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Results for “Part A and B: Advanced Solid Malignancies”

13 trials

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Showing 13 of 13 results

Early research (Phase 1)Ended earlyNCT02317419
What this trial is testing

RO6927005 Either As Monotherapy (Part A) or in Combination With Gemcitabine and Nab-Paclitaxel (Part B) to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Clinical Activity in Patients With Mesothelin-positive Metastatic and/or Locally Advanced Malignant Solid Tumors

Who this might be right for
Cancer
Hoffmann-La Roche 15
Early research (Phase 1)UnknownNCT02637531
What this trial is testing

A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549

Who this might be right for
Advanced Solid Tumors (Part A/B/C/D)Non-small Cell Lung Cancer (Part E)Melanoma (Part E)+5 more
Infinity Pharmaceuticals, Inc. 219
Early research (Phase 1)Study completedNCT00478725
What this trial is testing

Part A: Radiolabel Study With GW786034 Part B: Single Dose of GW786034

Who this might be right for
Carcinoma, Renal Cell
GlaxoSmithKline 10
Early research (Phase 1)Active Not RecruitingNCT06870487
What this trial is testing

Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers

Who this might be right for
Peripheral T Cell LymphomaDiffuse Large B-cell LymphomaClassical Hodgkin Lymphoma+3 more
Pfizer 6
Early research (Phase 1)Study completedNCT02141347
What this trial is testing

Ph1 to Assess Safety, Tolerability of Tremelimumab/ Tremelimumab+MEDI4736 in Japanese Solid Malignancies/ Mesothelioma

Who this might be right for
Part A and B: Advanced Solid MalignanciesPart C: Malignant Mesothelioma
AstraZeneca 65
Early research (Phase 1)Ended earlyNCT02979392
What this trial is testing

Phase I Study of TENPA in Advanced Solid Cancer

Who this might be right for
Advanced Solid Tumor
Yung-Jue Bang 19
Early research (Phase 1)Study completedNCT01457417
What this trial is testing

DKN-01 in Multiple Myeloma or Advanced Solid Tumors

Who this might be right for
Multiple MyelomaSolid TumorsNon-Small Cell Lung Cancer
Leap Therapeutics, Inc. 32
Early research (Phase 1)Study completedNCT00809133
What this trial is testing

Trial Exploring Afatinib (BIBW 2992) + Paclitaxel (Part A), Afatinib + Paclitaxel + Bevacizumab (Part B), Afatinib + Carboplatin (Part C) and Afatinib+ Paclitaxel +Carboplatin(Part D) in Patients With Advanced Solid Tumours

Who this might be right for
Neoplasms
Boehringer Ingelheim 83
Early research (Phase 1)UnknownNCT02352571
What this trial is testing

Safety Study of GC1118 (Recombinant Human Anti-EGFR Antibody) in Patients With Advanced Solid Cancer

Who this might be right for
Neoplasm MetastasisGastric CancerColorectal Cancer
Green Cross Corporation 72
Early research (Phase 1)Study completedNCT01987362
What this trial is testing

A Two Part Study of RO6870810. Dose-Escalation Study in Participants With Advanced Solid Tumors and Expansion Study in Participants With Selected Malignancies

Who this might be right for
Solid Tumors, Advanced Solid Tumors
Hoffmann-La Roche 52
Early research (Phase 1)Study completedNCT03028103
What this trial is testing

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Who this might be right for
Diffuse Large B Cell LymphomaPrimary Mediastinal LymphomaMantle Cell Lymphoma+2 more
Epizyme, Inc. 32
Early research (Phase 1)Study completedNCT01482377
What this trial is testing

RO5479599 Alone or in Combination With Cetuximab or Erlotinib in Participants With Metastatic and/or Locally Advanced Malignant Human Epidermal Growth Factor Receptor (HER3) Expressing Solid Tumors of Epithelial Cell Origin

Who this might be right for
Neoplasms
Hoffmann-La Roche 145
Early research (Phase 1)Study completedNCT04537715
What this trial is testing

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Who this might be right for
All MalignanciesAdvanced MalignanciesHematologic Malignancy+9 more
Epizyme, Inc. 42