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Results for “Pediatric Low-grade Gliomas”

43 trials

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Showing 20 of 43 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06521567
What this trial is testing

Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Who this might be right for
MelanomaHodgkin LymphomaHigh and Low Grade Glioma+9 more
GlaxoSmithKline 83
Testing effectiveness (Phase 2)Active Not RecruitingNCT01089101
What this trial is testing

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

Who this might be right for
Low Grade GliomaRecurrent Childhood Pilocytic AstrocytomaRecurrent Neurofibromatosis Type 1+3 more
National Cancer Institute (NCI) 217
Early research (Phase 1)Study completedNCT00303940
What this trial is testing

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorKidney Cancer+5 more
National Institutes of Health Clinical Center (CC) 26
Not applicableApproved For MarketingNCT05760586
What this trial is testing

Expanded Access Program (EAP) for Tovorafenib (DAY101) in RAF-Altered, Relapsed or Refractory Low-Grade Glioma

Who this might be right for
Low-grade Glioma
Day One Biopharmaceuticals, Inc.
Testing effectiveness (Phase 2)Looking for participantsNCT06712875
What this trial is testing

MAPK Inhibition Combined With Anti-PD1 Therapy for BRAF-altered Pediatric Gliomas

Who this might be right for
Low Grade GliomaHigh Grade Glioma
Ann & Robert H Lurie Children's Hospital of Chicago 27
Early research (Phase 1)Study completedNCT01682746
What this trial is testing

Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors

Who this might be right for
Brain Tumor, Recurrent
Harry T Whelan, MD 5
Early research (Phase 1)Study completedNCT00100880
What this trial is testing

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

Who this might be right for
Childhood Atypical Teratoid/Rhabdoid TumorChildhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus Tumor+23 more
National Cancer Institute (NCI) 45
Testing effectiveness (Phase 2)Study completedNCT03194906
What this trial is testing

Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors

Who this might be right for
Glioma of BrainCraniopharyngiomaEpendymoma+1 more
St. Jude Children's Research Hospital 41
Testing effectiveness (Phase 2)WithdrawnNCT05222165
What this trial is testing

Study With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 Alterations

Who this might be right for
Advanced Solid TumorCNS TumorRecurrent WHO Grade II Glioma
Helsinn Healthcare SA
Testing effectiveness (Phase 2)Study completedNCT02285439
What this trial is testing

Study of MEK162 for Children With Low-Grade Gliomas

Who this might be right for
Low-Grade GliomasMalignant Neoplasms, BrainSoft Tissue Neoplasms
Children's Hospital Los Angeles 105
Large-scale testing (Phase 3)Active Not RecruitingNCT05566795
What this trial is testing

DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

Who this might be right for
Low-grade GliomaRapidly Accelerated Fibrosarcoma (RAF) Altered GliomaPediatric Low-grade Glioma
Day One Biopharmaceuticals, Inc. 418
Early research (Phase 1)Study completedNCT01130077
What this trial is testing

A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas

Who this might be right for
Newly Diagnosed Pediatric Pontine GliomaNewly Diagnosed Pediatric High Grade GliomaRecurrent Pediatric High Grade Glioma+1 more
James Felker 60
Not applicableLooking for participantsNCT07506239
What this trial is testing

Efficacy of Laser Interstitial Thermal Therapy in Young Persons With Low-grade Glioma

Who this might be right for
Low-grade GliomaRecurrent Low Grade GliomaLow Grade Glioma of Brain+1 more
University of California, San Francisco 40
Early research (Phase 1)Study completedNCT00052780
What this trial is testing

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+22 more
National Cancer Institute (NCI) 72
Testing effectiveness (Phase 2)Study completedNCT03213665
What this trial is testing

Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Hodgkin LymphomaAnn Arbor Stage III Non-Hodgkin Lymphoma+38 more
National Cancer Institute (NCI) 20
Very early researchLooking for participantsNCT05555550
What this trial is testing

Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG

Who this might be right for
GliomaLow-grade GliomaLow Grade Glioma of Brain+2 more
Children's Hospital of Philadelphia 30
Testing effectiveness (Phase 2)Study completedNCT00005952
What this trial is testing

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsChildhood Germ Cell TumorHead and Neck Cancer+5 more
Duke University 30
Not applicableStudy completedNCT01346267
What this trial is testing

Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy

Who this might be right for
Central Nervous System Tumor, PediatricChemotherapy-induced Nausea and VomitingUnspecified Childhood Solid Tumor, Protocol Specific
University of South Florida 187
Testing effectiveness (Phase 2)Looking for participantsNCT05503797
What this trial is testing

Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

Who this might be right for
Cancer Harboring BRAF AlterationsHGGLGG+1 more
Fore Biotherapeutics 254
Testing effectiveness (Phase 2)Study completedNCT04659421
What this trial is testing

Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas

Who this might be right for
Low-grade GliomaPediatric Brain Tumor
Beijing Sanbo Brain Hospital 60
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