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Results for “Pediatric Glioblastoma Multiforme”

55 trials

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Showing 20 of 55 results

Testing effectiveness (Phase 2)Ended earlyNCT03330197
What this trial is testing

Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

Who this might be right for
Pediatric Brain TumorDiffuse Intrinsic Pontine Glioma
Alaunos Therapeutics 6
Early research (Phase 1)Study completedNCT02457845
What this trial is testing

HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors

Who this might be right for
Supratentorial Neoplasms, MalignantMalignant GliomaGlioblastoma+4 more
Gregory K. Friedman, MD 13
Early research (Phase 1)Looking for participantsNCT06894979
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Who this might be right for
Childhood AstrocytomaChildhood Diffuse Intrinsic Pontine GliomaChildhood Diffuse Midline Glioma+2 more
Children's Oncology Group 54
Early research (Phase 1)Study completedNCT02323880
What this trial is testing

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Who this might be right for
Malignant GliomaRecurrent Brain NeoplasmRecurrent Childhood Central Nervous System Neoplasm+7 more
Children's Oncology Group 59
Testing effectiveness (Phase 2)Ended earlyNCT02372409
What this trial is testing

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

Who this might be right for
GliomaPilocytic AstrocytomaAnaplastic Astrocytoma+6 more
Washington University School of Medicine 6
Early research (Phase 1)Study completedNCT00634231
What this trial is testing

A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors

Who this might be right for
Malignant GliomaRecurrent Ependymoma
Candel Therapeutics, Inc. 8
Testing effectiveness (Phase 2)Ended earlyNCT02758366
What this trial is testing

Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma

Who this might be right for
Glioblastoma (GBM)DIPGBrainstem Glioma, Pediatric+5 more
Meyer Children's Hospital IRCCS 21
Early research (Phase 1)Looking for participantsNCT04573140
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)

Who this might be right for
Adult GlioblastomaHigh Grade GliomaWHO Grade III or IV Malignant Glioma
University of Florida 28
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT04049669
What this trial is testing

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Who this might be right for
GlioblastomaMedulloblastomaEpendymoma+1 more
Theodore S. Johnson 130
Testing effectiveness (Phase 2)Study completedNCT02684058
What this trial is testing

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Who this might be right for
Diffuse AstrocytomaAnaplastic AstrocytomaAstrocytoma+19 more
Novartis Pharmaceuticals 151
Testing effectiveness (Phase 2)Looking for participantsNCT04094610
What this trial is testing

Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

Who this might be right for
Locally Advanced Solid TumorsMetastatic Solid TumorsLymphoma+1 more
Turning Point Therapeutics, Inc. 75
Early research (Phase 1)Looking for participantsNCT05835687
What this trial is testing

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

Who this might be right for
Central Nervous System NeoplasmsAtypical Teratoid/Rhabdoid TumorDiffuse Midline Glioma, H3 K27M-Mutant+4 more
St. Jude Children's Research Hospital 48
Early research (Phase 1)UnknownNCT00314925
What this trial is testing

Safety Study of Seneca Valley Virus in Patients With Solid Tumors With Neuroendocrine Features

Who this might be right for
CarcinoidNeuroendocrine
Neotropix 60
Early research (Phase 1)Looking for participantsNCT07492316
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB)

Who this might be right for
Recurrent Medulloblastoma
University of Florida 24
Early research (Phase 1)Not Yet RecruitingNCT06946680
What this trial is testing

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)

Who this might be right for
High-grade GliomaDiffuse Intrinsic Pontine Glioma
University of Florida 24
Early research (Phase 1)Study completedNCT03434262
What this trial is testing

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Ganglioglioma+53 more
St. Jude Children's Research Hospital 68
Testing effectiveness (Phase 2)Study completedNCT00095940
What this trial is testing

Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors

Who this might be right for
Recurrent Childhood Anaplastic AstrocytomaRecurrent Childhood Brain Stem GliomaRecurrent Childhood Ependymoma+5 more
National Cancer Institute (NCI) 52
Early research (Phase 1)Study completedNCT01808820
What this trial is testing

Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma

Who this might be right for
Malignant GliomaGlioblastoma MultiformeAnaplastic Astrocytoma+1 more
Macarena De La Fuente, MD 20
Not applicableLooking for participantsNCT04188535
What this trial is testing

Serial MRI Scans During Radiation Therapy

Who this might be right for
GlioblastomaEsophageal CancerRadiotherapy+5 more
Dana-Farber Cancer Institute 149
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