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Results for “Patients With Leptomeningeal Disease”

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Showing 20 of 0 results

Post-approval studies (Phase 4)Active Not RecruitingNCT06282874
What this trial is testing

Lorlatinib in Patients With ALK-Positive NSCLC With Brain or Leptomeningeal Metastases

Who this might be right for
Carcinoma, Non-Small-Cell LungBrain MetastasesLeptomeningeal Metastasis
Guangdong Association of Clinical Trials 41
Testing effectiveness (Phase 2)Study completedNCT04563871
What this trial is testing

Efficacy and Safety of 80mg Osimertinib in Patients With Non-small Cell Lung Cancer(NSCLC)

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Sehhoon Park 73
Early research (Phase 1)Active Not RecruitingNCT04661384
What this trial is testing

Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma

Who this might be right for
EpendymomaGlioblastomaMedulloblastoma+1 more
City of Hope Medical Center 10
Not applicableStudy completedNCT02071056
What this trial is testing

Circulating Tumor DNA in Cerebrospinal Fluid as an Early Biomarker of Leptomeningeal Metastasis (LM)

Who this might be right for
Leptomeningeal Metastasis
Dartmouth-Hitchcock Medical Center 5
Early research (Phase 1)Looking for participantsNCT07361705
What this trial is testing

Zorifertinib With Osimertinib for NSCLC With Meningeal Progression

Who this might be right for
Patients With Advanced Non-small Cell Lung Cancer With Meningeal Progression After Osimertinib Treatment
Alpha Biopharma (Jiangsu) Co., Ltd. 42
Early research (Phase 1)Ended earlyNCT00512460
What this trial is testing

RTA 744 Injection in Patients With Leptomeningeal Disease

Who this might be right for
Neoplastic MeningitisSolid TumorLymphoma+2 more
M.D. Anderson Cancer Center 7
Testing effectiveness (Phase 2)Study completedNCT02336451
What this trial is testing

A Phase II Study to Evaluate the Efficacy and Safety of Oral Ceritinib in Patients With ALK-positive NSCLC Metastatic to the Brain and/or to Leptomeninges

Who this might be right for
ALK-positive Non-small Cell Lung Cancer
Novartis Pharmaceuticals 156
Testing effectiveness (Phase 2)Active Not RecruitingNCT00338377
What this trial is testing

Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma

Who this might be right for
Melanoma
M.D. Anderson Cancer Center 1,230
Early research (Phase 1)Study completedNCT02228369
What this trial is testing

Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors, AZD3759 or AZD9291, in Patients Who Have Advanced Non-Small Cell Lung Cancer

Who this might be right for
EGFR Mutation Positive Advanced Non Small Cell Lung Cancer
AstraZeneca 108
Early research (Phase 1)Ended earlyNCT00527410
What this trial is testing

A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis

Who this might be right for
Leptomeningeal Carcinomatosis
Biogen 9
Not applicableNot Yet RecruitingNCT07659652
What this trial is testing

Quality of Life for Patients With Breast Cancer Brain Metastases and Leptomeningeal Disease

Who this might be right for
Breast Cancer, Quality of LifeBreast Cancer, MetastaticBreast Cancer, Metastatic Breast Cancer+2 more
University of California, San Francisco 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07751744
What this trial is testing

Phase 1/2 Study Evaluating the Safety, PK/PD, and Clinical Activity of Oral JBI-778 in Patients With Brain Metastases, Leptomeningeal Disease, or Recurrent High Grade Glioma

Who this might be right for
Brain Metastases From Solid TumorsLeptomeningeal DiseaseHigh Grade Glioma (HGG)+1 more
Jubilant Therapeutics Inc. 113
Testing effectiveness (Phase 2)Study completedNCT00450866
What this trial is testing

Epothilone B in Treating Patients With CNS Metastases From Breast Cancer

Who this might be right for
Breast CancerMetastatic Cancer
David Peereboom, MD 55
Early research (Phase 1)Ended earlyNCT03711422
What this trial is testing

Afatinib on CNS Metastases and LMD in EGFR Mutation Positive NSCLC

Who this might be right for
Non-small Cell Lung CancerLeptomeningeal DiseaseCentral Nervous System Metastases
National Cancer Centre, Singapore 2
Early research (Phase 1)Active Not RecruitingNCT05598853
What this trial is testing

Intrathecal Double Checkpoint Inhibition

Who this might be right for
Leptomeningeal MetastasisNon-small Cell Lung Cancer Stage IVMelanoma Stage IV
University of Zurich 26
Not applicableLooking for participantsNCT06638294
What this trial is testing

Study in Patients With Breast Cancer Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis of Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 30
Not applicableActive Not RecruitingNCT05793489
What this trial is testing

Prospective Double Arm Randomized Trial: WBRT Alone and WBRT Plus Silibinin

Who this might be right for
Brain Metastases, Adult
Istituto Clinico Humanitas 44
Very early researchStudy completedNCT00424242
What this trial is testing

Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Northwestern University 15
Not applicableNot Yet RecruitingNCT07689721
What this trial is testing

CtDNA-Guided Intraventricular Therapy for CNS Malignancies

Who this might be right for
Leptomeningeal DiseaseGlioblastomaBrain Metastases+2 more
Alireza Mansouri 77
Not applicableLooking for participantsNCT06417710
What this trial is testing

Standardized Clinical Assessment of Patients With Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisLeptomeningeal DiseaseLeptomeningeal Neoplasms+1 more
University of Zurich 200
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