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Results for “Part 1- Advanced Solid Tumors”

50 trials

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Showing 20 of 50 results

Early research (Phase 1)Active Not RecruitingNCT03401385
What this trial is testing

First-in-human Study of DS-1062a for Advanced Solid Tumors (TROPION-PanTumor01)

Who this might be right for
Hormone Receptor Positive Breast CancerTriple Negative Breast CancerNon-small Cell Lung Cancer
Daiichi Sankyo Co., Ltd. 890
Early research (Phase 1)Looking for participantsNCT07247110
What this trial is testing

A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)

Who this might be right for
Malignant Neoplasm
Merck Sharp & Dohme LLC 250
Testing effectiveness (Phase 2)Looking for participantsNCT07070232
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

Who this might be right for
Advanced Solid Tumor
BioNTech SE 1,438
Early research (Phase 1)Study completedNCT01497470
What this trial is testing

A Clinical Study in Cancer Patients to Investigate the Potential Impact of Custirsen, on the Blood Levels of the Chemotherapeutic Drug, Paclitaxel, When Given Together as Part of a Treatment Regimen

Who this might be right for
Cancer
Achieve Life Sciences 36
Early research (Phase 1)Study completedNCT04423029
What this trial is testing

DF6002 Alone and in Combination With Nivolumab

Who this might be right for
Solid Tumors
Dragonfly Therapeutics 170
Early research (Phase 1)Study completedNCT04887194
What this trial is testing

PK Study to Assess Drug-drug Interaction and QTc Between Sitravatinib and a Cocktail of Substrates

Who this might be right for
Advanced Solid Tumor
Mirati Therapeutics Inc. 40
Early research (Phase 1)Study completedNCT05391022
What this trial is testing

Study Evaluating Food Effect and QTc in Patients With Advanced Malignancies

Who this might be right for
Advanced MalignanciesSolid TumorHematological Malignancy
Constellation Pharmaceuticals 35
Testing effectiveness (Phase 2)Looking for participantsNCT04643418
What this trial is testing

Phase 1/2a Study of MPB-1734 in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor, Unspecified, Adult
MegaPro Biomedical Co. Ltd. 81
Early research (Phase 1)Active Not RecruitingNCT06074497
What this trial is testing

This is an Open Label, Two-part, Multicenter, Phase I Trial to Investigate the Safety, Tolerability, and PK of KGX101 Monotherapy and Combination Therapy With Envafolimab in Patients With Advanced or Metastatic Solid Tumors.

Who this might be right for
Advanced or Metastatic Solid Tumors
Kangabio AUSTRALIA LTD PTY 54
Testing effectiveness (Phase 2)Ended earlyNCT05430555
What this trial is testing

A Phase 1/ 2, First-in-Human, Open-Label, Accelerated-Titration, Two-Part Clinical Trial of TK-8001 in Patients With HLA-A*02:01 Genotype and Advanced-Stage/ Metastatic MAGE-A1+ Solid Tumors

Who this might be right for
Advanced Solid Tumors
T-knife GmbH 23
Early research (Phase 1)Looking for participantsNCT07372625
What this trial is testing

Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

Who this might be right for
TP53 Y220C MutationAdvanced Solid Tumors
PMV Pharmaceuticals, Inc 14
Early research (Phase 1)Looking for participantsNCT05067283
What this trial is testing

Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

Who this might be right for
Advanced Solid Tumors
Merck Sharp & Dohme LLC 830
Early research (Phase 1)Looking for participantsNCT05765851
What this trial is testing

DS-1103a Combination Therapy in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
Daiichi Sankyo 108
Early research (Phase 1)WithdrawnNCT05678283
What this trial is testing

Absorption, Metabolism, and Elimination CC-90010 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bristol-Myers Squibb
Early research (Phase 1)UnknownNCT02637531
What this trial is testing

A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549

Who this might be right for
Advanced Solid Tumors (Part A/B/C/D)Non-small Cell Lung Cancer (Part E)Melanoma (Part E)+5 more
Infinity Pharmaceuticals, Inc. 219
Early research (Phase 1)Study completedNCT02564900
What this trial is testing

Study of DS-8201a in Subjects With Advanced Solid Malignant Tumors

Who this might be right for
Advanced Solid Tumors
Daiichi Sankyo Co., Ltd. 292
Early research (Phase 1)Looking for participantsNCT06815575
What this trial is testing

A Safety and Pharmacokinetics Study of RC220 Combined With Doxorubicin in Adult Participants With Solid Tumours.

Who this might be right for
Solid TumoursAdvanced Solid Tumours
Racura Oncology Ltd 53
Testing effectiveness (Phase 2)Looking for participantsNCT07563738
What this trial is testing

A 2-part Phase 1/2 Open-label Trial on ODM-212

Who this might be right for
MesotheliomaPancreatic CancerNSCLC (Advanced Non-small Cell Lung Cancer)
Orion Corporation, Orion Pharma 229
Early research (Phase 1)Looking for participantsNCT06641908
What this trial is testing

Anti-GD2 ADC M3554 in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
EMD Serono Research & Development Institute, Inc. 65
Testing effectiveness (Phase 2)Looking for participantsNCT07262619
What this trial is testing

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

Who this might be right for
Advanced Solid TumorsMSI-H or dMMR Advanced Solid TumorsMSI-H/dMMR Gastric Cancer+4 more
Eikon Therapeutics 160
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