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Results for “Pediatric High Risk Gliomas”

90 trials

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Showing 20 of 90 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06521567
What this trial is testing

Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Who this might be right for
MelanomaHodgkin LymphomaHigh and Low Grade Glioma+9 more
GlaxoSmithKline 83
Testing effectiveness (Phase 2)Ended earlyNCT02332889
What this trial is testing

Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs

Who this might be right for
GliomasMedulloblastomaNeuroectodermal Tumors, Primitive
University of Louisville 1
Very early researchStudy completedNCT03250520
What this trial is testing

Application of Palliative Treatment in Children With Brain Stem Glioma and Recurrent High-grade Tumors in the Central Nervous System With the Nanomaterial NPt-Ca

Who this might be right for
Brain Tumor, Pediatric, Brainstem GliomaBrain Tumor, Pediatric, Recurrent
Hospital Infantil de Mexico Federico Gomez 8
Early research (Phase 1)Looking for participantsNCT07492316
What this trial is testing

RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB)

Who this might be right for
Recurrent Medulloblastoma
University of Florida 24
Testing effectiveness (Phase 2)Study completedNCT01574092
What this trial is testing

Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas

Who this might be right for
Pediatric High Risk Gliomas
Hospital Sant Joan de Deu 39
Testing effectiveness (Phase 2)Study completedNCT03245151
What this trial is testing

Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors

Who this might be right for
Recurrent and Refractory Solid Tumors
Eisai Inc. 64
Early research (Phase 1)Not Yet RecruitingNCT06946680
What this trial is testing

IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Newly Diagnosed and Recurrent Pediatric High-grade Glioma (pHGG) and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (ndDIPG)

Who this might be right for
High-grade GliomaDiffuse Intrinsic Pontine Glioma
University of Florida 24
Early research (Phase 1)Active Not RecruitingNCT04978727
What this trial is testing

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Who this might be right for
MedulloblastomaGlioblastoma MultiformeAnaplastic Astrocytoma+5 more
Children's Oncology Group 35
Testing effectiveness (Phase 2)Study completedNCT02343406
What this trial is testing

Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade Gliomas

Who this might be right for
Glioblastoma
AbbVie 266
Testing effectiveness (Phase 2)Ended earlyNCT02758366
What this trial is testing

Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma

Who this might be right for
Glioblastoma (GBM)DIPGBrainstem Glioma, Pediatric+5 more
Meyer Children's Hospital IRCCS 21
Early research (Phase 1)Ended earlyNCT05429502
What this trial is testing

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

Who this might be right for
Neuroblastoma
Novartis Pharmaceuticals 12
Early research (Phase 1)Study completedNCT00303940
What this trial is testing

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorKidney Cancer+5 more
National Institutes of Health Clinical Center (CC) 26
Testing effectiveness (Phase 2)Ended earlyNCT03690869
What this trial is testing

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Who this might be right for
Relapsed Solid TumorRefractory Solid TumorRelapsed Central Nervous System Tumor+3 more
Regeneron Pharmaceuticals 57
Early research (Phase 1)WithdrawnNCT05082493
What this trial is testing

A Multicenter, Study of the Safety and Pharmacokinetics of Intravenously Infused Berubicin in Pediatric Patients With Progressive, Refractory, or Recurrent High Grade Gliomas

Who this might be right for
High Grade Glioma
WPD Pharmaceuticals Sp. z o.o.
Early research (Phase 1)Looking for participantsNCT05298995
What this trial is testing

GD2-CAR T Cells for Pediatric Brain Tumours

Who this might be right for
Brain Tumor, PediatricMedulloblastoma, ChildhoodEmbryonal Tumor+4 more
Bambino Gesù Hospital and Research Institute 54
Testing effectiveness (Phase 2)Looking for participantsNCT06712875
What this trial is testing

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

Who this might be right for
Low Grade GliomaHigh Grade Glioma
Ann & Robert H Lurie Children's Hospital of Chicago 27
Early research (Phase 1)Study completedNCT03128047
What this trial is testing

HUMC 1612: Optune NovoTTF-200A System

Who this might be right for
High Grade GliomaEpendymoma
Hackensack Meridian Health 7
Testing effectiveness (Phase 2)Study completedNCT04911621
What this trial is testing

Adjuvant Dendritic Cell Immunotherapy for Pediatric Patients With High-grade Glioma or Diffuse Intrinsic Pontine Glioma

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine Glioma
University Hospital, Antwerp 10
Early research (Phase 1)Ended earlyNCT00880061
What this trial is testing

An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma

Who this might be right for
Brain NeoplasmGlioma
National Institute of Neurological Disorders and Stroke (NINDS) 7
Early research (Phase 1)Study completedNCT00006024
What this trial is testing

Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma

Who this might be right for
Brain TumorCentral Nervous System Tumor
Children's Oncology Group 32
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