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Results for “Pediatric Low-grade Gliomas”

41 trials

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Showing 20 of 41 results

Early research (Phase 1)Study completedNCT00363272
What this trial is testing

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

Who this might be right for
Childhood Burkitt LymphomaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Large-scale testing (Phase 3)Not Yet RecruitingNCT07004075
What this trial is testing

FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration

Who this might be right for
Low-grade GliomaPediatric Low-grade GliomaspLGG With BRAF Alteration
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 102
Testing effectiveness (Phase 2)Looking for participantsNCT05180825
What this trial is testing

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy

Who this might be right for
Grade 1 GliomaMixed Glio-neuronal TumorsPleomorphic Xanthoastrocytoma
University Hospital, Strasbourg, France 134
Testing effectiveness (Phase 2)Active Not RecruitingNCT03363217
What this trial is testing

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

Who this might be right for
Low-grade GliomaPlexiform NeurofibromaCentral Nervous System Glioma
St. Justine's Hospital 114
Testing effectiveness (Phase 2)Active Not RecruitingNCT00840047
What this trial is testing

Methionine PET/CT Studies In Patients With Cancer

Who this might be right for
Brain Tumors and/or Solid Tumors IncludingBrain Stem GliomaHigh Grade CNS Tumors+11 more
St. Jude Children's Research Hospital 503
Testing effectiveness (Phase 2)Study completedNCT01188096
What this trial is testing

A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas

Who this might be right for
Brain Tumors
Wake Forest University Health Sciences 23
Early research (Phase 1)Study completedNCT01682746
What this trial is testing

Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors

Who this might be right for
Brain Tumor, Recurrent
Harry T Whelan, MD 5
Testing effectiveness (Phase 2)Study completedNCT01837862
What this trial is testing

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Who this might be right for
Pilomyxoid AstrocytomaPilocytic AstrocytomaGlioma, Astrocytic+9 more
Julie Krystal 36
Testing effectiveness (Phase 2)Looking for participantsNCT06712875
What this trial is testing

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

Who this might be right for
Low Grade GliomaHigh Grade Glioma
Ann & Robert H Lurie Children's Hospital of Chicago 27
Very early researchLooking for participantsNCT06381570
What this trial is testing

Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas

Who this might be right for
Low-grade Glioma
Daniel Morgenstern 57
Early research (Phase 1)Looking for participantsNCT06104488
What this trial is testing

Avutometinib for People With Solid Tumor Cancers

Who this might be right for
Refractory CancerCNS TumorsCNS Tumor, Adult+12 more
Memorial Sloan Kettering Cancer Center 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT01089101
What this trial is testing

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

Who this might be right for
Low Grade GliomaRecurrent Childhood Pilocytic AstrocytomaRecurrent Neurofibromatosis Type 1+3 more
National Cancer Institute (NCI) 220
Early research (Phase 1)Study completedNCT00100880
What this trial is testing

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+23 more
National Cancer Institute (NCI) 45
Testing effectiveness (Phase 2)UnknownNCT00005084
What this trial is testing

Magnetic Resonance Imaging in Treating Children With Progressive Low-Grade Astrocytoma

Who this might be right for
Brain and Central Nervous System Tumors
Jonsson Comprehensive Cancer Center 24
Testing effectiveness (Phase 2)Ended earlyNCT00788125
What this trial is testing

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorExtragonadal Germ Cell Tumor+8 more
City of Hope Medical Center 7
Not applicableStudy completedNCT01346267
What this trial is testing

Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy

Who this might be right for
Central Nervous System Tumor, PediatricChemotherapy-induced Nausea and VomitingUnspecified Childhood Solid Tumor, Protocol Specific
University of South Florida 187
Early research (Phase 1)Study completedNCT01130077
What this trial is testing

A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas

Who this might be right for
Newly Diagnosed Pediatric Pontine GliomaNewly Diagnosed Pediatric High Grade GliomaRecurrent Pediatric High Grade Glioma+1 more
James Felker 60
Not applicableTemporarily pausedNCT05934630
What this trial is testing

Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors

Who this might be right for
Anaplastic AstrocytomaDiffuse Brainstem GliomaGlioblastoma Multiforme+15 more
Pediatric Brain Tumor Consortium 300
Large-scale testing (Phase 3)Looking for participantsNCT05566795
What this trial is testing

DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

Who this might be right for
Low-grade GliomaRapidly Accelerated Fibrosarcoma (RAF) Altered GliomaPediatric Low-grade Glioma
Day One Biopharmaceuticals, Inc. 400
Testing effectiveness (Phase 2)Study completedNCT03233204
What this trial is testing

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+33 more
National Cancer Institute (NCI) 6
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