Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Pediatric High Risk Gliomas”

86 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 86 results

Early research (Phase 1)Study completedNCT00036959
What this trial is testing

ABT-751 in Treating Young Patients With Refractory Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+6 more
National Institutes of Health Clinical Center (CC) 90
Testing effectiveness (Phase 2)Ended earlyNCT03690869
What this trial is testing

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Who this might be right for
Relapsed Solid TumorRefractory Solid TumorRelapsed Central Nervous System Tumor+3 more
Regeneron Pharmaceuticals 57
Testing effectiveness (Phase 2)Study completedNCT03257631
What this trial is testing

Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

Who this might be right for
Central Nervous System NeoplasmsMedulloblastoma
Celgene 53
Early research (Phase 1)Study completedNCT00363272
What this trial is testing

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Study completedNCT00004212
What this trial is testing

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

Who this might be right for
Brain and Central Nervous System TumorsLymphomaUnspecified Childhood Solid Tumor, Protocol Specific
Daiichi Sankyo
Early research (Phase 1)Looking for participantsNCT06894979
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Who this might be right for
Childhood AstrocytomaChildhood Diffuse Intrinsic Pontine GliomaChildhood Diffuse Midline Glioma+2 more
Children's Oncology Group 54
Early research (Phase 1)Active Not RecruitingNCT03478462
What this trial is testing

Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma

Who this might be right for
Pediatric Solid TumorPediatric LymphomaPediatric Brain Tumor+5 more
Cellectar Biosciences, Inc. 30
Not applicableWithdrawnNCT03577600
What this trial is testing

Compassionate Treatment in Children With Brain Tumors With the Cytotron®

Who this might be right for
Pediatric Brain Tumor
Hospital Infantil de Mexico Federico Gomez
Early research (Phase 1)Ended earlyNCT05429502
What this trial is testing

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Who this might be right for
Neuroblastoma
Novartis Pharmaceuticals 12
Early research (Phase 1)Active Not RecruitingNCT05610891
What this trial is testing

Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG

Who this might be right for
High-Grade Glioma
Cellectar Biosciences, Inc. 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT00840047
What this trial is testing

Methionine PET/CT Studies In Patients With Cancer

Who this might be right for
Brain Tumors and/or Solid Tumors IncludingBrain Stem GliomaHigh Grade CNS Tumors+11 more
St. Jude Children's Research Hospital 503
Early research (Phase 1)Looking for participantsNCT05835687
What this trial is testing

Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors

Who this might be right for
Central Nervous System NeoplasmsAtypical Teratoid/Rhabdoid TumorDiffuse Midline Glioma, H3 K27M-Mutant+4 more
St. Jude Children's Research Hospital 48
Early research (Phase 1)Ended earlyNCT02722512
What this trial is testing

Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine

Who this might be right for
Glioblastoma MultiformeAstrocytoma, Grade IIIAnaplastic Ependymoma+2 more
Ann & Robert H Lurie Children's Hospital of Chicago 10
Not applicableLooking for participantsNCT05839379
What this trial is testing

Targeted Pediatric High-Grade Glioma Therapy

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 350
Testing effectiveness (Phase 2)Study completedNCT01553149
What this trial is testing

Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma

Who this might be right for
Neurofibromatosis Type 1Recurrent Childhood Pilocytic AstrocytomaRecurrent Childhood Visual Pathway Glioma
National Cancer Institute (NCI) 75
Testing effectiveness (Phase 2)Looking for participantsNCT05660408
What this trial is testing

RNA Lipid Particles Targeting Pediatric Recurrent Intracranial Malignancies and Other systEmic Solid Tumors

Who this might be right for
Recurrent Pulmonary OsteosarcomaRecurrent High-grade Glioma
University of Florida 36
Early research (Phase 1)Study completedNCT01644773
What this trial is testing

Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)

Who this might be right for
Diffuse Intrinsic Pontine GliomaHigh-grade Glioma
St. Jude Children's Research Hospital 36
Testing effectiveness (Phase 2)Ended earlyNCT03330197
What this trial is testing

Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

Who this might be right for
Pediatric Brain TumorDiffuse Intrinsic Pontine Glioma
Alaunos Therapeutics 6
Early research (Phase 1)Study completedNCT00005796
What this trial is testing

Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors

Who this might be right for
Bone Marrow SuppressionBrain and Central Nervous System TumorsDrug/Agent Toxicity by Tissue/Organ
Indiana University 10
Testing effectiveness (Phase 2)Study completedNCT01837862
What this trial is testing

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Who this might be right for
Pilomyxoid AstrocytomaPilocytic AstrocytomaGlioma, Astrocytic+9 more
Julie Krystal 36
Load More Results