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Results for “Pediatric Low-grade Gliomas”

42 trials

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Showing 20 of 42 results

Testing effectiveness (Phase 2)Study completedNCT03194906
What this trial is testing

Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors

Who this might be right for
Glioma of BrainCraniopharyngiomaEpendymoma+1 more
St. Jude Children's Research Hospital 34
Not applicableLooking for participantsNCT03761121
What this trial is testing

Developing Fast Pediatric Imaging

Who this might be right for
Pediatric Low-grade Gliomas
Boston Children's Hospital 300
Early research (Phase 1)Study completedNCT00053963
What this trial is testing

FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+22 more
National Cancer Institute (NCI) 30
Not applicableLooking for participantsNCT07506239
What this trial is testing

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

Who this might be right for
Low-grade GliomaRecurrent Low Grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco 40
Early research (Phase 1)Study completedNCT00052780
What this trial is testing

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+22 more
National Cancer Institute (NCI) 72
Testing effectiveness (Phase 2)Study completedNCT01188096
What this trial is testing

A Trial of Poly-ICLC in the Management of Recurrent Pediatric Low Grade Gliomas

Who this might be right for
Brain Tumors
Wake Forest University Health Sciences 23
Testing effectiveness (Phase 2)Study completedNCT00005952
What this trial is testing

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorHead and Neck Cancer+5 more
Duke University 30
Testing effectiveness (Phase 2)Study completedNCT03213665
What this trial is testing

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Hodgkin LymphomaAnn Arbor Stage III Non-Hodgkin Lymphoma+38 more
National Cancer Institute (NCI) 20
Testing effectiveness (Phase 2)Study completedNCT01837862
What this trial is testing

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Who this might be right for
Pilomyxoid AstrocytomaPilocytic AstrocytomaGlioma, Astrocytic+9 more
Julie Krystal 36
Not applicableStudy completedNCT01346267
What this trial is testing

Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy

Who this might be right for
Central Nervous System Tumor, PediatricChemotherapy-induced Nausea and VomitingUnspecified Childhood Solid Tumor, Protocol Specific
University of South Florida 187
Testing effectiveness (Phase 2)Active Not RecruitingNCT06521567
What this trial is testing

Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Who this might be right for
MelanomaHodgkin LymphomaHigh and Low Grade Glioma+9 more
GlaxoSmithKline 83
Testing effectiveness (Phase 2)Looking for participantsNCT06712875
What this trial is testing

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

Who this might be right for
Low Grade GliomaHigh Grade Glioma
Ann & Robert H Lurie Children's Hospital of Chicago 27
Early research (Phase 1)Study completedNCT00303940
What this trial is testing

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorKidney Cancer+5 more
National Institutes of Health Clinical Center (CC) 26
Testing effectiveness (Phase 2)Study completedNCT02684058
What this trial is testing

Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors

Who this might be right for
Diffuse AstrocytomaAnaplastic AstrocytomaAstrocytoma+19 more
Novartis Pharmaceuticals 151
Early research (Phase 1)Study completedNCT01130077
What this trial is testing

A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas

Who this might be right for
Newly Diagnosed Pediatric Pontine GliomaNewly Diagnosed Pediatric High Grade GliomaRecurrent Pediatric High Grade Glioma+1 more
James Felker 60
Testing effectiveness (Phase 2)Study completedNCT01288235
What this trial is testing

Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation

Who this might be right for
Brain TumorLow Grade GliomaAstrocytoma+2 more
Massachusetts General Hospital 100
Large-scale testing (Phase 3)Not Yet RecruitingNCT07004075
What this trial is testing

FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration

Who this might be right for
Low-grade GliomaPediatric Low-grade GliomaspLGG With BRAF Alteration
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 102
Testing effectiveness (Phase 2)Looking for participantsNCT05180825
What this trial is testing

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy

Who this might be right for
Grade 1 GliomaMixed Glio-neuronal TumorsPleomorphic Xanthoastrocytoma
University Hospital, Strasbourg, France 134
Testing effectiveness (Phase 2)Active Not RecruitingNCT00840047
What this trial is testing

Methionine PET/CT Studies In Patients With Cancer

Who this might be right for
Brain Tumors and/or Solid Tumors IncludingBrain Stem GliomaHigh Grade CNS Tumors+11 more
St. Jude Children's Research Hospital 503
Not applicableTemporarily pausedNCT05934630
What this trial is testing

Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors

Who this might be right for
Anaplastic AstrocytomaDiffuse Brainstem GliomaGlioblastoma Multiforme+15 more
Pediatric Brain Tumor Consortium 300
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