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Results for “Pediatric Low-grade Glioma”

41 trials

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Showing 20 of 41 results

Testing effectiveness (Phase 2)Looking for participantsNCT05180825
What this trial is testing

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy

Who this might be right for
Grade 1 GliomaMixed Glio-neuronal TumorsPleomorphic Xanthoastrocytoma
University Hospital, Strasbourg, France 134
Post-approval studies (Phase 4)Active Not RecruitingNCT03975829
What this trial is testing

Pediatric Long-Term Follow-up and Rollover Study

Who this might be right for
Diffuse AstrocytomaAnaplastic AstrocytomaAstrocytoma+20 more
Novartis Pharmaceuticals 163
Not applicableLooking for participantsNCT03761121
What this trial is testing

Developing Fast Pediatric Imaging

Who this might be right for
Pediatric Low-grade Gliomas
Boston Children's Hospital 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT00840047
What this trial is testing

Methionine PET/CT Studies In Patients With Cancer

Who this might be right for
Brain Tumors and/or Solid Tumors IncludingBrain Stem GliomaHigh Grade CNS Tumors+11 more
St. Jude Children's Research Hospital 503
Early research (Phase 1)Study completedNCT01682746
What this trial is testing

Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors

Who this might be right for
Brain Tumor, Recurrent
Harry T Whelan, MD 5
Testing effectiveness (Phase 2)Looking for participantsNCT04775485
What this trial is testing

Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

Who this might be right for
Low-grade GliomaAdvanced Solid Tumor
Day One Biopharmaceuticals, Inc. 141
Large-scale testing (Phase 3)Not Yet RecruitingNCT07004075
What this trial is testing

FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration

Who this might be right for
Low-grade GliomaPediatric Low-grade GliomaspLGG With BRAF Alteration
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 102
Testing effectiveness (Phase 2)Active Not RecruitingNCT03363217
What this trial is testing

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

Who this might be right for
Low-grade GliomaPlexiform NeurofibromaCentral Nervous System Glioma
St. Justine's Hospital 114
Testing effectiveness (Phase 2)Study completedNCT01288235
What this trial is testing

Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation

Who this might be right for
Brain TumorLow Grade GliomaAstrocytoma+2 more
Massachusetts General Hospital 100
Not applicableStudy completedNCT01346267
What this trial is testing

Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy

Who this might be right for
Central Nervous System Tumor, PediatricChemotherapy-induced Nausea and VomitingUnspecified Childhood Solid Tumor, Protocol Specific
University of South Florida 187
Early research (Phase 1)Study completedNCT00100880
What this trial is testing

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+23 more
National Cancer Institute (NCI) 45
Testing effectiveness (Phase 2)Study completedNCT01734512
What this trial is testing

PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children

Who this might be right for
Pediatric Recurrent Progressive Low-grade GliomasPediatric Progressive Low-grade Gliomas
University of California, San Francisco 65
Testing effectiveness (Phase 2)Study completedNCT00005952
What this trial is testing

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorHead and Neck Cancer+5 more
Duke University 30
Testing effectiveness (Phase 2)Study completedNCT02684058
What this trial is testing

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Who this might be right for
Diffuse AstrocytomaAnaplastic AstrocytomaAstrocytoma+19 more
Novartis Pharmaceuticals 151
Testing effectiveness (Phase 2)Study completedNCT01837862
What this trial is testing

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Who this might be right for
Pilomyxoid AstrocytomaPilocytic AstrocytomaGlioma, Astrocytic+9 more
Julie Krystal 36
Testing effectiveness (Phase 2)WithdrawnNCT05222165
What this trial is testing

Study With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 Alterations

Who this might be right for
Advanced Solid TumorCNS TumorRecurrent WHO Grade II Glioma
Helsinn Healthcare SA
Testing effectiveness (Phase 2)UnknownNCT00005084
What this trial is testing

Magnetic Resonance Imaging in Treating Children With Progressive Low-Grade Astrocytoma

Who this might be right for
Brain and Central Nervous System Tumors
Jonsson Comprehensive Cancer Center 24
Testing effectiveness (Phase 2)Looking for participantsNCT06666348
What this trial is testing

Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK

Who this might be right for
Pediatric Low-grade Glioma
St. Justine's Hospital 50
Testing effectiveness (Phase 2)Looking for participantsNCT06712875
What this trial is testing

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

Who this might be right for
Low Grade GliomaHigh Grade Glioma
Ann & Robert H Lurie Children's Hospital of Chicago 27
Early research (Phase 1)Study completedNCT00363272
What this trial is testing

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
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