Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Participants With Advanced Solid Tumor Malignancies”

870 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 870 results

Early research (Phase 1)Looking for participantsNCT06723236
What this trial is testing

MGC028 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsNSCLC AdenocarcinomaCholangiocarcinoma+2 more
MacroGenics 124
Testing effectiveness (Phase 2)Study completedNCT04632992
What this trial is testing

A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response

Who this might be right for
Advanced Unresectable or Metastatic Solid Malignancy
Genentech, Inc. 252
Testing effectiveness (Phase 2)Active Not RecruitingNCT05262400
What this trial is testing

Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors

Who this might be right for
Breast CancerSolid Tumors
Pfizer 235
Early research (Phase 1)Study completedNCT01058707
What this trial is testing

Dose Escalation Study of MLN0128 in Participants With Advanced Malignancies

Who this might be right for
Advanced Solid Malignancies
Millennium Pharmaceuticals, Inc. 198
Early research (Phase 1)Not Yet RecruitingNCT07836036
What this trial is testing

Evaluation of RAS Inhibitor Treatment in Participants With Advanced or Metastatic Solid Tumors Harboring RAS Mutations

Who this might be right for
Solid TumorRAS Mutation
Jiangsu Aosaikang Pharmaceutical Co., Ltd. 200
Early research (Phase 1)Looking for participantsNCT06598800
What this trial is testing

Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor
BeOne Medicines 153
Early research (Phase 1)Study completedNCT01294735
What this trial is testing

Study of the Safety and Efficacy of MK-4827 Given With Temozolomide in Participants With Advanced Cancer (MK-4827-014 AM1)

Who this might be right for
Recurrence of Solid TumorGlioblastoma MultiformeMelanoma
Merck Sharp & Dohme LLC 19
Early research (Phase 1)Active Not RecruitingNCT06421935
What this trial is testing

M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)

Who this might be right for
Advanced Solid Tumor
EMD Serono Research & Development Institute, Inc. 60
Early research (Phase 1)Ended earlyNCT03435250
What this trial is testing

Study of AG-270 in Participants With Advanced Solid Tumors or Lymphoma With MTAP Loss

Who this might be right for
Advanced Solid TumorsLymphoma
Institut de Recherches Internationales Servier 123
Testing effectiveness (Phase 2)Study completedNCT02810418
What this trial is testing

Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination With Nab-Paclitaxel in People With Previously Treated Metastatic and/or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors

Who this might be right for
NeoplasmsPancreatic Neoplasms
National Cancer Institute (NCI) 40
Early research (Phase 1)Study completedNCT04087018
What this trial is testing

Study to Evaluate Safety and Clinical Activity of AB122 in Biomarker Selected Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Arcus Biosciences, Inc. 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT06220318
What this trial is testing

Assessment of the Safety and Efficacy of C019199 Plus Sintilimab in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Fujian Haixi Pharmaceuticals Co., Ltd. 155
Early research (Phase 1)Ended earlyNCT06540066
What this trial is testing

BGB-B3227 Alone and in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced CancerAdvanced Solid TumorMetastatic Cancer+1 more
BeiGene 35
Early research (Phase 1)Looking for participantsNCT06686745
What this trial is testing

Study of SIM0508 Alone and in Combination in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Jiangsu Simcere Pharmaceutical Co., Ltd. 130
Early research (Phase 1)Ended earlyNCT05061537
What this trial is testing

Study of PF-07263689 in Participants With Selected Advanced Solid Tumors

Who this might be right for
Renal Cell CancerMelanomaNon-Small-Cell Lung Cancer+7 more
Pfizer 13
Early research (Phase 1)Ended earlyNCT06466187
What this trial is testing

SGN-MesoC2 in Advanced Solid Tumors

Who this might be right for
Carcinoma, Non-Small-Cell LungOvarian NeoplasmsPancreatic Adenocarcinoma+4 more
Seagen, a wholly owned subsidiary of Pfizer 19
Testing effectiveness (Phase 2)Ended earlyNCT03386721
What this trial is testing

Basket Study to Evaluate the Therapeutic Activity of Simlukafusp Alfa as a Combination Therapy in Participants With Advanced and/or Metastatic Solid Tumors

Who this might be right for
Advanced/Metastatic Head and Neck, Oesophageal and Cervical Cancers
Hoffmann-La Roche 256
Early research (Phase 1)Ended earlyNCT04158583
What this trial is testing

Evaluate the Safety and Tolerability of RO7296682 in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumors
Hoffmann-La Roche 76
Testing effectiveness (Phase 2)Study completedNCT02737475
What this trial is testing

An Investigational Immuno-Therapy Study of Experimental Medication BMS-986178 by Itself or in Combination With Nivolumab and/or Ipilimumab in Participants With Solid Cancers That Are Advanced or Have Spread

Who this might be right for
Advanced Cancer
Bristol-Myers Squibb 166
Early research (Phase 1)Looking for participantsNCT07114601
What this trial is testing

LY4257496 in Participants With Cancer (OMNIRAY)

Who this might be right for
Breast NeoplasmsColorectal NeoplasmsProstate Neoplasm+4 more
Eli Lilly and Company 421
Next Page