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Results for “Partial Lipodystrophy”

32 trials

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Showing 20 of 32 results

Large-scale testing (Phase 3)Active Not RecruitingNCT06548100
What this trial is testing

The Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 9
Post-approval studies (Phase 4)Looking for participantsNCT06484868
What this trial is testing

Open-label Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

Who this might be right for
Partial Lipodystrophy
Amryt Pharma 12
Not applicableStudy completedNCT05424913
What this trial is testing

Exploratory Study of the Relationships Between the Biomarkers of Inflammation, Lipidome and Insulin Resistance and Disorders of Glycemic Regulation in a Cohort of Insulin-resistant Subjects Due to Excess Weight or Dunnigan's Lipodystrophy

Who this might be right for
LipodystrophyDunnigan Syndrome
Centre Hospitalier Universitaire de la Réunion 150
Large-scale testing (Phase 3)Active Not RecruitingNCT05164341
What this trial is testing

Study to Evaluate the Safety and Efficacy of Daily Subcutaneous Metreleptin Treatment in Subjects With PL

Who this might be right for
Partial Lipodystrophy
Amryt Pharma 69
Testing effectiveness (Phase 2)Study completedNCT02654977
What this trial is testing

CLINICAL PROTOCOL to Investigate the Long-term Safety and Efficacy of Metreleptin in Various Forms of Partial Lipodystrophy

Who this might be right for
Familial Partial LipodystrophyNonalcoholic SteatohepatitisNAFLD
University of Michigan 11
Testing effectiveness (Phase 2)Study completedNCT02430077
What this trial is testing

Phase 2 Study of Obeticholic Acid for Lipodystrophy Patients

Who this might be right for
Familial Partial Lipodystrophy
Abhimanyu Garg 10
Not applicableStudy completedNCT02858830
What this trial is testing

Familial Partial Lipodystrophy Study

Who this might be right for
Lipodystrophy, Familial Partial
Mayo Clinic 12
Large-scale testing (Phase 3)Looking for participantsNCT07220785
What this trial is testing

Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized Lipodystrophy

Who this might be right for
Generalized Lipodystrophy
Regeneron Pharmaceuticals 28
Testing effectiveness (Phase 2)Study completedNCT03514420
What this trial is testing

Study of AKCEA-ANGPTL3-LRx (ISIS 703802) in Participants With Familial Partial Lipodystrophy (FPL)

Who this might be right for
Familial Partial Lipodystrophy
Akcea Therapeutics 4
Testing effectiveness (Phase 2)Study completedNCT02639286
What this trial is testing

Efficacy, Safety and Tolerability of ISIS 304801 in People With Partial Lipodystrophy With an Open-Label Extension

Who this might be right for
Lipodystrophy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 5
Not applicableLooking for participantsNCT03900286
What this trial is testing

Low Energy Diet and Familial Partial Lipodystrophy

Who this might be right for
LipodystrophyDiabetesDiet Modification
Cambridge University Hospitals NHS Foundation Trust 20
Testing effectiveness (Phase 2)Ended earlyNCT05088460
What this trial is testing

Examine the Effects of the Leptin Receptor (LEPR) Agonist Antibody REGN4461 in Adult Patients With Familial Partial Lipodystrophy (FPLD)

Who this might be right for
Familial Partial LipodystrophyMetabolic Abnormalities
Regeneron Pharmaceuticals 20
Not applicableStudy completedNCT02577952
What this trial is testing

Lipodystrophy Connect Patient Registry

Who this might be right for
Lipodystrophy
PatientCrossroads 257
Not applicableNot Yet RecruitingNCT07412028
What this trial is testing

Identification of Women With Severe Insulin Resistant Syndromes of Genetic Origin Among Patients With "Classic" Polycystic Ovary Syndrome (PCOS)

Who this might be right for
Polycystic Ovary SyndromeFamilial Partial LipodystrophyLMNA (LaMin Nuclear A) Related Disorders
Assistance Publique - Hôpitaux de Paris 81
Large-scale testing (Phase 3)Study completedNCT00896298
What this trial is testing

Trial of Leptin Replacement Therapy in Patients With Lipodystrophy

Who this might be right for
HypoleptinemiaGeneralized LipodystrophyPartial Lipodystrophy+1 more
University of Texas Southwestern Medical Center 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT02262806
What this trial is testing

Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy

Who this might be right for
DiabetesLipodystrophyHyperlipidemia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 29
Not applicableWithdrawnNCT04056000
What this trial is testing

Lipodystrophy and Fat Metabolism During Exercise

Who this might be right for
HealthyLipodystrophy, Familial Partial
University of Exeter
Not applicableUnknownNCT06107439
What this trial is testing

Impact of Lipodystrophy on the Inflammatory State of Non-diabetic Dunnigan Reunion Island Subjects

Who this might be right for
LipodystrophyDunnigan Syndrome
Centre Hospitalier Universitaire de la Réunion 80
Large-scale testing (Phase 3)Looking for participantsNCT06679270
What this trial is testing

Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

Who this might be right for
Familial Partial Lipodystrophy
Amryt Pharma 24
Not applicableLooking for participantsNCT07516496
What this trial is testing

Metabolic Phenotyping in vEDS

Who this might be right for
Vascular Ehlers-Danlos SyndromeVascular Ehlers Danlos SyndromeVascular EDS (vEDS)
Cambridge University Hospitals NHS Foundation Trust 15
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