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Results for “Pathologic Stage IV Cutaneous Melanoma AJCC V8”

46 trials

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Showing 20 of 46 results

Early research (Phase 1)WithdrawnNCT06626256
What this trial is testing

STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma

Who this might be right for
Locally Advanced Cervical CarcinomaLocally Advanced Colorectal CarcinomaLocally Advanced Malignant Solid Neoplasm+24 more
City of Hope Medical Center
Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Active Not RecruitingNCT04940299
What this trial is testing

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Bladder Carcinoma+39 more
M.D. Anderson Cancer Center 35
Testing effectiveness (Phase 2)Ended earlyNCT04789668
What this trial is testing

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Hematopoietic and Lymphoid Cell Neoplasm+11 more
M.D. Anderson Cancer Center 8
Early research (Phase 1)Looking for participantsNCT05098210
What this trial is testing

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Cutaneous Melanoma+22 more
Fred Hutchinson Cancer Center 25
Testing effectiveness (Phase 2)Ended earlyNCT04902040
What this trial is testing

Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies

Who this might be right for
Advanced Bladder CarcinomaAdvanced Lung Non-Small Cell CarcinomaAdvanced Malignant Solid Neoplasm+32 more
M.D. Anderson Cancer Center 19
Early research (Phase 1)Looking for participantsNCT04119024
What this trial is testing

Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

Who this might be right for
Metastatic Malignant Solid NeoplasmMetastatic MelanomaPathologic Stage IIIC Cutaneous Melanoma AJCC v8+14 more
Anusha Kalbasi 18
Early research (Phase 1)Active Not RecruitingNCT02298959
What this trial is testing

Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Colorectal CarcinomaMetastatic Malignant Solid Neoplasm+12 more
National Cancer Institute (NCI) 59
Testing effectiveness (Phase 2)Study completedNCT03873818
What this trial is testing

Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Malignant Neoplasm in the BrainMetastatic Melanoma+1 more
M.D. Anderson Cancer Center 24
Early research (Phase 1)Looking for participantsNCT05039801
What this trial is testing

IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors

Who this might be right for
Advanced Endometrial CarcinomaAdvanced Head and Neck Squamous Cell CarcinomaAdvanced Malignant Solid Neoplasm+35 more
M.D. Anderson Cancer Center 54
Not applicableLooking for participantsNCT06075524
What this trial is testing

Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Lung Carcinoma+7 more
Mayo Clinic 500
Early research (Phase 1)Study completedNCT03590054
What this trial is testing

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

Who this might be right for
Stage III Cutaneous MelanomaStage IV Cutaneous MelanomaLocally Advanced Melanoma+18 more
Rahul Aggarwal 35
Testing effectiveness (Phase 2)Ended earlyNCT04527549
What this trial is testing

Testing Dabrafenib and Trametinib With or Without Hydroxychloroquine in Stage IIIC or IV BRAF V600E/K Melanoma

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced MelanomaPathologic Stage IIIC Cutaneous Melanoma AJCC v8+2 more
ECOG-ACRIN Cancer Research Group 5
Testing effectiveness (Phase 2)Ended earlyNCT04375527
What this trial is testing

Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC V8Clinical Stage IV Cutaneous Melanoma AJCC V8Locally Advanced Cutaneous Melanoma+8 more
Jonsson Comprehensive Cancer Center 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT04462406
What this trial is testing

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Who this might be right for
Advanced MelanomaClinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8+8 more
ECOG-ACRIN Cancer Research Group 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT03175432
What this trial is testing

Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases

Who this might be right for
BRAF V600 Wild TypeClinical Stage IV Cutaneous Melanoma AJCC v8Intracranial Melanoma+4 more
M.D. Anderson Cancer Center 29
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650986
What this trial is testing

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

Who this might be right for
Advanced Fallopian Tube CarcinomaAdvanced Malignant Solid NeoplasmAdvanced Melanoma+47 more
Roswell Park Cancer Institute 15
Not applicableStudy completedNCT05102773
What this trial is testing

The Effect of the Microbiome on Immune Checkpoint Inhibitor Response in Melanoma Patients

Who this might be right for
Clinical Stage IV Cutaneous Melanoma AJCC v8Pathologic Stage IV Cutaneous Melanoma AJCC v8
Ohio State University Comprehensive Cancer Center 88
Early research (Phase 1)Ended earlyNCT03865212
What this trial is testing

Modified Virus VSV-IFNbetaTYRP1 in Treating Patients With Stage III-IV Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Metastatic Choroid Melanoma+10 more
Mayo Clinic 12
Early research (Phase 1)Ended earlyNCT03727789
What this trial is testing

CBL0137 in Treating Patients With Advanced Extremity Melanoma or Sarcoma

Who this might be right for
Advanced Cutaneous Melanoma of the ExtremityAdvanced Sarcoma of the ExtremityClinical Stage III Cutaneous Melanoma AJCC v8+10 more
Roswell Park Cancer Institute 7
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