Large-scale testing (Phase 3)Ended earlyNCT04218084What this trial is testingStudy to Evaluate the Effect of GBT440 on TCD in Pediatrics With Sickle Cell DiseaseWho this might be right forSickle Cell Disease Pfizer 236
Large-scale testing (Phase 3)Study completedNCT02720536What this trial is testingExtended Evaluation of Deferasirox Film-coated Tablet (FCT) FormulationWho this might be right forChronic Iron Overload Novartis Pharmaceuticals 53
Post-approval studies (Phase 4)Study completedNCT00867932What this trial is testingEculizumab Pharmacokinetics/Pharmacodynamics Study in Pediatric/Adolescent Paroxysmal Nocturnal Hemoglobinuria (PNH)Who this might be right forHemoglobinuria, Paroxysmal Alexion Pharmaceuticals, Inc. 7
Not applicableStudy completedNCT04917783What this trial is testingHealth Literacy - Neurocognitive Screening in Pediatric SCDWho this might be right forSickle Cell Disease Medical College of Wisconsin 46
Large-scale testing (Phase 3)Ended earlyNCT03615924What this trial is testingEffect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease AstraZeneca 193
Testing effectiveness (Phase 2)Study completedNCT01193348What this trial is testingAn Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic SyndromeWho this might be right forAtypical Hemolytic-Uremic Syndrome Alexion Pharmaceuticals, Inc. 22
Post-approval studies (Phase 4)Not Yet RecruitingNCT07682662What this trial is testingLow Dose Bolus Ketamine For Use In Sickle Cell Pain CrisisWho this might be right forVaso-Occlusive Pain Episode in Sickle Cell DiseaseSickle Cell Disease (SCD) University of Mississippi Medical Center 400
Not applicableStudy completedNCT04388241What this trial is testingPreliminary Feasibility and Efficacy of Behavioral Intervention to Reduce Pain-Related Disability in Pediatric SCDWho this might be right forSickle Cell DiseasePain Children's National Research Institute 22
Not applicableStudy completedNCT07094646What this trial is testingFull Assessment of Clinical Transfusion SupportWho this might be right forSickle Cell AnemiaBlood TransfusionMalaria Parasitaemia Children's Hospital Medical Center, Cincinnati 250
Not applicableLooking for participantsNCT06691867What this trial is testingIntegrative Training Program for Pediatric Sickle Cell PainWho this might be right forSickle Cell Disease Emory University 155
Large-scale testing (Phase 3)Looking for participantsNCT06449001What this trial is testingStudy of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular HemolysisWho this might be right forParoxysmal Nocturnal HemoglobinuriaPNHExtravascular Hemolysis Alexion Pharmaceuticals, Inc. 6
Testing effectiveness (Phase 2)Study completedNCT03296345What this trial is testingAdjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive CrisisWho this might be right forSickle Cell DiseaseVaso-Occlusive Crisis UCSF Benioff Children's Hospital Oakland 62
Not applicableStudy completedNCT01959958What this trial is testingEvaluation of Nocturnal Enuresis and Barriers to Treatment Among Pediatric Patients With Sickle Cell DiseaseWho this might be right forSickle Cell Disease St. Jude Children's Research Hospital 250
Not applicableStudy completedNCT04676113What this trial is testingObesity in Pediatric Sickle Cell Disease: A New PhenomenonWho this might be right forSickle Cell DiseaseObesity, ChildhoodHypertension+2 more University of Mississippi Medical Center 100
Large-scale testing (Phase 3)Active Not RecruitingNCT04958265What this trial is testingA Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS)Who this might be right forAtypical Hemolytic Uremic Syndrome Hoffmann-La Roche 41
Early research (Phase 1)Study completedNCT01506544What this trial is testingPharmacokinetics (PK) of Liquid Hydroxyurea in Pediatric Patients With Sickle Cell AnemiaWho this might be right forSickle Cell Anemia Children's Mercy Hospital Kansas City 39
Large-scale testing (Phase 3)Study completedNCT01197417What this trial is testingIntravenous Magnesium for Sickle Cell Vasoocclusive CrisisWho this might be right forSickle Cell Disease Medical College of Wisconsin 208
Not applicableEnded earlyNCT02887118What this trial is testingDense Red Blood Cells in Sickle Cell ChildrenWho this might be right forSickle Cell Disease Centre Hospitalier Intercommunal Creteil 82
Testing effectiveness (Phase 2)Looking for participantsNCT05953584What this trial is testingOpen-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary StrokeWho this might be right forSickle Cell Disease Forma Therapeutics, Inc. 27
Not applicableLooking for participantsNCT06773715What this trial is testingVirtual Reality As Adjunct Therapy for Vaso-Occlusive PainWho this might be right forSickle Cell DiseaseVaso-occlusive Pain Episodes Louisiana State University Health Sciences Center in New Orleans 36