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Results for “Participants With Advanced Solid Tumor Malignancies”

818 trials

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Showing 20 of 818 results

Early research (Phase 1)Looking for participantsNCT05176483
What this trial is testing

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Metastatic Castration-Resistant Prostate Cancer (mCRPC)Urothelial Carcinoma (UC)+7 more
Exelixis 1,314
Testing effectiveness (Phase 2)Looking for participantsNCT07446855
What this trial is testing

Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours

Who this might be right for
Solid Tumours
AstraZeneca 180
Testing effectiveness (Phase 2)Study completedNCT05661578
What this trial is testing

Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors

Who this might be right for
PD-L1-selected Solid Tumors
Hoffmann-La Roche 64
Early research (Phase 1)Looking for participantsNCT06265688
What this trial is testing

First In Human Study of CX-2051 in Advanced Solid Tumors

Who this might be right for
Solid Tumor, Adult
CytomX Therapeutics 160
Testing effectiveness (Phase 2)Active Not RecruitingNCT05585320
What this trial is testing

A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorPancreatic AdenocarcinomaMalignant Melanoma (Cutaneous)+1 more
Immuneering Corporation 209
Testing effectiveness (Phase 2)Ended earlyNCT06024174
What this trial is testing

BMS-986466 With Adagrasib With or Without Cetuximab in Participants With Kirsten Rat Sarcoma Virus Glycine 12 to Cysteine (KRAS G12C)-Mutant Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bristol-Myers Squibb 5
Early research (Phase 1)UnknownNCT06019013
What this trial is testing

QLF3108 in Participants With Advanced Solid Tumor

Who this might be right for
Advanced Solid Tumor
Qilu Pharmaceutical Co., Ltd. 78
Early research (Phase 1)Looking for participantsNCT06659341
What this trial is testing

A Phase I Study of BAY3498264 Given Together With Sotorasib in Participants Who Have Advanced Solid Cancers With Specific Genetic Changes Called KRASG12C Mutation

Who this might be right for
Advanced Solid Tumors Harboring KRAS G12C Mutation
Bayer 104
Early research (Phase 1)Looking for participantsNCT07470853
What this trial is testing

MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

Who this might be right for
PROCPlatinum Resistant Ovarian CancerEndometrial Cancer
Whitehawk Therapeutics, Inc. 265
Early research (Phase 1)Looking for participantsNCT06873659
What this trial is testing

SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors

Who this might be right for
Solid TumorGastric CancerLiver Cancer
Qurgen Inc. 96
Early research (Phase 1)Study completedNCT02350673
What this trial is testing

Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 70
Early research (Phase 1)Study completedNCT03739931
What this trial is testing

Dose Escalation Study of mRNA-2752 for Intratumoral Injection to Participants in Advanced Malignancies

Who this might be right for
Dose Escalation: Relapsed/Refractory Solid Tumor Malignancies or LymphomaDose Expansion: Triple Negative Breast Cancer, HNSCC, Non-Hodgkins, Urothelial Cancer, Immune Checkpoint Refractory Melanoma, and NSCLC Lymphoma
ModernaTX, Inc. 134
Early research (Phase 1)Ended earlyNCT04099277
What this trial is testing

LY3435151 in Participants With Solid Tumors

Who this might be right for
Solid TumorTriple-negative Breast CancerGastric Adenocarcinoma+6 more
Eli Lilly and Company 2
Testing effectiveness (Phase 2)Looking for participantsNCT07410494
What this trial is testing

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Who this might be right for
CancerBreast CancerNon-Small Cell Lung Cancer (NSCLC)+10 more
Essen Biotech 85
Early research (Phase 1)Ended earlyNCT04800822
What this trial is testing

PF-07284892 in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Pfizer 53
Early research (Phase 1)Looking for participantsNCT06726369
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of MK-6204 (SKB535) for Injection in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. 90
Early research (Phase 1)Looking for participantsNCT06400472
What this trial is testing

LY4170156 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Ovarian NeoplasmsEndometrial NeoplasmsUterine Cervical Neoplasms+4 more
Eli Lilly and Company 495
Early research (Phase 1)Looking for participantsNCT07114601
What this trial is testing

LY4257496 in Participants With Cancer (OMNIRAY)

Who this might be right for
Breast NeoplasmsColorectal NeoplasmsProstate Neoplasm+4 more
Eli Lilly and Company 421
Early research (Phase 1)Study completedNCT03311477
What this trial is testing

Evaluate the Safety and Pharmacokinetics ABBV-399 in Japanese Participants With Solid Tumors

Who this might be right for
Advanced Solid Tumors Cancer
AbbVie 9
Early research (Phase 1)Looking for participantsNCT06179160
What this trial is testing

Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Who this might be right for
Solid Tumors
Incyte Corporation 710
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