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Results for “Pediatric Low-grade Glioma”

43 trials

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Showing 20 of 43 results

Testing effectiveness (Phase 2)Looking for participantsNCT06666348
What this trial is testing

Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK

Who this might be right for
Pediatric Low-grade Glioma
St. Justine's Hospital 50
Testing effectiveness (Phase 2)UnknownNCT00005084
What this trial is testing

Magnetic Resonance Imaging in Treating Children With Progressive Low-Grade Astrocytoma

Who this might be right for
Brain and Central Nervous System Tumors
Jonsson Comprehensive Cancer Center 24
Not applicableLooking for participantsNCT07506239
What this trial is testing

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

Who this might be right for
Low-grade GliomaRecurrent Low Grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco 40
Large-scale testing (Phase 3)Active Not RecruitingNCT05566795
What this trial is testing

DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

Who this might be right for
Low-grade GliomaRapidly Accelerated Fibrosarcoma (RAF) Altered GliomaPediatric Low-grade Glioma
Day One Biopharmaceuticals, Inc. 418
Testing effectiveness (Phase 2)Active Not RecruitingNCT06521567
What this trial is testing

Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Who this might be right for
MelanomaHodgkin LymphomaHigh and Low Grade Glioma+9 more
GlaxoSmithKline 83
Early research (Phase 1)Study completedNCT00363272
What this trial is testing

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Early research (Phase 1)Active Not RecruitingNCT06104488
What this trial is testing

Avutometinib for People With Solid Tumor Cancers

Who this might be right for
Refractory CancerCNS TumorsCNS Tumor, Adult+12 more
Memorial Sloan Kettering Cancer Center 3
Testing effectiveness (Phase 2)Study completedNCT04659421
What this trial is testing

Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas

Who this might be right for
Low-grade GliomaPediatric Brain Tumor
Beijing Sanbo Brain Hospital 60
Not applicableStudy completedNCT01346267
What this trial is testing

Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy

Who this might be right for
Central Nervous System Tumor, PediatricChemotherapy-induced Nausea and VomitingUnspecified Childhood Solid Tumor, Protocol Specific
University of South Florida 187
Not applicableLooking for participantsNCT03761121
What this trial is testing

Developing Fast Pediatric Imaging

Who this might be right for
Pediatric Low-grade Gliomas
Boston Children's Hospital 300
Testing effectiveness (Phase 2)Looking for participantsNCT05180825
What this trial is testing

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy

Who this might be right for
Grade 1 GliomaMixed Glio-neuronal TumorsPleomorphic Xanthoastrocytoma
University Hospital, Strasbourg, France 134
Testing effectiveness (Phase 2)Ended earlyNCT00788125
What this trial is testing

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
City of Hope Medical Center 7
Testing effectiveness (Phase 2)Study completedNCT01497860
What this trial is testing

Vinorelbine for Children With Progressive or Recurrent Low-grade Gliomas

Who this might be right for
Low-grade Glioma
Eugene Hwang 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT01089101
What this trial is testing

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

Who this might be right for
Low Grade GliomaRecurrent Childhood Pilocytic AstrocytomaRecurrent Neurofibromatosis Type 1+3 more
National Cancer Institute (NCI) 217
Testing effectiveness (Phase 2)Study completedNCT03213665
What this trial is testing

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Hodgkin LymphomaAnn Arbor Stage III Non-Hodgkin Lymphoma+38 more
National Cancer Institute (NCI) 20
Early research (Phase 1)Study completedNCT00052780
What this trial is testing

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+22 more
National Cancer Institute (NCI) 72
Large-scale testing (Phase 3)Not Yet RecruitingNCT07004075
What this trial is testing

FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration

Who this might be right for
Low-grade GliomaPediatric Low-grade GliomaspLGG With BRAF Alteration
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 102
Testing effectiveness (Phase 2)Looking for participantsNCT04775485
What this trial is testing

Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

Who this might be right for
Low-grade GliomaAdvanced Solid Tumor
Day One Biopharmaceuticals, Inc. 141
Testing effectiveness (Phase 2)Active Not RecruitingNCT03363217
What this trial is testing

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

Who this might be right for
Low-grade GliomaPlexiform NeurofibromaCentral Nervous System Glioma
St. Justine's Hospital 114
Testing effectiveness (Phase 2)Study completedNCT01734512
What this trial is testing

PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children

Who this might be right for
Pediatric Recurrent Progressive Low-grade GliomasPediatric Progressive Low-grade Gliomas
University of California, San Francisco 65
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