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Results for “Pediatric Sarcoma, Refractory”

116 trials

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Showing 20 of 116 results

Early research (Phase 1)UnknownNCT02013336
What this trial is testing

Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors

Who this might be right for
Recurrent or Refractory Solid TumorsEwing SarcomaRhabdomyosarcoma+2 more
South Plains Oncology Consortium 30
Early research (Phase 1)WithdrawnNCT01130623
What this trial is testing

A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid Tumors

Who this might be right for
SarcomaNeuroblastomaWilms Tumor+2 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Active Not RecruitingNCT02650401
What this trial is testing

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Who this might be right for
Solid TumorsCNS Tumors
Hoffmann-La Roche 69
Early research (Phase 1)Looking for participantsNCT05857969
What this trial is testing

Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling

Who this might be right for
Recurrent Childhood Acute Myeloid LeukemiaRecurrent Childhood Acute Lymphoblastic LeukemiaRecurrent Childhood Large Cell Lymphoma+15 more
Florida International University 65
Not applicableEnrolling By InvitationNCT07528079
What this trial is testing

Organoid-based Sensitivity-guided Chemotherapy for Advanced / Refractory Pediatric Tumors

Who this might be right for
Soft Tissue Sarcoma, Child
Shanghai Jiao Tong University School of Medicine 30
Early research (Phase 1)Active Not RecruitingNCT03478462
What this trial is testing

Dose Escalation Study of CLR 131 in Pediatric Relapsed/Refractory Malignant Tumors Including Neuroblastoma and Sarcomas

Who this might be right for
Pediatric Solid TumorPediatric LymphomaPediatric Brain Tumor+5 more
Cellectar Biosciences, Inc. 30
Testing effectiveness (Phase 2)Study completedNCT01125800
What this trial is testing

A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB

Who this might be right for
MedulloblastomaRhabdomyosarcomaNeuroblastoma+3 more
Novartis Pharmaceuticals 76
Early research (Phase 1)Study completedNCT01518413
What this trial is testing

Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid Tumors

Who this might be right for
Rhabdomyosarcoma and Other Soft Tissue SarcomasEwing's Sarcoma Family of TumorsOsteosarcoma+2 more
HMeany 17
Testing effectiveness (Phase 2)Study completedNCT04238819
What this trial is testing

Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Who this might be right for
Relapsed Solid TumorRefractory Solid Tumor
Eli Lilly and Company 47
Testing effectiveness (Phase 2)Active Not RecruitingNCT05071209
What this trial is testing

Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors

Who this might be right for
Recurrent Alveolar RhabdomyosarcomaRecurrent Ewing SarcomaRecurrent Lymphoma+5 more
National Cancer Institute (NCI) 31
Early research (Phase 1)Study completedNCT04833582
What this trial is testing

Azenosertib (ZN-c3) in Combination With Gemcitabine in Subjects With Osteosarcoma

Who this might be right for
Osteosarcoma
K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc 31
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Testing effectiveness (Phase 2)Study completedNCT03220035
What this trial is testing

Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Childhood Non-Hodgkin LymphomaAnn Arbor Stage IV Childhood Non-Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 4
Testing effectiveness (Phase 2)Study completedNCT00118326
What this trial is testing

Donor Bone Marrow Transplant in Treating Young Patients With Cancer or a Non-Cancerous Disease

Who this might be right for
Kidney CancerLeukemiaLymphoma+3 more
Fred Hutchinson Cancer Center
Early research (Phase 1)WithdrawnNCT02557854
What this trial is testing

HIFU Hyperthermia With Liposomal Doxorubicin (DOXIL) for Relapsed or Refractory Pediatric and Young Adult Solid Tumors

Who this might be right for
RhabdomyosarcomaNeuroblastomaSarcoma+3 more
Theodore Laetsch
Early research (Phase 1)Looking for participantsNCT07297979
What this trial is testing

Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

Who this might be right for
Ewing Sarcoma
Amgen 50
Early research (Phase 1)Looking for participantsNCT07222735
What this trial is testing

Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas

Who this might be right for
SarcomaChildhood OsteosarcomaChildhood Rhabdomyosarcoma+2 more
St. Jude Children's Research Hospital 42
Early research (Phase 1)Active Not RecruitingNCT04483778
What this trial is testing

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

Who this might be right for
Pediatric Solid TumorGerm Cell TumorRetinoblastoma+14 more
Seattle Children's Hospital 68
Testing effectiveness (Phase 2)Study completedNCT00055939
What this trial is testing

Exatecan Mesylate in Treating Children With Relapsed or Refractory Rhabdomyosarcoma

Who this might be right for
Sarcoma
Daiichi Sankyo
Early research (Phase 1)Study completedNCT01132911
What this trial is testing

A Phase I Study of Vorinostat and Bortezomib in Children With Refractory of Recurrent Solid Tumors, Including CNS Tumors and Lymphomas

Who this might be right for
LymphomaSarcomaWilmsTumor+1 more
National Cancer Institute (NCI) 5
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