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Results for “Participants With Advanced Solid Tumor Malignancies”

784 trials

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Showing 20 of 784 results

Early research (Phase 1)Looking for participantsNCT06815575
What this trial is testing

A Safety and Pharmacokinetics Study of RC220 Combined With Doxorubicin in Adult Participants With Solid Tumours.

Who this might be right for
Solid TumoursAdvanced Solid Tumours
Race Oncology Ltd 53
Early research (Phase 1)Looking for participantsNCT05464030
What this trial is testing

Anti-CEACAM5 ADC M9140 in Advanced Solid Tumors (PROCEADE-CRC-01)

Who this might be right for
Colorectal Cancer
EMD Serono Research & Development Institute, Inc. 200
Early research (Phase 1)Study completedNCT03000257
What this trial is testing

Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
AbbVie 182
Early research (Phase 1)Ended earlyNCT02784795
What this trial is testing

LY3039478 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Solid TumorBreast CancerColon Cancer+2 more
Eli Lilly and Company 94
Testing effectiveness (Phase 2)Study completedNCT03037385
What this trial is testing

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors

Who this might be right for
RET-altered Non Small Cell Lung CancerMedullary Thyroid CancerRET-altered Papillary Thyroid Cancer+37 more
Hoffmann-La Roche 590
Early research (Phase 1)Active Not RecruitingNCT04794699
What this trial is testing

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Who this might be right for
Solid Tumor
IDEAYA Biosciences 169
Early research (Phase 1)Active Not RecruitingNCT05076552
What this trial is testing

Assess the Safety, Pharmacokinetics, and Antitumor Activity of Oral TACH101 in Participants With Advanced or Metastatic Cancer

Who this might be right for
Advanced CancerMetastatic Solid TumorSolid Tumor
Tachyon Therapeutics, Inc. 30
Testing effectiveness (Phase 2)Looking for participantsNCT07510828
What this trial is testing

PRISM-NK: Precision-Matched Allogeneic Single- or Dual-Target CAR-NK Cells for Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Beijing Biotech 60
Early research (Phase 1)Looking for participantsNCT06784193
What this trial is testing

Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic ER+ HER2- Breast Cancer (mBC)Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)Advanced or Metastatic Castration-Resistant Prostate Cancer (mCRPC)+3 more
Olema Pharmaceuticals, Inc. 180
Early research (Phase 1)Looking for participantsNCT06507306
What this trial is testing

Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Who this might be right for
Solid Tumor, Adult
Kumquat Biosciences Inc. 100
Early research (Phase 1)Looking for participantsNCT07321106
What this trial is testing

Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

Who this might be right for
Colorectal CancerColorectal Cancer (CRC)Colorectal (Colon or Rectal) Cancer+4 more
Cartography Biosciences 80
Testing effectiveness (Phase 2)Ended earlyNCT05397171
What this trial is testing

A First-in-human Study to Evaluate the Safety and Tolerability of AZD8853 in Participants With Selected Advanced/Metastatic Solid Tumours

Who this might be right for
Urinary Bladder NeoplasmsColorectal CancerCarcinoma, Non-Small-Cell Lung
AstraZeneca 17
Early research (Phase 1)Study completedNCT02054806
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-028/KEYNOTE-28)

Who this might be right for
Solid Tumor
Merck Sharp & Dohme LLC 477
Testing effectiveness (Phase 2)Active Not RecruitingNCT03742895
What this trial is testing

Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002)

Who this might be right for
Advanced Solid Neoplasms
Merck Sharp & Dohme LLC 326
Early research (Phase 1)Looking for participantsNCT07107230
What this trial is testing

JNJ-95437446 in Participants With Advanced-Stage Solid Tumors

Who this might be right for
Colorectal Neoplasms
Janssen Research & Development, LLC 380
Early research (Phase 1)Ended earlyNCT05631327
What this trial is testing

A JZP341 Study in Adult Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorMetastatic Solid Tumor
Jazz Pharmaceuticals 12
Early research (Phase 1)Looking for participantsNCT06120283
What this trial is testing

BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorAdvanced Breast CancerMetastatic Breast Cancer+6 more
BeOne Medicines 399
Early research (Phase 1)Study completedNCT01703481
What this trial is testing

Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Adult Participants With Advanced or Refractory Solid Tumors or Lymphoma

Who this might be right for
Tumor or Lymphoma
Janssen Research & Development, LLC 188
Early research (Phase 1)Ended earlyNCT04267939
What this trial is testing

ATR Inhibitor Elimusertib (BAY1895344) Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

Who this might be right for
Advanced Solid Tumors (Excluding Prostate Cancer)Ovarian Cancer
Bayer 14
Early research (Phase 1)Study completedNCT02000934
What this trial is testing

TAK-659 in Adult Participants With Advanced Solid Tumor and Lymphoma Malignancies

Who this might be right for
Advanced Solid Tumor and Lymphoma Malignancies
Calithera Biosciences, Inc 143
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