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Results for “Part 2：B-cell Malignancies”

15 trials

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Showing 15 of 15 results

Early research (Phase 1)Study completedNCT00923169
What this trial is testing

Part 2 of Phase 1 Study of GC1008 to Treat Advanced Melanoma (Part 2 Will Only Accept and Treat Patients With Advanced Malignant Melanoma)

Who this might be right for
Renal Cell Carcinoma
National Cancer Institute (NCI) 9
Testing effectiveness (Phase 2)UnknownNCT04014205
What this trial is testing

Tyrosine Kinase Inhibitor Orelabrutinib (ICP-022) in Patients With r/r B-Cell Malignancies

Who this might be right for
Part 1：r/r B-cell MalignanciesPart 2：B-cell Malignancies
Beijing InnoCare Pharma Tech Co., Ltd. 81
Early research (Phase 1)Ended earlyNCT04543188
What this trial is testing

A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement

Who this might be right for
Malignant MelanomaCarcinoma, Non-Small-Cell LungBrain Neoplasms, Primary+2 more
Pfizer 65
Early research (Phase 1)Looking for participantsNCT06539338
What this trial is testing

Investigate Safety of INT2104 Infusions in Participants Aged 18 Years of Age and Older Who Have B-cell Cancers That Came Back After Previous Treatment

Who this might be right for
Lymphomas Non-Hodgkin's B-CellPrecursor Cell Lymphoblastic Leukemia-Lymphoma
Kite, A Gilead Company 34
Early research (Phase 1)Study completedNCT03010982
What this trial is testing

Open-Label, Multi-Center, Two-Part, Ph1 Study to Characterize the PKs of an Intravenous Micro-Dose of [14C]-Tazemetostat (EPZ 6438) and the ADME of an Oral [14C]-Labeled Dose of Tazemetostat in Subjects With B-Cell Lymphomas or Adv Solid Tumors

Who this might be right for
Diffuse Large B Cell LymphomaPrimary Mediastinal LymphomaMantle-Cell Lymphoma+3 more
Epizyme, Inc. 3
Early research (Phase 1)Study completedNCT01457417
What this trial is testing

DKN-01 in Multiple Myeloma or Advanced Solid Tumors

Who this might be right for
Multiple MyelomaSolid TumorsNon-Small Cell Lung Cancer
Leap Therapeutics, Inc. 32
Early research (Phase 1)Study completedNCT01955668
What this trial is testing

AZD6738 First Time in Patient Multiple Ascending Dose Study

Who this might be right for
11q-deleted Relapsed/Refractory Chronic Lymphocytic Leukaemia (CLL),Prolymphocytic Leukaemia (PLL)B Cell Lymphomas
AstraZeneca 2
Early research (Phase 1)Ended earlyNCT05121103
What this trial is testing

The Safety, Tolerability and Effectiveness of EZM0414 (IPN60210) Investigative Product in Participants With Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Diffuse Large B Cell Lymphoma

Who this might be right for
Multiple Myeloma, RefractoryDiffuse Large B-Cell LymphomaDiffuse Large B Cell Lymphoma Refractory+1 more
Epizyme, Inc. 13
Testing effectiveness (Phase 2)UnknownNCT02968303
What this trial is testing

Induction Therapy With Vemurafenib and Cobimetinib to Optimize Nivolumab and Ipilimumab Therapy

Who this might be right for
Melanoma, Malignant, of Soft Parts
Radboud University Medical Center 200
Early research (Phase 1)Study completedNCT03028103
What this trial is testing

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Who this might be right for
Diffuse Large B Cell LymphomaPrimary Mediastinal LymphomaMantle Cell Lymphoma+2 more
Epizyme, Inc. 32
Early research (Phase 1)Study completedNCT04488016
What this trial is testing

Evaluate Relative Bioavailability, Proton Pump Inhibitor (PPI) (Rabeprazole) Effect, Food Effect and Particle Size Effect of New Acalabrutinib Tablet in Healthy Subjects

Who this might be right for
BioavailabilityB-cell Lymphoid Cancer
AstraZeneca 54
Testing effectiveness (Phase 2)Looking for participantsNCT05533775
What this trial is testing

Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma

Who this might be right for
Mature B-Cell Non-Hodgkin Lymphoma
Hoffmann-La Roche 65
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Early research (Phase 1)Study completedNCT00478725
What this trial is testing

Part A: Radiolabel Study With GW786034 Part B: Single Dose of GW786034

Who this might be right for
Carcinoma, Renal Cell
GlaxoSmithKline 10
Early research (Phase 1)Study completedNCT04537715
What this trial is testing

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Who this might be right for
All MalignanciesAdvanced MalignanciesHematologic Malignancy+9 more
Epizyme, Inc. 42