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Results for “Patients With Leptomeningeal Disease”

94 trials

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Showing 20 of 94 results

Testing effectiveness (Phase 2)Ended earlyNCT03091478
What this trial is testing

Pembrolizumab in Patients With Leptomeningeal Disease

Who this might be right for
Patients With Leptomeningeal Disease
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 13
Testing effectiveness (Phase 2)UnknownNCT01818713
What this trial is testing

Clinical and Pharmacological Study With 2B3-101 in Patients With Breast Cancer and Leptomeningeal Metastases

Who this might be right for
Meningeal Carcinomatosis
The Netherlands Cancer Institute 6
Not applicableUnknownNCT00938756
What this trial is testing

Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meningeal Syndrome

Who this might be right for
Brain and Central Nervous System TumorsBreast CancerMetastatic Cancer
Centre Oscar Lambret 80
Early research (Phase 1)Active Not RecruitingNCT03025256
What this trial is testing

Intravenous and Intrathecal Nivolumab in Treating Patients With Leptomeningeal Disease

Who this might be right for
Acral Lentiginous MelanomaCentral Nervous System MelanomaClinical Stage IV Cutaneous Melanoma AJCC v8+7 more
M.D. Anderson Cancer Center 71
Testing effectiveness (Phase 2)Study completedNCT04233021
What this trial is testing

Study of Osimertinib in Patients with a Lung Cancer with Brain or Leptomeningeal Metastases with EGFR Mutation

Who this might be right for
Non Small Cell Lung Cancer MetastaticLeptomeningeal MetastasisBrain Metastases+1 more
Intergroupe Francophone de Cancerologie Thoracique 57
Early research (Phase 1)Ended earlyNCT00112619
What this trial is testing

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsCarcinoma of Unknown PrimaryLeukemia+2 more
Pediatric Brain Tumor Consortium 19
Early research (Phase 1)Ended earlyNCT03711422
What this trial is testing

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal DiseaseCentral Nervous System Metastases
National Cancer Centre, Singapore 2
Early research (Phase 1)Active Not RecruitingNCT04661384
What this trial is testing

Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma

Who this might be right for
EpendymomaGlioblastomaMedulloblastoma+1 more
City of Hope Medical Center 10
Not applicableEnded earlyNCT05414123
What this trial is testing

A Therapy Treatment Response Trial in Patients With Leptomeningeal Metastases ((LM) Using CNSide

Who this might be right for
Leptomeningeal MetastasisLeptomeningeal DiseaseLeptomeningeal Neoplasms+2 more
Biocept, Inc. 40
Testing effectiveness (Phase 2)Study completedNCT00992602
What this trial is testing

Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer

Who this might be right for
Central Nervous System MetastasesLeptomeningeal MetastasesRecurrent Breast Cancer+2 more
University of Washington 3
Early research (Phase 1)Looking for participantsNCT05809752
What this trial is testing

A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV)

Who this might be right for
Leptomeningeal DiseaseTriple Negative Breast CancerHER2-positive Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute 18
Early research (Phase 1)Study completedNCT02423525
What this trial is testing

Safety Study of Afatinib for Brain Cancer

Who this might be right for
Brain Cancer
Santosh Kesari 24
Early research (Phase 1)Ended earlyNCT03661424
What this trial is testing

BATs in Patients With Breast Cancer and Leptomeningeal Metastases

Who this might be right for
Breast Cancer FemaleLeptomeningeal Metastases
University of Virginia 3
Early research (Phase 1)Ended earlyNCT00515788
What this trial is testing

DepoCyt Plus Temozolomide in Patients With Neoplastic Meningitis

Who this might be right for
Neoplastic Meningitis
M.D. Anderson Cancer Center 11
Early research (Phase 1)Active Not RecruitingNCT04460937
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

Who this might be right for
Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+56 more
National Cancer Institute (NCI)
Not applicableNot Yet RecruitingNCT06984523
What this trial is testing

Study of Craniospinal Irradiation With Linac Based Volumetric Modulated Arc Therapy (VMAT) for Patients With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
NYU Langone Health 20
Testing effectiveness (Phase 2)Looking for participantsNCT06901817
What this trial is testing

The Safety and Efficacy of Pemetrexed Combined with Nivolumab Via Intraventricular Injection for the Treatment of Refractory Non-squamous Non-small Cell Lung Cancer with Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastasis
Shanghai Cancer Hospital, China 97
Testing effectiveness (Phase 2)Study completedNCT05146219
What this trial is testing

Study of TY-9591 in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation

Who this might be right for
NSCLCEGFR Activating MutationBrain Metastases+1 more
TYK Medicines, Inc 29
Early research (Phase 1)Study completedNCT00002750
What this trial is testing

Melphalan in Patients With Neoplastic Meningitis

Who this might be right for
Brain and Central Nervous System TumorsExtragonadal Germ Cell TumorLeukemia+2 more
Duke University 6
Not applicableNot Yet RecruitingNCT07005791
What this trial is testing

AI-Based Ultrasound Prediction Model for Intracranial Pressure and Prognosis in Lung Cancer Patients With Leptomeningeal Metastasis: A Dual-Center Study

Who this might be right for
Lung Cancer (NSCLC)Leptomeningeal MetastasisIntracranial Pressure
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 142
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