNCT04774068
What this trial is testing

Romidepsin and Parsaclisib for the Treatment of Relapsed or Refractory T-Cell Lymphomas

Who this might be right for
Recurrent Anaplastic Large Cell LymphomaRecurrent Mature T-Cell and NK-Cell Non-Hodgkin LymphomaRecurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma+6 more
Walter Hanel 5
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