Not applicableUnknownNCT01032785What this trial is testingTiming of Closure of Patent Foramen Ovale Following BirthWho this might be right forClosure of the Foramen Ovale and Ductus Arteriosus Wolfson Medical Center 100
Testing effectiveness (Phase 2)Ended earlyNCT00505570What this trial is testingPRIMA PFO Migraine TrialWho this might be right forMigraineMigraine With AuraPatent Foramen Ovale+1 more Abbott Medical Devices 107
Large-scale testing (Phase 3)Study completedNCT00562289What this trial is testingPatent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke RecurrenceWho this might be right forIschemic StrokePatent Foramen OvaleAtrial Septal Aneurysm+1 more Assistance Publique - Hôpitaux de Paris 664
Not applicableStudy completedNCT04950192What this trial is testingPhilips Intracardiac Echocardiography (ICE) Clinical RegistryWho this might be right forAtrial FibrillationStrokeValve Disease, Heart+5 more Philips Clinical & Medical Affairs Global 155
Not applicableUnknownNCT00983723What this trial is testingClinical Proteomic Research for the BrainWho this might be right forIschemic Brain InjuryStrokeHealthy Individual+2 more Massachusetts General Hospital 750
Not applicableApproved For MarketingNCT00584064What this trial is testingEmergency/Compassionate Use PFO OccluderWho this might be right forPatent Foramen OvalePFO Abbott Medical Devices
Not applicableLooking for participantsNCT05238610What this trial is testingProspective Registry of Elderly ESUS With PFOWho this might be right forEmbolic Stroke of Undetermined Source Asan Medical Center 1,200
Not applicableNot Yet RecruitingNCT07726927What this trial is testingSafety and Efficacy of the Patent Foramen Ovale Suture System for the Closure of Patent Foramen OvaleWho this might be right forPatent Foramen Ovale (PFO) Shenzhen Bihe Medical Co., Ltd 244
Not applicableUnknownNCT00196027What this trial is testingParadigm I Clinical Trial: Study of the PFX Closure System in Subjects With Cryptogenic Stroke, Transient Ischemia Attack or Paradoxical EmbolismWho this might be right forPatent Foramen Ovale Cierra 40
Not applicableUnknownNCT03373929What this trial is testingStitch Closure of PFO and Septal RepairWho this might be right forForamen Ovale, PatentSeptal Defect, AtrialSeptal Defect, Heart HeartStitch.Com 250
Testing effectiveness (Phase 2)WithdrawnNCT02378623What this trial is testingPatients With Patent Foramen Ovale and Endocardial Device Leads on Apixaban for Prevention of Paradoxical EmboliWho this might be right forPatent Foramen OvaleCardiac Implantable Electronic Device Mayo Clinic
Not applicableLooking for participantsNCT05907694What this trial is testingMedical Treatment With or Without Transcatheter Patent Foramen Ovale ClosureWho this might be right forPatent Foramen OvaleCryptogenic StrokeOlder Patients+2 more Josep Rodes-Cabau 714
Not applicableActive Not RecruitingNCT04738071What this trial is testingInternational Multicenter Patent foRamen OVale & strokE (IMPROVE) RegistryWho this might be right forStrokePatent Foramen OvaleAtrial Fibrillation+1 more Luciano A. Sposato 3,730
Not applicableNot Yet RecruitingNCT07742540What this trial is testingThe Cardiovascular Effects of Patent Foramen Ovale in HypoxiaWho this might be right forPatent Foramen Ovale (PFO)High Altitude Pulmonary Edema University of Texas Southwestern Medical Center 50
Not applicableUnknownNCT06046508What this trial is testingMigraine With Aura and Patent Foramen Ovale: Identification of Biomarkers to Select Patients In Whom Intervention Would Be Beneficial (MANET)Who this might be right forMigraine HeadachePFO - Patent Foramen Ovale Centro Cardiologico Monzino 120
Not applicableStudy completedNCT03377465What this trial is testingBiomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and PrognosisWho this might be right forEmbolic Stroke of Undetermined SourceIschemic StrokeAtrial Fibrillation and Flutter+4 more Medical University of Lodz 100
Not applicableStudy completedNCT04433520What this trial is testingTrevisio Post-Approval StudyWho this might be right forPFO - Patent Foramen OvaleASD - Atrial Septal DefectVSD - Muscular Ventricular Septal Defect+1 more Abbott Medical Devices 254
Not applicableEnded earlyNCT04100135What this trial is testingGORE® CARDIOFORM Septal Occluder Migraine Clinical StudyWho this might be right forMigrainePatent Foramen OvalePFO - Patent Foramen Ovale W.L.Gore & Associates 7
Post-approval studies (Phase 4)UnknownNCT01550588What this trial is testingDevice Closure Versus Medical Therapy for Cryptogenic Stroke Patients With High-Risk Patent Foramen Ovale (DEFENSE-PFO)Who this might be right forPatent Foramen Ovale Jae-Kwan Song 210
Not applicableActive Not RecruitingNCT03828825What this trial is testingEvaluation of the Efficacy and Safety of a Simplified Procedure for the Percutaneous Closure of the Patent Foramen OvaleWho this might be right forPatent Foramen Ovale Fondation Hôpital Saint-Joseph 279