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Results for “Pediatric Malignant Brain Tumor -Diffuse Intrinsic Pontine Glioma”

33 trials

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Showing 20 of 33 results

Early research (Phase 1)Ended earlyNCT04341311
What this trial is testing

Phase I Study of Marizomib + Panobinostat for Children With DIPG

Who this might be right for
Diffuse Intrinsic Pontine GliomaPediatric Brainstem GliomaPediatric Brainstem Gliosarcoma, Recurrent+3 more
Dana-Farber Cancer Institute 4
Testing effectiveness (Phase 2)Study completedNCT03257631
What this trial is testing

Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors

Who this might be right for
Central Nervous System NeoplasmsMedulloblastoma
Celgene 53
Early research (Phase 1)Ended earlyNCT03416530
What this trial is testing

ONC201 in Pediatric H3 K27M Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaGlioma, Malignant
Jazz Pharmaceuticals 134
Early research (Phase 1)Ended earlyNCT04239092
What this trial is testing

9-ING-41 in Pediatric Patients With Refractory Malignancies.

Who this might be right for
Refractory CancerRefractory NeoplasmCancer Pediatric+8 more
Actuate Therapeutics Inc. 40
Early research (Phase 1)Active Not RecruitingNCT03478462
What this trial is testing

Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma

Who this might be right for
Pediatric Solid TumorPediatric LymphomaPediatric Brain Tumor+5 more
Cellectar Biosciences, Inc. 30
Not applicableLooking for participantsNCT05839379
What this trial is testing

Targeted Pediatric High-Grade Glioma Therapy

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 350
Testing effectiveness (Phase 2)Ended earlyNCT03330197
What this trial is testing

Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG

Who this might be right for
Pediatric Brain TumorDiffuse Intrinsic Pontine Glioma
Alaunos Therapeutics 6
Testing effectiveness (Phase 2)Looking for participantsNCT05615623
What this trial is testing

Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG

Who this might be right for
Brain Tumor
InSightec 10
Not applicableStudy completedNCT01445288
What this trial is testing

Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaPNETEpendymoma+2 more
National Cancer Institute (NCI) 76
Early research (Phase 1)Study completedNCT02502708
What this trial is testing

Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors

Who this might be right for
Glioblastoma MultiformeGliomaGliosarcoma+5 more
NewLink Genetics Corporation 81
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Early research (Phase 1)Ended earlyNCT03396575
What this trial is testing

Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)

Who this might be right for
Diffuse Intrinsic Pontine Glioma (DIPG)Brain Stem Glioma
University of Florida 11
Early research (Phase 1)Not Yet RecruitingNCT07076498
What this trial is testing

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

Who this might be right for
Glioma
M.D. Anderson Cancer Center 20
Testing effectiveness (Phase 2)Ended earlyNCT04730349
What this trial is testing

Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer

Who this might be right for
EpendymomaEwing SarcomaHigh-grade Glioma+7 more
Bristol-Myers Squibb 15
Not applicableNot Yet RecruitingNCT06093165
What this trial is testing

RE-irradiation of Diffuse MIdline Glioma paTients

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantDiffuse Intrinsic Pontine GliomaDiffuse Glioma+3 more
Rigshospitalet, Denmark 59
Not applicableUnknownNCT04670016
What this trial is testing

HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

Who this might be right for
DIPGBrain Tumor, Pediatric, RecurrentBrain Tumor, DIPG+3 more
University of Calgary 57
Early research (Phase 1)Active Not RecruitingNCT05768880
What this trial is testing

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaDiffuse Midline GliomaRecurrent CNS Tumor, Adult+2 more
Seattle Children's Hospital 72
Not applicableActive Not RecruitingNCT03739372
What this trial is testing

Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

Who this might be right for
GliomaGlioma of BrainCancer+5 more
University of California, San Francisco 44
Early research (Phase 1)Study completedNCT01393912
What this trial is testing

PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma

Who this might be right for
Diffuse Intrinsic Pontine GliomaProgressive or Refractory High-Grade Glioma
St. Jude Children's Research Hospital 55
Testing effectiveness (Phase 2)Ended earlyNCT02758366
What this trial is testing

Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma

Who this might be right for
Glioblastoma (GBM)DIPGBrainstem Glioma, Pediatric+5 more
Meyer Children's Hospital IRCCS 21
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