Not applicableLooking for participantsNCT02325674What this trial is testingMEASuRE: Metreleptin Effectiveness And Safety RegistryWho this might be right forGeneralised LipodystrophyPartial Lipodystrophy Amryt Pharma 100
Not applicableLooking for participantsNCT05996536What this trial is testingFeasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD)Who this might be right forLipodystrophy National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 14
Large-scale testing (Phase 3)Looking for participantsNCT06679270What this trial is testingOpen-label Extension Study to Evaluate Metreleptin in Patients With Partial LipodystrophyWho this might be right forFamilial Partial Lipodystrophy Amryt Pharma 24
Testing effectiveness (Phase 2)Study completedNCT03508687What this trial is testingStudy of Gemcabene in Adults With FPLDWho this might be right forFamilial Partial LipodystrophyHypertriglyceridemiaFatty Liver+1 more Elif Oral 5
Not applicableStudy completedNCT07090629What this trial is testingThe Benefits of the Measureof Epicardial Adipose Tissue During Coronary Calcium Assessment of the Refine Cardiovascular Risk Assessment at Reunion Island.Who this might be right forHigh CholesterolLipodystrophy, Familial PartialDiabetes Centre Hospitalier Universitaire de la Réunion 126
Not applicableWithdrawnNCT04056000What this trial is testingLipodystrophy and Fat Metabolism During ExerciseWho this might be right forHealthyLipodystrophy, Familial Partial University of Exeter
Testing effectiveness (Phase 2)Study completedNCT03514420What this trial is testingStudy of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Partial Lipodystrophy (FPL)Who this might be right forFamilial Partial Lipodystrophy Akcea Therapeutics 4
Large-scale testing (Phase 3)Not Yet RecruitingNCT07220785What this trial is testingEfficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized LipodystrophyWho this might be right forGeneralized Lipodystrophy Regeneron Pharmaceuticals 28
Testing effectiveness (Phase 2)Looking for participantsNCT05470504What this trial is testingStudy of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin ResistanceWho this might be right forInsulin Receptor MutationPartial Lipodystrophy National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 25
Testing effectiveness (Phase 2)Study completedNCT02639286What this trial is testingEfficacy, Safety and Tolerability of ISIS 304801 in People With Partial Lipodystrophy With an Open-Label ExtensionWho this might be right forLipodystrophy National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 5
Post-approval studies (Phase 4)Looking for participantsNCT06484868What this trial is testingOpen-label Study to Evaluate Metreleptin in Patients With Partial LipodystrophyWho this might be right forPartial Lipodystrophy Amryt Pharma 12
Not applicableStudy completedNCT02577952What this trial is testingLipodystrophy Connect Patient RegistryWho this might be right forLipodystrophy PatientCrossroads 257
Not applicableUnknownNCT06107439What this trial is testingImpact of Lipodystrophy on the Inflammatory State of Non-diabetic Dunnigan Reunion Island SubjectsWho this might be right forLipodystrophyDunnigan Syndrome Centre Hospitalier Universitaire de la Réunion 80
Large-scale testing (Phase 3)Active Not RecruitingNCT05164341What this trial is testingStudy to Evaluate the Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With PLWho this might be right forPartial Lipodystrophy Amryt Pharma 69
Testing effectiveness (Phase 2)Study completedNCT02430077What this trial is testingPhase 2 Study of Obeticholic Acid for Lipodystrophy PatientsWho this might be right forFamilial Partial Lipodystrophy Abhimanyu Garg 10
Large-scale testing (Phase 3)Study completedNCT00896298What this trial is testingTrial of Leptin Replacement Therapy in Patients With LipodystrophyWho this might be right forHypoleptinemiaGeneralized LipodystrophyPartial Lipodystrophy+1 more University of Texas Southwestern Medical Center 25
Not applicableAvailableNCT02404896What this trial is testingExpanded Access Metreleptin StudyWho this might be right forFamilial Partial Lipodystrophy University of Michigan
Testing effectiveness (Phase 2)Looking for participantsNCT07091734What this trial is testingTirzepatide for Partial Lipodystrophy Treatment: A New Horizon in 2024Who this might be right forLipodystrophy, Partial University of Michigan 32
Large-scale testing (Phase 3)Ended earlyNCT02527343What this trial is testingThe BROADEN Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Partial LipodystrophyWho this might be right forFamilial Partial Lipodystrophy Akcea Therapeutics 40
Testing effectiveness (Phase 2)Study completedNCT03262610What this trial is testingSetmelanotide in a Single Patient With Partial LipodystrophyWho this might be right forHypertriglyceridemiaObesity Rhythm Pharmaceuticals, Inc. 1